CAS: 132-32-1; 9-Ethyl-9H-Carbazol-3-Amine

该化合物是卡巴诺家族的有机化合物,其特点是其引信环状结构,包括氮原子;该化合物具有氨基组(-NH2)和与卡巴诺框架相连的乙基组(-C2H5),有助于其独特的化学特性;该化合物一般是室内温度固态,呈现出各种颜色,取决于其纯度和形态;3-Amino-9-乙基碳酸酯因其在有机电子系统中的应用而闻名,特别是在开发有机发光二极管(OLEDs)和在各种工业过程中的染色体;氨基组的存在增强了其再活动性,使其得以参与各种化学反应,包括组合反应和聚合;此外,已对其潜在的生物活动进行了研究,包括抗胃素特性;安全数据表明,应当谨慎处理,因为接触该物质可能对健康造成危害.

结构式图片

相似化合物

61166-04-9 86-28-2 86-20-4

欧盟法规

统一分类与标签ECHA物质ECHA物质工作场所安全标识要求食品接触材料-禁用CMR物质C&L通报化妆品禁用物质清单REACH预注册废弃物危险特性清单

上下游产品

CAS号86-20-4 9-乙基-3-硝基咔唑 | CAS号57102-97-3 3-溴-9-乙基咔唑 | CAS号104563-32-8 3-azoxy-9-ethyl... | CAS号82298-50-8 9,9'-diethyl-Z-... | CAS号86-28-2 N-乙基咔唑 | CAS号144539-45-7 1-(叔丁氧基羰基)-4-亚甲... | CAS号18908-07-1 3-甲氧基苯基异氰酸酯 | CAS号86-74-8 咔唑 | CAS号3077-85-8 3-硝基-9h-咔唑 | CAS号80546-37-8 2,5-dichloro-3,... | CAS号80776-28-9 9-ethyl-4-nitro... | CAS号80776-31-4 N-(9-ethyl-4,6-... | CAS号80776-35-8 Carbamicacid, (... | CAS号90520-55-1 N-(9-ethylcarba... | CAS号50668-21-8 3-碘-9-乙基咔唑 | CAS号507245-65-0 1-(9-ethylcarba... | CAS号6358-26-5 Phenol,4-[(9-et...

合成工艺路线路线简述

    3-硝基-N-乙基咔唑置于盐酸,Tin(Ll) Chloride体系中,用 乙醇 用作溶剂,化学反应生成3-氨基-9-乙基咔唑
    参考文献:基于咔唑的开启式荧光探针,用于检测水溶液中的肼
    标题:基于咔唑的开启式荧光探针,用于检测水溶液中的肼
    摘要:摘要基于咔唑的荧光探针2-(9-乙基-9H-咔唑-3-基)异吲哚啉-1,3-二酮的检测限低(2.673x10-6 M),是用于检测肼的gabriel反应设计和合成.与其他氨基化合物相比,该探针对肼具有选择性响应,并具有明显的荧光增强作用.此外,试纸实验表明了其在水溶液中肼的环境监测中的巨大潜力.
    Doi:10.1016/j.Ica.2018.03.033

    海关参考信息

    专利信息


    专利号:US-6376475-B1
    优先权日:1997-05-30
    标 题 :Control of immune responses by modulating activity of glycosyltransferases
    发明人:MARTH JAMEY D; PAULSON JAMES C
    权利人:ABARON BIOSCIENCES INC; UNIV CALIFORNIA
    摘要:The invention provides methods for inhibiting immune responses by inhibiting the biosynthesis of the sialyl galactosides that are involved in immune responses. In particular, B lymphocyte-mediated immune responses are mediated by interfering with synthesis of α2,6 sialylgalactosides, while T lymphocyte-mediated immune responses are inhibited by blocking synthesis of α2,3 sialylgalactosides. The inhibition is accomplished by, for example, inhibiting the activity of a glycosyltransferase involved in synthesis of the respective sialyl galactoside.

    专利号:US-9567307-B2
    优先权日:2011-01-07
    标题:Amination of aryl alcohol derivatives
    发明人:GARG NEIL K; RAMGREN STEPHEN D; SILBERSTEIN AMANDA L; QUASDORF KYLE W
    权利人:GARG NEIL K; RAMGREN STEPHEN D; SILBERSTEIN AMANDA L; QUASDORF KYLE W; UNIV CALIFORNIA
    摘要:Embodiments of the invention provide methods and materials for chemical cross-coupling reactions that utilize aryl alcohol derivatives as cross-coupling partners. Embodiments of the invention include methods for the amination of aryl sulfamates and carbamates, which are attractive cross-coupling partners, particularly for use in multistep synthesis. Illustrative embodiments include versatile means to use simple derivatives of phenol as precursors to polysubstituted aryl amines, as exemplified by a concise synthesis of the antibacterial drug linezolid.

    专利号:US-5232829-A
    优先权日:1989-09-29
    标 题 :Detection of chlamydia trachomatis by polymerase chain reaction using biotin labelled lina primers and capture probes
    发明人:LONGIARU MATHEW; SILVER SHERYL B; SULZINSKI MICHAEL A
    权利人:HOFFMANN LA ROCHE
    摘要:The present invention relates to the synthesis of amplified biotin-labelled DNA target sequences of Chlamydia trachomatis by polymerase chain reaction techniques and the detection of such sequences by a microtiter plate having plurality of wells and having bound thereto oligonucleotide capture probe complementary to said target sequence.

