CAS: 298716-03-7; (1R,4R)-4-((Tert-Butoxycarbonyl)Amino)Cyclopent-2-Enecarboxylic Acid
该化合物是有机化合物,具有独特的双环结构,具有环球环状环状,有助于其反应和在有机合成中的潜在应用.一个叔丁氧碳基(Boc)组的存在表明,它有可能被用作合成化学中氨胺的一种保护组,促进其他反应场所的选择性功能化.箱状酸功能组提供了酸性,允许各种化学环境中的潜在相互作用.该组的立体化学学以(1R,4R)配置为标志,它提出了能够影响其生物活动和回性的具体空间安排.总体而言,该物质可能因其结构特征和功能组而有兴趣进行制药和新化合物的开发,这些特性和功能群可以被操纵用于各种合成途径.
- 英文名称(1R,4R)-4-((Tert-Butoxycarbonyl)Amino)Cyclopent-2-Enecarboxylic Acid
- 中文名称(1R,4R)-4-((叔丁氧基羰基)氨基)环戊-2-烯-1-羧酸
- IUPAC名称(1R,4R)-4-((tert-butoxycarbonyl)amino)cyclopent-2-ene-1-carboxylic acid
- 其它别名(1R,4R)-4-(Boc-氨基)-2-环戊烯羧酸; (1R,4R)-4-(Tert-Butoxycarbonylamino)Cyclopent-2-Enecarboxylic Acid
- CAS编号298716-03-7
- MFCD编号:MFCD12405610
- EINECS号:871-730-2
- 分子式:C11H17NO4分子量:227.26
- 产品CID: 1280838
- 产品分类有机原料→分子砌块→脂肪环类化合物→环戊烷类化合物
相似化合物
108999-93-5 151907-79-8 151907-80-1物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
CAS号168683-02-1 (1S,4R)-4-[[叔丁氧... | CAS号79200-56-9 (-)-文斯内酯 | CAS号151792-53-9 (1R,4S)-叔-丁基3-氧...合成工艺路线路线简述
- 合成目标产物 (1R,4R)-4-(Tert-Butoxycarbonylamino)Cyclopent-2-Enecarboxylic Acid 主要起始原料 4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-2-Cyclopentene-1-Carboxylic Acid Methyl Ester
- (文献来源)合成步骤主要原料 4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-2-Cyclopentene-1-Carboxylic Acid Methyl Ester
📜(1S,4R)-4-甲基环戊-2-烯甲酸甲酯盐酸盐置于sodium Methylate,三乙胺体系中,用 甲醇,二氯甲烷 用作溶剂,化学反应 42.33H,反应生成(1R,4R)-4-(Boc-氨基)-2-环戊烯羧酸
参考文献: Production Of Trans-4-Aminocyclopent-2-Ene-1-Carboxylic Acid Derivatives[fr] Production De Dérivés D'Acide Trans-4-Aminocyclopent-2-ène-1-Carboxylique
标题: Production Of Trans-4-Aminocyclopent-2-Ene-1-Carboxylic Acid Derivatives[fr] Production De Dérivés D'Acide Trans-4-Aminocyclopent-2-ène-1-Carboxylique
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
2905143000-叔丁醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:WO-2009042013-A1
优先权日:2007-08-02
标题:Process for the synthesis of e1 activating enzyme inhibitors
专利号:US-2018079755-A1
优先权日:2007-08-02
标 题:Process for the synthesis of e1 activating enzyme inhibitors
专利号:US-2009036678-A1
优先权日:2007-08-02
标题 :Process for the synthesis of E1 activating enzyme inhibitors
专利号:US-2015080573-A1
优先权日:2007-08-02
标题 :Process for the synthesis of e1 activating enzyme inhibitors
专利号:EP-2546256-A2
优先权日:2007-08-02
标 题 :Process for the synthesis of intermediates compounds useful for the preparation of E1 activity activating enzyme inhibitors
专利号:US-2015353555-A9
优先权日:2007-08-02
标题:Process for the synthesis of e1 activating enzyme inhibitors
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Process For The Synthesis Of E1 Activating Enzyme Inhibitors摘要:The Present Invention Provides Processes And Synthetic Intermediates For The Synthesis Of 4-Substituted ((1S,2S,4R)-2-Hydroxy-4-7H-Pyrrolo[2,3-D]Pyrimidin-7-Yl}Cyclopentyl)Methyl Sulfamates, Which Are E1 Activating Enzyme Inhibitors, And Are Useful For The Treatment Of Disorders Of Cell Proliferation, Particularly Cancer, And Other Disorders Associated With E1 Activity.
合成参考文献
参考文献:10.1055/s-0035-1560846
摘要:Synthesis of Pevonedistat. Synfacts. 2015 Nov 17;11(12):1244. doi: 10.1055/s-0035-1560846.
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