38624-58-7 = 926-66-9 [标题:Reaction Conditions 标题:The Thermal Decarboxylation Of β-Alkoxycrotonic Acids. A New Synthesis Of Isopropenyl Ethers 作者:Le Noble,W. J.; Crean,P. J. 参考文献:Journal Of Organic Chemistry 日期:1962 卷标:27 页码:3875-8]
126-84-1 = 926-66-9 反应条件:1.1 Reagents: Quinoline,P-Toluenesulfonic Acid 标题:Polyene Compounds. Viii. Reactions Of Some Acetals With Unsaturated Esters 作者:Mikhailov,B. M.; Povaroy,L. S. 参考文献:Zhurnal Obshchei Khimii 日期:1959 卷标:29 页码:2079-83]
= 926-66-9 [标题:Reaction Conditions 标题:Method For Preparation Of 2-Ethoxypropene Via Pyrolysis 参考文献:China]
= 926-66-9 [标题:Reaction Conditions 标题:Preparation Of Saccharide Derivatives Of Quinazolines As Protein Tyrosine Kinase Inhibitors 参考文献:China]
= 926-66-9 [标题:Reaction Conditions 标题:Method For Preparation Of Unsaturated Ketones 参考文献:Germany]
= 926-66-9 [标题:Reaction Conditions 标题:17O Nmr Spectra Of Vinyl Ethers 作者:Taskinen,Esko; Hellman,Jaakko 参考文献:Magnetic Resonance In Chemistry 日期:1994 卷标:32(6) 页码:353-7]
= 926-66-9 [标题:Reaction Conditions 标题:A Catalyst For The Manufacture Of Methyl And Ethyl Isopropenyl Ether 参考文献:German Democratic Republic]
= 926-66-9 [标题:Reaction Conditions 标题:A Catalyst For The Manufacture Of Methyl And Ethyl Isopropenyl Ethers 参考文献:German Democratic Republic]
126-84-1 = 926-66-9 反应条件:1.1 160 °C 标题:Synthesis Of 2-Ethoxypropene 作者:Cui,Wei; Huang,Wei 参考文献:Shanghai Huagong 日期:2004 卷标:29(11) 页码:24-25]
126-84-1 = 926-66-9 反应条件:1.1 2.0 Atm,140 °C 标题:Synthesis Of 2-Alkoxypropenes 参考文献:China]
126-84-1 = 926-66-9 反应条件:1.1 0.25 Mpa,300 °C 标题:Preparation Method Of 2-Alkoxypropene In Presence Of Modified Y-Type Molecular Sieve Catalyst And Alkaline Carrier 参考文献:China]
126-84-1 = 926-66-9 反应条件:1.1 Reagents: Benzoic Acid,Phthalic Anhydride,1,2-Dimethoxyethane,Pyridine; 125 - 135 °C1.2 15 Min,125 - 135 °C 标题:Preparation Of 2-Alkoxypropene From 2,2-Dialkoxypropane 参考文献:China]
126-84-1 = 926-66-9 反应条件:1.1 Reagents: P-Toluenesulfonic Acid 标题:Preparation Of 2-Ethoxypropene By Liquid Phase Pyrolysis Of 2,2-Diethoxypropane 作者:Dai,Liyan; Chen,Yingqi 参考文献:Zhongguo Yiyao Gongye Zazhi 日期:2001 卷标:32(5) 页码:229-230]
= 926-66-9 反应条件:1.1 Rt -> 170 °C; 1.12 H,170 °C 标题:Process For Preparing Ethoxy Propene 参考文献:China]
= 926-66-9 反应条件:1.1 Catalysts: Sodium Hydroxide; 1.2 H,135 - 150 °C 标题:Green Preparation Of 2-Ethoxypropene 参考文献:China]
= 926-66-9 [标题:Reaction Conditions 标题:Bis(Cyclopentadienyl)Dimethyltitanium 作者:Petasis,Nicos A.; Morshed,M. Monzur; Ahmad,M. Syarhabil; Hossain,M. Mahmun; Trippier,Paul C. 参考文献:E-Eros Encyclopedia Of Reagents For Organic Synthesis 日期:2012 卷标:1 页码:1-13]
126-84-1 = 926-66-9 反应条件:1.1 Reagents: Aluminum Chloride Solvents: 1-Butyl-3-Methylimidazolium Chloride; 4 H,130 °C 标题:Ionic Liquids As Catalytic Green Solvents For Cracking Reactions 作者:Wang,Yong; Li,Haoran; Wang,Congmin; Jiang,Hui 参考文献:Chemical Communications (Cambridge 日期:2004 卷标:(17) 页码:1938-1939]
38624-58-7 = 926-66-9 [标题:Reaction Conditions 标题:A Convenient And Stereoselective Synthesis Of (3Z,5Z)-5-Fluorotetradecadien-1-Yl Acetate,A Fluorinated Analog Of The Sex Pheromone Of The Carpenterworm Prionoxistus Robiniae (Peck) 作者:Alcazar,A.; Camps,F.; Coll,J.; Fabrias,G.; Guerrero,A. 参考文献:Synthetic Communications 日期:1985 卷标:15(9) 页码:819-27
3-乙氧基-2-丁炔羧酸乙酯置于sodium Hydroxide体系中,化学反应生成 2-乙氧基丙烯 参考文献:Dolliver Et Al.,Journal Of The American Chemical Society,1938,Vol. 60,P. 441 标题:Dolliver Et Al.,Journal Of The American Chemical Society,1938,Vol. 60,P. 441
专利号:WO-2012059797-A1 优先权日:2010-11-04 标题 :Process for synthesis of (s) - pregabalin 发明人:ROY BHAIRAB NATH; SINGH GIRIJ PAL; LATHI PIYUSH SURESH; AGRAWAL MANOJ KUNJABIHARI; MITRA RANGAN; RUPNAWAR MANOJ DATTATRAYA 权利人:LUPIN LTD; ROY BHAIRAB NATH; SINGH GIRIJ PAL; LATHI PIYUSH SURESH; AGRAWAL MANOJ KUNJABIHARI; MITRA RANGAN; RUPNAWAR MANOJ DATTATRAYA 摘要:Improved process for the synthesis of (S)-pregabalin having more than 99% ee through (S) 3-cyano-5-methyl-hexanoic acid has been developed. In addition to above, a novel process for resolution of ( RS ) - 3-cyano-5-methyl-hexanoic acid through diastereomeric salt formation with cinchonidine to obtain ( S ) - 3-cyano-5-methyl-hexanoic acid in high yield and high optical purity has been developed and furthermore process for recovery/ reuse of cinchonidine is also developed to improve the overall process efficiency.
