CAS: 76005-99-7; 2-Methoxy-4-Methylpyridin-3-Amine

相似化合物

160590-36-3 1823051-72-4 6635-91-2

上下游产品

2-methoxy-4-methyl-3-nitropyridine methanol 3-Amino-2-chloro-4-methylpyridine pyridine7-chloro-1H-pyrazolo3,4-cpyridine pyridin-7(6H)-one1H-pyrazolo3,4-cpyridin-7(6H)-one pyridine7-methoxy-1H-pyrazolo3,4-cpyridine pyridine7-anilino-1H-pyrazolo3,4-cpyridine

📜2-甲氧基-3-硝基-4-甲基吡啶置于palladium On Activated Charcoal,氢气体系中,用 乙醇 作为反应溶剂,化学反应生成 2-甲氧基-3-氨基-4-甲基吡啶
参考文献:一些新型无环c-核苷的合成和抗病毒活性评估.
标题:一些新型无环c-核苷的合成和抗病毒活性评估.
摘要:描述了新颖的5-氨基或7-羟基取代的吡唑并[4,3-B]吡啶和吡唑并[3,4-C]吡啶无环c-核苷的制备.它们的合成是通过适当取代的锂甲基吡啶与2-苄氧基乙氧基甲基氯化物的缩合,然后进行吡唑环环化来进行的.评估了这些化合物对多种病毒的抗病毒活性,但发现它们在亚毒性浓度下无活性.
DOI:10.1248/cpb.56.775

专利信息

专利号:US-5656634-A
优先权日:1991-03-21
标题 :N-aryl and N-heteroarylamide and urea derivatives as inhibitors of acyl coenzyme A: cholesterol acyl transferase (ACAT)
发明人：CHANG GEORGE; HAMANAKA ERNEST S; MCCARTHY PETER A; TRUONG THIEN V; WALKER FREDERICK J
权利人:PFIZER
摘要:Compounds of the formula ##STR1## the pharmaceutically acceptable salts thereof, wherein Q and R 1 are as defined below, and novel carboxylic acid and acid halide intermediates used in the synthesis of such compounds. The compounds of formula I are inhibitors of acyl coenzyme A: cholesterol acyltransferase (ACAT) and are useful as hypolipidemic and antiatherosclerosis agents.

专利号:US-8129411-B2
优先权日:2005-12-30
标题:Organic compounds
发明人：EHARA TAKERU; GROSCHE PHILIPP; IRIE OSAMU; IWAKI YUKI; KANAZAWA TAKANORI; KAWAKAMI SHIMPEI; KONISHI KAZUHIDE; MOGI MUNETO; SUZUKI MASAKI; YOKOKAWA FUMIAKI
权利人:EHARA TAKERU; GROSCHE PHILIPP; IRIE OSAMU; IWAKI YUKI; KANAZAWA TAKANORI; KAWAKAMI SHIMPEI; KONISHI KAZUHIDE; MOGI MUNETO; SUZUKI MASAKI; YOKOKAWA FUMIAKI; NOVARTIS AG
摘要:The invention relates to 3,5-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,5-substituted piperidine compound, and/or a method of treatment comprising administering a 3,5-substituted piperidine compound, a method for the manufacture of a 3,5-substituted piperidine compound, and novel intermediates and partial steps for its synthesis. n The compounds have the formula I′ n nwherein R1, R2, T, R3 and R4 are as defined in the specification.