CAS: 20744-39-2; Pyridazin-4-Amine

相似化合物

16401-70-0 29049-45-4 1400764-35-3

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CAS号823-58-5 3,6-二氯哒嗪-4-胺 | CAS号14161-11-6 3,4,5-三氯哒嗪 | CAS号289-80-5 哒嗪 | CAS号53180-76-0 3,5-二氯-4-氨基哒嗪 | CAS号89180-50-7 3,4-二氯-5-氨基哒嗪 | CAS号5469-70-5 3-氨基哒嗪 | CAS号169050-21-9 4-(B°C-氨基)吡嗪 | CAS号169050-20-8 2,2-dimethyl-N-... | CAS号55928-90-0 5-溴-4-吡嗪胺 | CAS号55928-84-2 4-Amino-3-bromo...

📜哒嗪置于氨,氢化钾,Ferric Nitrate,Potassium Permanganate体系中,化学反应 0.34H,以83%的收率获得4-氨基哒嗪
参考文献: 1,1,1-Trifluoro-4-Phenyl-4-Methyl-2-(1H-Pyrrolo[fr] Derives De 1,1,1-Trifluoro-4-Phenyl-4-Methyl-2-(1H-Pyrrolo-2,3-C Pyridin-2-Ylmethyl)Pentan-2-Ole Et Composes Associes En Tant Que Ligands De Glucocorticoides Pour Le Traitement De Maladies Inflammatoires Et De Diabete
标题: 1,1,1-Trifluoro-4-Phenyl-4-Methyl-2-(1H-Pyrrolo[fr] Derives De 1,1,1-Trifluoro-4-Phenyl-4-Methyl-2-(1H-Pyrrolo-2,3-C Pyridin-2-Ylmethyl)Pentan-2-Ole Et Composes Associes En Tant Que Ligands De Glucocorticoides Pour Le Traitement De Maladies Inflammatoires Et De Diabete
摘要:式(I A),(Ib),(Ic)和(Id)的化合物,其中r1,R2,R3,R4,R5和r6分别如本文所定义的式(I A),(Ib),(Ic)和(Id),或其互变异构体,前药,溶剂化合物或盐;含有这些化合物的药物组合物,以及利用这些化合物调节糖皮质激素受体功能的方法,以及利用这些化合物治疗由糖皮质激素受体功能介导或以炎症,过敏或增殖过程为特征的疾病状态或病情的方法.

专利信息

专利号:US-4398044-A
优先权日:1982-04-08
标 题 :Synthesis of acetyl-T-alkanes
发明人：ABDULLA RIAZ F
权利人:LILLY CO ELI
摘要:Acetyl-tertiary-alkanes are prepared by hydrolytic decarboxylation of tertiary-alkanoylacetonitriles with hydrochloric acid.

专利号:US-4411753-A
优先权日:1982-04-08
标 题:Synthesis of 6-t-alkyl-3-pyridazinones
发明人：ABDULLA RIAZ F
权利人:LILLY CO ELI
摘要:A class of 6-t-alkyl-3-pyridazinones are prepared from 3-t-alkanoyl-2-propenoic acids by irradiation with strong light and reaction with hydrazine.

专利号:WO-2024256496-A1
优先权日:2023-06-14
标题 :[1,2,4]-triazolo[4,3-b]pyridazine derivatives useful as a medicament
发明人：ELIE JONATHAN; GEORGE PASCAL; MIEGE FRÉDÉRIC; MEIJER LAURENT
权利人:PERHA PHARMACEUTICALS
摘要:The present invention relates to a compound of formula (I) or any of its pharmaceutically acceptable salt. The present invention further relates to a synthesis process for manufacturing compound of formula (I) or any of its pharmaceutically acceptable salts, comprising at least a step of reacting a compound of formula (II) with an amine of formula (IV) NHR5R6 for example in a molar ratio ranging from 1 to 20 eq, with respect to the compound of formula (II), in an aprotic solvent or without solvent or else in a protic solvent.

专利号:US-9925177-B2
优先权日:2015-01-22
标题:4-methylsulfonyl-substituted piperidine urea compounds
发明人：OSLOB JOHAN; AUBELE DANIELLE; KIM JAE; MCDOWELL ROBERT; SONG YONGHONG; SRAN ARVINDER; ZHONG MIN
权利人:MYOKARDIA INC
摘要:The present invention provides novel 4-methylsulphone-substituted piperidine urea compounds that are useful for the treatment of dilated cardiomyopathy (DCM) and conditions associated with left and/or right ventricular systolic dysfunction or systolic reserve. The synthesis and characterization of the compounds is described, as well as methods for treating DCM and other forms of heart disease.

专利号:US-11123337-B2
优先权日:2015-01-22
标题 :4-methylsulfonyl-substituted piperidine urea compounds
发明人：OSLOB JOHAN; AUBELE DANIELLE; KIM JAE; MCDOWELL ROBERT; SONG YONGHONG; SRAN ARVINDER; ZHONG MIN
权利人:MYOKARDIA INC
摘要:The present invention provides novel 4-methylsulphone-substituted piperidine urea compounds that are useful for the treatment of dilated cardiomyopathy (DCM) and conditions associated with left and/or right ventricular systolic dysfunction or systolic reserve. The synthesis and characterization of the compounds is described, as well as methods for treating DCM and other forms of heart disease.