CAS: 57620-49-2; 4-Methyl-4-Nitrovaleraldehyde

上下游产品

4-Methyl-4-Nitrovaleronitrile 16507-00-9
4-Methyl-4-Nitropentanol 5215-92-9
4-甲基-4-硝基戊酸甲酯 Methyl 4-Methyl-4-Nitropentanoate 16507-02-1

📜5,5-二甲基-1-吡咯啉-N-氧化物置于oxygen体系中,用 水 作为反应溶剂,化学反应生成 4-甲基-4-硝基戊醛
参考文献:Pt 纳米晶体/卟啉 Mof 上的单线态氧参与选择性光氧化:光热效应和 Pt 电子态的作用
标题:Pt 纳米晶体/卟啉 Mof 上的单线态氧参与选择性光氧化:光热效应和 Pt 电子态的作用
摘要:在温和条件下使用分子氧在芳族醇氧化中对醛的选择性控制仍然是一个巨大的挑战.在这项工作中,我们通过整合 Pt 纳米晶体和卟啉金属有机骨架 (Mof) Pcn-224(M) 设计并合成了 Pt/pcn-224(M) 复合材料.基于协同光热效应和单线态氧的产生,该复合材料在环境温度下通过 1 Atm O2 光氧化芳香醇表现出优异的催化性能.此外,与肖特基结的功能相反,热电子从等离子体 Pt 注入 Pcn-224(M) 会降低 Pt 表面的电子密度,因此,通过改变光强度,可以通过肖特基结和等离子体效应之间的竞争来优化催化性能.据我们所知,这不仅是关于单线态氧参与将芳香醇选择性氧化为醛的前所未有的报告,也是关于 Mof 光热效应的首次报告.
DOI:10.1021/jacs.6B12074

专利信息

专利号:US-2005014954-A1
优先权日:2001-11-22
标 题:Pyrrole synthesis
发明人：OHRLEIN REINHOLD; BAISCH GABRIELE
摘要:The invention relates to a novel process for the preparation of N-substituted pyrroles, especially of formula (V), wherein the radicals are as defined in the description, by intermolecular aza-Wittig reaction starting from organic azides and 1,4-dioxo compounds. The invention relates also to novel iminophosphorane intermediates for this synthesis. The resulting pyrroles are useful, for example, in the organic synthesis of pharmaceuticals or other active substances and chemicals.

专利号:US-8026383-B2
优先权日:2001-07-06
标题:Process for the preparation of intermediates useful in the synthesis of statin derivatives
发明人：OEHRLEIN REINHOLD; BAISCH GABRIELE; END NICOLE; BURKHARDT STEPHAN; STUDER MARTIN
权利人:BASF SE
摘要:The invention relates to novel synthesis methods for the preparation of statin derivatives, which methods proceed by way of a key intermediate of formula I n nwherein X is halogen, acyloxy, activated hydrocarbyloxy, activated hydrocarbylthio or —N(CH 3 )OCH 3 , R a is a hydroxy-protecting group and R b is a carboxy-protecting group, and, as well as to the compound of formula I, to further new intermediates and methods for their preparation by Friedel-Crafts acylation.

专利号:US-7692034-B2
优先权日:2001-07-06
标题:Process for the preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives via 6-cyano syn 3,5-dihydroxy hexanoic acid derivatives
发明人：OEHRLEIN REINHOLD; BAISCH GABRIELE; KIRNER HANS JUERG; BIENEWALD FRANK; BURKHARDT STEPHAN; STUDER MARTIN
权利人:TEVA PHARMA
摘要:The invention relates to novel synthesis methods for the preparation of the intermediates, which are suitable for the preparation of statin derivatives, especially to novel synthesis methods of the intermediate of formula VI wherein R a and R c are each independently of the other hydrogen or a hydroxy-protecting group or together are a bridging hydroxy-protecting group, and R b is a carboxy-protecting group, which methods are carried out by conversion of the intermediate of formula XIX wherein R a and R c are each independently of the other hydrogen or a hydroxy-protecting group, and R b is a carboxy-protective group.

专利号:US-7504532-B2
优先权日:2001-07-06
标 题 :Process for the preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives, intermediates thereof and methods for their preparation
发明人：OEHRLEIN REINHOLD; BAISCH GABRIELE; KIRNER HANS JOERG; BURKHARDT STEPHAN; STUDER MARTIN; BIENEWALD FRANK
权利人:TEVA PHARMA
摘要:Synthesis methods for the preparation of intermediates which are suitable for the preparation of statin derivatives, and especially to synthesis methods for the intermediate of formula (VI) wherein R a ′ and R c ′ are each independently of the other hydrogen or hydroxy-protecting group, or together are a bridging hydroxy-protecting group; and R b is a carboxy-protecting group.

专利号:US-7420078-B2
优先权日:2001-07-06
标 题 :Process for the preparation of intermediates useful in the synthesis of statin derivatives especially 7-amino 3,5-dihydroxy heptanoic acid derivatives, and intermediates thereof

专利号:EP-1404639-A1
优先权日:2001-07-06
标题:Process for the preparation of intermediates useful in the synthesis of statin derivatives especially 7-amino 3,5-dihydroxy heptanoic acid derivatives, and intermediates thereof