专利号:US-11794179-B2 优先权日:2016-08-24 标 题 :Synthesis and characterization of metathesis catalysts 发明人:JOHNS ADAM M 权利人:UMICORE AG & CO KG 摘要:This invention relates generally to olefin metathesis catalysts, to the preparation of such compounds, compositions comprising such compounds, methods of using such compounds, and the use of such compounds in the metathesis of olefins and in the synthesis of related olefin metathesis catalysts. The invention has utility in the fields of catalysis, organic synthesis, polymer chemistry, and in industrial applications such as oil and gas, fine chemicals and pharmaceuticals.
专利号:US-8026383-B2 优先权日:2001-07-06 标题:Process for the preparation of intermediates useful in the synthesis of statin derivatives 发明人:OEHRLEIN REINHOLD; BAISCH GABRIELE; END NICOLE; BURKHARDT STEPHAN; STUDER MARTIN 权利人:BASF SE 摘要:The invention relates to novel synthesis methods for the preparation of statin derivatives, which methods proceed by way of a key intermediate of formula I n nwherein X is halogen, acyloxy, activated hydrocarbyloxy, activated hydrocarbylthio or —N(CH 3 )OCH 3 , R a is a hydroxy-protecting group and R b is a carboxy-protecting group, and, as well as to the compound of formula I, to further new intermediates and methods for their preparation by Friedel-Crafts acylation.
专利号:WO-2025125573-A1 优先权日:2023-12-14 标 题 :Manufacture of alpha, beta, gamma, delta or beta, gamma, delta di-unsaturated ketones carrying a terminal carboxyl group 发明人:AQUINO FABRICE; BONRATH WERNER; GOETZINGER ALISSA; HAESS STEFAN; LEHMANN HAJO; MEDLOCK JONATHAN ALAN; PACE FRANCESCO; SORIANO DOMENICO; STEMMLER RENÉ TOBIAS 权利人:DSM IP ASSETS BV 摘要:The present invention relates to synthesis of carboxy group terminated di-unsaturated ketones having C=C double bonds at the α,β and γ,δ position or at the β,γ and γ,δ position relative to the carbonyl carbon atom. These ketones can be obtained easily and in few steps from respective alkynols having a terminal carboxyl group. These ketones are important key building block for the synthesis of derivatives of isoprenoids, especially of vitamin E.
专利号:WO-2025125574-A1 优先权日:2023-12-14 标 题 :Manufacture of allylic alcohols carrying a terminal carboxyl group via ethynylation and lindlar hydrogenation 发明人:AQUINO FABRICE; BONRATH WERNER; GOETZINGER ALISSA; HAESS STEFAN; LEHMANN HAJO; MEDLOCK JONATHAN ALAN; PACE FRANCESCO; SORIANO DOMENICO; STEMMLER RENÉ TOBIAS 权利人:DSM IP ASSETS BV 摘要:The present invention relates to synthesis of specific allylic alcohols having terminal carboxyl groups based on steps of ethynylation and hydrogenation in the presence of a Lindlar catalyst. These allylic alcohols are particularly useful to offer pathways to syntheses of isophytol or tocopherols having a terminal carboxyl group by a very small number of reactions steps.
专利号:US-8987478-B2 优先权日:2011-12-09 标 题:Process for the preparation of a statin precursor 发明人:DE LANGE BEN; HEEMSKERK DENNIS; BESSEMBINDER KARIN HENDERIKA MARIA 权利人:DSM SINOCHEM PHARM NL BV 摘要:The present invention relates to a process for the preparation of a precursor for the synthesis of hexanoic acid derived statins and to the use of said precursor in the manufacture of a medicament.
参考标题:Synthesis Of Piperidine Derivatives By Rhodium- Catalyzed Tandem Reaction OfN-Sulfonyl-1,2,3-Triazole And Vinyl Ether 作者:Sisi Yu,Yuehui An,Wenlin Wang,Ze-Feng Xu,Chuan-Ying Li |发布日期:2018.6.5 摘要:A Chemoselective Tandem Reaction Of 4‐acyloxymethylene‐1‐sulfonyl‐1,2,3‐triazole And Vinyl Ether Was Reported, Producing Polysubstituted Piperidine Derivatives In Up To 96% Yield. The Key Intermediate N‐sulfonyl 1‐azadiene Generated By Migration Of The Oac Group To The α‐imino Rhodium Carbene Was Isolated And A Plausible Mechanism Was Proposed. Several Related Ring Systems Were Constructed From The
合成参考文献
摘要:Carbery, D., Science of Synthesis Knowledge Updates, (2010) 3, 156.