- 英文名称(R,E)-2-Methyl-6-((5R,10S,13R,14R,17R)-4,4,10,13,14-Pentamethyl-3-Oxo-2,3,4,5,6,10,12,13,14,15,16,17-Dodecahydro-1H-Cyclopenta[a]Phenanthren-17-yl)Hept-2-Enal
- 中文名称灵芝醛A
- IUPAC名称(R,E)-2-methyl-6-((5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-3-oxo-2,3,4,5,6,10,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)hept-2-enal
- 其它别名(24E)-3-Oxolanosta-7,9(11),24-Trien-26-Al; (24E)-3-Oxo-5α-Lanosta-7,9(11),24-Trien-26-Al; (24E)-3-Oxo-5α-Lanosta-7,9(11),24-Triene-26-Al; Ganoderal A; Ganoderma Aldehyde A; Lanosta-7,9(11),24-Trien-26-Al,3-Oxo-, (24E)-; (24E)-3-Oxo-5α-Lanosta-7,9(11),24-Triene-26-Al
- CAS编号104700-98-3
- MFCD编号:MFCD21364031
- 分子式:C30H44O2分子量:436.68
- 产品CID: 85898
- 产品分类天然产物 → 萜类
- 相似结构搜索
- 产品信息参考
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- InChIKey: RHNFCIPJKSUUES-SPFFTVLFSA-N
- InChI=1S/C30H44O2/c1-20(19-31)9-8-10-21(2)22-13-17-30(7)24-11-12-25-27(3,4)26(32)15-16-28(25,5)23(24)14-18-29(22,30)6/h9,11,14,19,21-22,25H,8,10,12-13,15-18H2,1-7H3/b20-9
- 计算化学: 氢键受体数2.0氢键供体数*可旋转键数5.0
专利信息
专利号:US-6726911-B1
优先权日:1999-03-09
标 题 :Biologically active compounds of Ganoderma pfeifferi DSM 13239
发明人:JUELICH WOLF; LINDEQUIST ULRIKE; JANSEN ROLF; MOTHANA RAMZI
权利人:GANOMYCIN
摘要:The present invention relates to novel biologically active compounds from fungi of the species Ganoderma pfeifferi DSM 13239, processes for their preparation, and their use. From the fruit body and mycelium of the species Ganoderma pfeifferi DSM 13239, extracts can be obtained which have antimicrobial activity and are suitable as preserving agents, for pharmaceutical and cosmetic preparations, for controlling infections, and for use in fish breeding. Antimicrobially active substances called ganomycins having activity against multiresistant germs are isolated from the extracts. The total synthesis of the ganomycins and their derivatization enables their use an antibiotics.