CAS: 132685-02-0; (2S,2'S)-3,3'-(1,1'-(Ethane-1,1-Diyl)Bis(1H-Indole-3,1-Diyl))Bis(2-Aminopropanoic Acid)
该化合物是氨基酸锥体合成化合物,以其在蛋白合成中的作用和作为血清素的前体而著称.该化合物具有独特的结构,其中两个L-tryptophan单元通过乙基环桥连接,加强了其稳定性,并有可能改变其生物活动,而与自由试金素相比.其特点是芳香异的无花边链,有助于其参与各种生物化学互动.该化合物可能表现出诸如极溶剂溶性等特性,其在生物系统中的行为可能受到乙基苯乙烯联系的影响.作为试金的衍生物,它也可能对...
- 英文名称(2S,2'S)-3,3'-(1,1'-(Ethane-1,1-Diyl)Bis(1H-Indole-3,1-Diyl))Bis(2-Aminopropanoic Acid)
- 中文名称粉色E
- IUPAC名称(2S,2'S)-3,3'-(1,1'-(Ethane-1,1-diyl)bis(1H-indole-3,1-diyl))bis(2-aminopropanoic acid)
- 其它别名1,1'-Ethylidene-Bis(L-Tryptophan); 1,1'-Ethylidene-Bis(L-Trytophan); Peak E; Ebt; Contaminant 97; Tryptophan Related Compound A (15 Mg) (1,1'-Ethylidene-Bis-(L-Tryptophan)); Tryptophan Related Compound A; Tadalafil Impurity Q
- CAS编号132685-02-0
- MFCD编号:MFCD09842569
- FDA UNII编号:XP857D0YL2
- 分子式:C24H26N4O4分子量:434.5
- 产品CID: 493148
- 产品分类分析化学 → 标准品 → 药典标准品和杂质标准品
物理性质
MSDS等安全信息
- GHS符号GHS07
- 警示词Warning
- 危险描述H302-H315-H319-H335
- 防范说明P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501
- UN编号NONH for all modes of transport
- 安全声明H303+H313+H333
- 危险类别码This chemical is the suspected cause of Eosinophilia-Myalgia syndrome, a toxic epidemic that occurred in 1989 among those who ingested contaminated L-tryptophan as a dietary supplement. Another scleroderma-like disorder caused by environmental poisoning occurred in Spain in 1981: toxic oil syndrome after ingestion of rapeseed oil contaminated with aromatic amines. [Rosenstock, p. 538]
- WGK Germany3
上下游产品
acetaldehyde L-TryptophanL-Tryptophan (1S,3S)-1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (-)-(1S,3S)-1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid合成工艺路线路线简述
📜乙醛,L-色氨酸置于盐酸体系中,用 水 用作溶剂,化学反应 0.33H,以30%的收率获得粉色e
参考文献:1,1'-Ethylidenebis(L-Tryptophan),Structure Determination Of Contaminant "97"-Implicated In The Eosinophilia-Myalgia Syndrome (Ems)
标题:1,1'-Ethylidenebis(L-Tryptophan),Structure Determination Of Contaminant "97"-Implicated In The Eosinophilia-Myalgia Syndrome (Ems)
摘要:The Condensation Of Tryptophan And Acetaldehyde Affords A Bisindolylaminal Of Tryptophan Which Is Indistinguishable From Contaminant "97". The Formation And Decomposition Of Aminals Is Addressed In Light Of Epidemiological Evidence Linking Them To A Recent Outbreak Of Ems.
Doi:10.1016/s0040-4039(00)74469-8
海关参考信息
- 2902200000-苯
2905121000-正丙醇
2912110000-甲醛
2912120000-乙醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:Rosenstock - Rosenstock L, Cullen MR, Brodkin CA, Redlich CA (eds). Textbook of Clinical Occupational and Environmental Medicine, 2nd Ed. Philadelphia: Elsevier Saunders, 2004., p. 538
摘要:Suzuki S, Tourkina E, Ludwicka A, Hampton M, Bolster M, Maize J, Silver R. A contaminant of L-tryptophan enhances expression of dermal collagen in a murine model of eosinophilia myalgia syndrome. Proc Assoc Am Physicians. 1996 Jul;108(4):315–22.
参考文献:10.1007/bf00195987
摘要:Driskell WJ, Ashley DL, Grainger J, Sirimanne SR, Mazzola EP, Page SW, Needham LL, Hill RH. Identification of decomposition products of 1,1′-ethylidenebis [L-tryptophan], a compound associated with eosinophilia-myalgia syndrome. Bulletin of Environmental Contamination and Toxicology. 1992 May;48(5):679–87. doi: 10.1007/bf00195987.
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