    专利号:EP-0942745-B1
    优先权日:1996-08-26
    标题:Use of hyaluronidase
    发明人:TUFVESON GUNNAR; HAELLGREN ROGER; JOHNSSON CECILIA; WAHLBERG JAN
    权利人:TUFVESON GUNNAR; HAELLGREN ROGER; JOHNSSON CECILIA; WAHLBERG JAN
    摘要:The use of hyaluronidase in the manufacturing of a drug for the treatment of conditions of interstitial edema in connection with organ grafting associated with an increased local content of hyaluronan in the connective tissue of a mammal. The drug comprises hyaluronidase in an amount giving a daily dosage of from 1 to 100,000 IU/kg body weight when given locally or systemically to a mammal. A method of treating conditions of interstitial edema in connection with organ grafting associated with an increased local synthesis of hyaluronan by systemic or local treatment with a pharmaceutical comprising hyaluronidase.

    专利号:US-6251663-B1
    优先权日:1996-04-24
    标题 :Recombinant eukaryotic plasmids containing allergen-gene and use thereof for the prevention and/or treatment of allergic diseases
    发明人:HSU CHING-HSIANG; CHUA KAW-YAN; TAO MI-HUA; HSIEH KUE-HSIUNG
    权利人:JEN WEN CO LTD
    摘要:The present invention relates to recombinant eukaryotic plasmids comprising an eukaryotic expression vector and an allergen gene for the prevention and/or treatment of allergic diseases. When the recombinant vector containing allergen-gene administrate to an individual in need of such prevention and/or treatment by intramuscular injection, intranasal delivery or intratracheal delivery, the production of allergen-specific IgE synthesis can be inhibited. The invention also relates to the pharmaceutical compositions comprising the the recombinant vector for use in the the prevention and/or treatment of allergic diseases and the production of allergen-specific IgE synthesis. A method for the prevention and/or treatment of allergic diseases is also provided.

    专利号:US-5780675-A
    优先权日:1995-04-28
    标 题:Deoxygossylic compounds
    发明人:ROYER ROBERT D; DECK LORRAINE M; VANDERJAGT DAVID L
    权利人:UNIV NEW MEXICO
    摘要:The invention provides deoxygossylic compounds having useful biological activities, and methods for the synthesis of these and related compounds. The invention further provides valuable intermediates for the synthesis of the compounds, and pharmaceutical compositions containing biologically active compounds according to the invention.
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    主要参考文献

    [参考文献]: A Bertolo, Et Al. Injectable Microcarriers As Human Mesenchymal Stem Cell Support And Their Application For Cartilage And Degenerated Intervertebral Disc Repair. Eur Cell Mater. 2015 Jan 12:29:70-80; Discujssion 80-1.
    [参考文献]: L M M Costes, Et Al. Endogenous Vagal Activation Dampens Intestinal Inflammation Independently Of Splenic Innervation In Postoperative Ileus. Auton Neurosci. 2014 Oct:185:76-82.
    [参考文献]: Lisa G M Van Baarsen, Et Al. Heterogeneous Expression Pattern Of Interleukin 17A (Il-17A), Il-17F And Their Receptors In Synovium Of Rheumatoid Arthritis, Psoriatic Arthritis And Osteoarthritis: Possible Explanation For Nonresponse To Anti-Il-17 Therapy. Arthritis Res Ther. 2014 Aug 22;16(4):426.
    [参考文献]: M Trondsen, Et Al. Induction Of Local Secretory Iga And Multifunctional Cd4 T-Helper Cells Following Intranasal Immunization With A H5N1 Whole Inactivated Influenza Virus Vaccine In Balb/c Mice. Scand J Immunol. 2015 May;81(5):305-17.
    [参考文献]: Phuong N Dang, Et Al. Driving Cartilage Formation In High-Density Human Adipose-Derived Stem Cell Aggregate And Sheet Constructs Without Exogenous Growth Factor Delivery. Tissue Eng Part A. 2014 Dec;20(23-24):3163-75.

    合成参考文献


    参考文献:10.1186/1743-422x-7-38
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    参考文献:10.1371/journal.pbio.1001099
    摘要:Wu G, Liu N, Rittelmeyer I, Sharma AD, Sgodda M, Zaehres H, Bleidißel M, Greber B, Gentile L, Han DW, Rudolph C, Steinemann D, Schambach A, Ott M, Schöler HR, Cantz T. Generation of Healthy Mice from Gene-Corrected Disease-Specific Induced Pluripotent Stem Cells. PLoS Biol. 2011 Jul 12;9(7):e1001099. doi: 10.1371/journal.pbio.1001099.
    参考文献:10.1007/s00428-005-0105-1
    摘要:Heiskala K, Giles-Komar J, Heiskala M, Andersson LC. High expression of RELP (Reg IV) in neoplastic goblet cells of appendiceal mucinous cystadenoma and pseudomyxoma peritonei. Virchows Arch. 2006 Mar;448(3):295–300. doi: 10.1007/s00428-005-0105-1.
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