CAS: 3187-58-4; Methyl 2,4-Dihydroxy-6-Methylbenzoate

该化合物是属于酯类的有机化合物,产自丙烯酸,具有甲基酯功能组的特点,一般看起来无色可粉黄,有香味.已知甲基或硅酸因其芳香特性而在香水和香味领域的潜在应用.此外,它展示了生物活动,包括抗微生物和抗硫特性,使其对制药和化妆品配方感兴趣.该化合物溶于有机溶剂,可提高其在各种化学工艺中的效用.在正常条件下,该化合物的稳定性便于处理和储存.然而,与许多有机化合物一样,它应当谨慎处理,遵循适当的安全准则,以减轻任何潜在的健康风险.

结构式图片

上下游产品

diazomethane diethyl ether orsellinic acid methanol2-hydroxy-4-methoxy-6-methyl-benzoic acid methyl ester methyl haematommate methyl isohaematommate methyl 2,4-dihydroxy-3,5-dibromo-6-methylbenzoate

合成工艺路线路线简述

    📜乙酰乙酸甲酯置于盐酸,正丁基锂,Sodium Hydride体系中,化学反应生成2,4-二羟基-6-甲基苯甲酸甲酯
    参考文献:丙酮酸及其衍生物的合成途径
    标题:丙酮酸及其衍生物的合成途径
    摘要:探索了到环戊酸衍生物的合成途径,并描述了这些分子全部合成的收敛途径.
    Doi:10.1016/s0040-4020(01)85090-0

    海关参考信息

    专利信息


    专利号:US-2021253509-A1
    优先权日:2018-06-28
    标 题 :Synthesis of (+)-cannabinoids and their therapeutic effects

    专利号:EP-1300403-A1
    优先权日:2001-10-02
    标 题 :Process for the manufacture of hypoxyxylerone derivatives
    发明人:GIMBERT YVES; CHEVENIER EMMANUEL; GREEN ANDREW E; MASSARDIER CHRISTINE; PIETTRE ARNAUD
    权利人:AVENTIS PHARMA SA
    摘要:The present invention relates to the total synthesis ofnhypoxyxylerone derivatives (formula I) and their biologicalnactivities. n R1-R5 are as described in the description.

    专利号:US-9359298-B2
    优先权日:2011-12-23
    标题:Cajanine structure analogous compound, preparation method and use
    发明人:LI ZHUORONG; JI XINGYUE; Xue situ; ZHENG GUANGHUI; LI YUHUAN; TAO PEIZHEN; JIANG JIANDONG
    权利人:INST MED BIOTECHNOLOGY CAMS
    摘要:Provided are cajanine structure analogous compounds, synthesis method and pharmacological effects thereof, the compounds of the present invention having the structure as represented by general formulas I, II, III, IV and V. Also provided are pharmaceutical compositions containing the compounds as active ingredient, and uses thereof; the compounds of the present invention having the pharmacological activities such as anti-virus, anti-virus-infection, nerve protection, anti-metabolic-diseases and the like. Also provided is a chemical total synthesis preparation method of the natural products cajanine, cajanine A and cajanine C. The present invention lays a foundation for the in-depth study and development of the compounds as clinical drugs in the future.

    专利号:CN-101817745-A
    优先权日:2009-12-29
    标 题:A kind of chemical synthesis method of 3,5-dichloro-4-hydroxyl-2-methoxy-6-methyl-benzoic acid

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Enantioselective Synthesis Of The 3C-Protease Inhibitor (-)-Thysanone By A Staunton-Weinreb Annulation Strategy
    作者:Margaret Brimble,Jonathan Sperry,Tsz Yuen |发布日期:2009.8
    摘要:The Total Synthesis Of (-)-Thysanone Is Described. The Key Step Involves The Addition Of An O-Toluate Anion To A Lactone To Create The Naphthopyran Framework (Staunton-Weinreb Annulation). This Synthesis Further Confirms The Absolute Stereochemistry Of The Natural Product To Be 1R,3S. Thysanone - Staunton-Weinreb Annulation - Total Synthesis - Natural Products - Polycycles

    合成参考文献


    参考文献:10.1038/ncb3255
    摘要:Lin R, Elf S, Shan C, Kang HB, Ji Q, Zhou L, Hitosugi T, Zhang L, Zhang S, Seo JH, Xie J, Tucker M, Gu TL, Sudderth J, Jiang L, Mitsche M, DeBerardinis RJ, Wu S, Li Y, Mao H, Chen PR, Wang D, Chen GZ, Hurwitz SJ, Lonial S, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Lei Q, Brat DJ, Ye K, Boggon TJ, He C, Kang S, Fan J, Chen J. 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. Nat Cell Biol. 2015 Nov;17(11):1484–96.
    摘要:Marsini, M. A.; Pettus, T. R. R., Science of Synthesis, (2007) 31, 457.
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