CAS: 3314-30-5; 1H-Benzo[d]Imidazole-2-Carbaldehyde

相似化合物

2849-93-6 4856-97-7 5805-53-8

上下游产品

CAS号4856-97-7 2-羟甲基苯并咪唑 | CAS号615-15-6 2-甲基苯并咪唑 | CAS号95-54-5 邻苯二胺(OPD) | CAS号13109-82-5 2-(Diethoxymeth... | CAS号5466-57-9 2-(二氯甲基)苯并咪唑 | CAS号144-62-7 草酸 | CAS号2849-93-6 1H-苯并咪唑-2-羧酸 | CAS号101278-94-8 1,2-bis(1H-benz... | CAS号6965-02-2 (2-苯并咪唑-2-基)-氢苯并咪唑 | CAS号77200-84-1 1-(benzoimidazo... | CAS号50-97-5 1H-Benzimidazol...

📜2-(二氯甲基)苯并咪唑置于硫酸体系中,用 水 作为反应溶剂,化学反应 1.0H,以85.3%的收率获得产物苯并咪唑-2-甲醛
参考文献:具有酪氨酸激酶抑制活性的2-吲哚酮衍生物 及其制备方法与应用
标题:具有酪氨酸激酶抑制活性的2-吲哚酮衍生物 及其制备方法与应用
摘要:本发明公开了一类具有酪氨酸激酶抑制活性的2‑吲哚酮衍生物,其几何异构体,其药用盐以及这些化合物的制备方法及其应用.通过酪氨酸激酶抑制活性评价,确证具有非常好的酪氨酸激酶抑制活性的化合物,因而具有潜在的抗肿瘤活性,可作为活性成分制备预防和治疗肿瘤疾病的药物(抗肿瘤药物),本发明将为肿瘤治疗提供了研究和实施基础,应用前景广阔.

专利信息

专利号:US-5663368-A
优先权日:1993-07-14
标 题:Synthesis of acid addition salts of hydroxylamines
发明人：FLISAK JOSEPH R; ROSS STEPHEN TOREY
权利人:SMITHKLINE BEECHAM CORP
摘要:This invention relates to novel diastereomeric acid addition salts of homochiral hydroxylamines, to processes for obtaining such, to processes for the conversion thereof to the corresponding homochiral hydroxylamines, to certain novel homochiral hydroxylamines and the processes for using these as intermediates.

专利号:US-9845282-B1
优先权日:2016-08-12
标题 :Palladium catalyzed synthesis of ester compounds
发明人：EL ALI BASSAM M; IBRAHIM MANSUR B; SULEIMAN RAMI K
权利人:UNIV KING FAHD PET & MINERALS
摘要:A catalytic process for synthesizing an ester compound, and a catalytic process for synthesizing an amide compound, wherein a solid-supported palladium catalyst is used to catalyze an alkoxycarbonylation reaction of an aryl halide to form the ester compound, or to catalyze an aminocarbonylation reaction of an aryl halide to form the amide compound. Various embodiments of each of the processes are also provided.

专利号:US-7754913-B2
优先权日:2006-07-11
标题:Synthesis of isotopically labeled alpha-keto acids and esters
发明人：MARTINEZ RODOLFO ANTONIO; MINTON MARK; ANDERSON III FRANK ELBERT; ORTIZ ERICK GABRIEL; TORTOLANI KENNETH EDMUND
权利人:CAMBRIDGE ISOTOPE LAB INC
摘要:Isotopically labeled alpha-keto acids and esters are disclosed herein. Also disclosed are methods of synthesizing isotopically labeled alpha-keto acids and esters.

专利号:US-7612106-B2
优先权日:2004-12-23
标题 :Fused pyrazole derivatives and methods of treatment of metabolic-related disorders thereof
发明人：BOATMAN P DOUGLAS; SCHRADER THOMAS O; SEMPLE GRAEME; SKINNER PHILIP J; JUNG JAE-KYU
权利人:ARENA PHARM INC
摘要:The present invention relates to certain fused pyrazole derivatives of Formula (Ia), and pharmaceutically acceptable salts thereof, which exhibit useful pharmacological properties, for example, as agonists for the RUP25 receptor. n nAlso provided by the present invention are pharmaceutical compositions containing compounds of the invention, and methods of using the compounds and compositions of the invention in the treatment of metabolic-related disorders, including dyslipidemia, atherosclerosis, coronary heart disease, insulin resistance, type 2 diabetes, Syndrome-X and the like. In addition, the present invention also provides for the use of the compounds of the invention in combination with other active agents such as those belonging to the class of α-glucosidase inhibitors, aldose reductase inhibitors, biguanides, HMG-CoA reductase inhibitors, squalene synthesis inhibitors, fibrates, LDL catabolism enhancers, angiotensin converting enzyme (ACE) inhibitors, insulin secretion enhancers, DP receptor antagonists, and the like.

专利号:EP-1836163-B1
优先权日:2004-12-23
标题 :Pyrrolidine derivatives for the treatment of a disease depending on the activity of renin
发明人：BREITENSTEIN WERNER; COTTENS SYLVAIN; EHRHARDT CLAUS; JACOBY EDGAR; LORTHIOIS EDWIGE LILIANE JEANNE; MAIBAUM JUERGEN KLAUS; OSTERMANN NILS; SELLNER HOLGER; SIMIC OLIVER
权利人:NOVARTIS AG
摘要:Novel 3-mono-, 3,4-di- and 3,4,4,-tri-substituted pyrrolidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on inappropriate activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on inappropriate activity of renin; the use of a compound of that class in the treatment of a disease that depends on inappropriate activity of renin; pharmaceutical formulations comprising a said substituted pyrrolidine compound, and/or a method of treatment comprising administering a said substituted pyrrolidine compound, a method for the manufacture of said substituted pyrrolidine compounds, and novel intermediates and partial steps for their synthesis are described. The substituted pyrrolidine compounds are especially of the formula I wherein the substituents are as described in the specification.

专利号:US-2008161593-A1
优先权日:2006-07-11
标题 :Synthesis of isotopically labeled alpha-keto acids and esters