CAS: 2834-23-3; Chlorodifluoroaceticanhydride

相似化合物

401-67-2 1514-87-0 383-62-0

上下游产品

CAS号76-04-0 一氯二氟乙酸 | CAS号3330-14-1 1,1,1,2,2,3,3-七... | CAS号1644-11-7 2-全氟丙氧基全氟丙基三氟乙烯基醚 | CAS号140229-79-4 1-chloro-1,1,3,... | CAS号219296-24-9 3-(氯二氟乙酰基)咪唑并[1... | CAS号116-14-3 四氟乙烯 | CAS号75-68-3 1-氯-1,1-二氟乙烷 | CAS号75-38-7 偏氟乙烯 | CAS号2317-91-1 1-氯-1-氟乙烯 | CAS号76-14-2 1,2-二氯四氟乙烷 | CAS号79-35-6 1,1-二氯-2,2-二氟乙烯

二氟氯乙酸置于phosphorus Pentoxide体系中,化学反应生成氯二氟乙酸酐
参考文献:Yagupol'Skii,L.M.; Korin'Ko,V.A.,Journal Of General Chemistry Of The Ussr,1967,Vol. 37,P. 1637-1640
标题:Yagupol'Skii,L.M.; Korin'Ko,V.A.,Journal Of General Chemistry Of The Ussr,1967,Vol. 37,P. 1637-1640

专利信息

专利号:US-6140515-A
优先权日:1997-09-24
标题 :Process of making 3-aryloxy, 4-aryl furan-2-ones useful as inhibitors of COX-2
发明人：CHEN CHENG Y; TAN LUSHI; LARSEN ROBERT D
权利人:MERCK & CO INC
摘要:Described is a process of preparing 3-aryl, 4-aryloxy furan-5-ones which are useful as inhibitors of cyclooxygenase-2 (COX-2). Such compounds are useful as anti-inflammatory agents. The process is directed to an asymmetric synthesis which involves: a trisubstituted styrene derivative preparation via Horner-Wadsworth-Emmons reaction and subsequent one pot trifluoromethylation of the allylic alcohol; preparation of the alpha -hydroxyl ketone using Sharpless asymmetric dihydroxylation and Swern oxidation; the esterification of the alpha -hydroxyl ketone with the phenoxy acetic acid; and the Dieckman condensation of the resulting ester.

专利号:US-3963734-A
优先权日:1971-09-17
标 题:Lower alkylsulfonyl 2-amino, 3-nitro pyridines
发明人：DOHERTY GEORGE O P; FUHR KENNETH H
权利人:LILLY CO ELI
摘要:Substituted 1-hydroxy-2-(1,1-difluoroalkyl)-1H-imidazo-(4,5-b)pyridine compounds useful as herbicides; and intermediates useful in the synthesis of these compounds. In addition to exhibiting herbicidal activity, the substituted 1-hydroxy-2-(1,1-difluoroalkyl)-1H-imidazo(4,5-b)pyridine compounds are of low mammalian toxicity.

专利号:US-9328108-B2
优先权日:2011-10-28
标 题 :Process for preparing an intermediate of the macrocyclic protease inhibitor TMC 435
发明人：HORVATH ANDRAS; WUYTS STIJN; DEPRÉ DOMINIQUE PAUL MICHEL; COUCK WOUTER LOUIS J; CUYPERS JOZEF LUDO JAN; HARUTYUNYAN SYUZANNA; BINOT GREGORY FABIEN SEBASTIAN
权利人:JANSSEN PHARMACEUTICALS INC
摘要:The present invention relates to an improved process for preparing (2R,3aR,10Z,11aS,12aR,14aR)-cyclopenta[c]cyclopropa[g][1,6]diazacyclotetradecine-12a(1H)-carboxylic acid, 2,3,3a,4,5,6,7,8,9,11a,12,13,14,14a-tetradecahydro-2-[[7-methoxy-8-methyl-2-[4-(1-methylethyl)-2-thiazolyl]-4-quinolinyl]oxy]-5-methyl-4,14-dioxo-, ethyl ester. This compound is an intermediate in the overall synthesis route of the macrocyclic compound TMC 435. TMC 435 is an inhibitor of NS3/4A protease which plays an important role in the replication of the hepatitis C virus.

专利号:US-4087432-A
优先权日:1974-05-23
标 题 :1H-imidazo(4,5-b)pyridine compounds
发明人：O DOHERTY GEORGE O P; FUHR KENNETH H
权利人:LILLY CO ELI
摘要:Substituted 1-hydroxy-2-(1,1-difluoroalkyl)-1H-imidazo-(4,5-b)pyridine compounds useful as herbicides; and intermediates useful in the synthesis of these compounds. In addition to exhibiting herbicidal activity, the substituted 1-hydroxy-2-(1,1-difluoroalkyl)-1H-imidazo(4,5-b)pyridine compounds are of low mammalian toxicity.

专利号:US-3813408-A
优先权日:1970-03-20
标 题:1h-imidazo(4,5-b)pyridine compounds
发明人：DOHERTY G; FUHR K
权利人:LILLY CO ELI
摘要:SUBSTITUTED 3-HYDROXY-2 - (1,1 - DIFLUOROALKYL) - 1HIMIDAZO(4,5-B)PYRIDINE COMPOUNDS USEFUL AS HERBICIDES; AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF THESE COMPOUNDS. IN ADDITION TO EXHIBITING HERBICIDAL ACTIVITY, THE SUBSTITUTED 1 - HYDROXY-2-(1,1-DIFLUOROALKYL)-1H-IMIDAZO(4,5-B)PYRIDINE COMPOUNDS ARE OF LOW MAMMALIAN TOXICITY.

专利号:US-3968116-A
优先权日:1971-09-17
标 题 :1H-imidazo(4,5-b)pyridine compounds
发明人：DOHERTY GEORGE O P; FUHR KENNETH H
权利人:LILLY CO ELI
摘要:Substituted 1-hydroxy-2-(1,1-difluoroalkyl)-1H-imidazo-(4,5-b)pyridine compounds useful as herbicides; and intermediates useful in the synthesis of these compounds. In addition to exhibiting herbicidal activity, the substituted 1-hydroxy-2-(1,1-difluoroalkyl-1H-imidazo(4,5-b)pyridine compounds are of low mammalian toxicity.