CAS: 68141-13-9; 6-(Tert-Butyl)Quinoline

该化合物是一种有机化合物,其特征是其quinoline结构,包括一个有引信的苯和环.六点的叔丁基化合物组增强了其脂性,可以影响其在有机溶剂中的活性和溶解性.该化合物一般是黄色至褐色固体,以其在有机合成和荧光探测器中的潜在应用而著称.其分子式反映了一个相对复杂的结构,有助于其独特的化学特性.六点-丁基酮可展示出有趣的光物理特性,使其在各个领域,包括材料科学和医药化学领域有用.此外,其稳定性和回性可以受三点-丁基化合物组的存在的影响,这可能影响其与其他化学物种的相互作用.应当参考安全数据,以便处理和储存,如同任何化学物质一样,确保采取适当的预防措施.

结构式图片

相似化合物

135-79-5 1393442-59-5 19655-60-8

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CAS号769-92-6 4-叔丁基苯胺 | CAS号127-68-4 间硝基苯磺酸钠 | CAS号56-81-5 甘油 | CAS号3282-56-2 1-叔丁基-4-硝基苯 | CAS号75413-98-8 6-(tert-butyl)-... | CAS号75414-04-9 6-(tert-butyl)-...

合成工艺路线路线简述

    1-特-丁基-4-硝基苯置于arsenic(V) Oxide,硫酸体系中,化学反应生成 6-(1,1-二甲基乙基)喹啉
    参考文献:Hoenel,Michael; Vierhapper,Friedrich W.,Journal Of The Chemical Society. Perkin Transactions I,1980,P. 1933-1939
    标题:Hoenel,Michael; Vierhapper,Friedrich W.,Journal Of The Chemical Society. Perkin Transactions I,1980,P. 1933-1939

    海关参考信息

    专利信息


    专利号:US-11661406-B2
    优先权日:2018-08-13
    标 题 :Method for producing intermediate useful for synthesis of SGLT inhibitor
    发明人:LI QING RI; YOON HEE KYOON
    权利人:DAEWOONG PHARMACEUTICAL CO LTD
    摘要:A method of preparing an intermediate useful for the synthesis of a diphenylmethane derivative that can be used as an SGLT inhibitor is described. A method of synthesizing a compound of Formula 7 can address problems of existing synthesis processes requiring the synthesis of the Grignard reagent and management of related substances. In addition, the method can minimize the generation of related substances, and thus does not require reprocessing of reaction products, thereby simplifying the process. Accordingly, the production yield of a diphenylmethane derivative can be maximized.

    专利号:US-9988488-B2
    优先权日:2013-03-26
    标 题:Catalyst for poly(lactide) synthesis and uses thereof
    发明人:CHAKRABORTY DEBASHIS; GHOSH SWARUP; RAMKUMAR VENKATACHALAM
    权利人:INDIAN INSTITUTE OF TECH MADRAS
    摘要:A catalysts for poly(lactide) synthesis having the structure of Formula I: n nwherein R 1 and R 2 is, independently, C 1 -C 6 alkoxy, and R 3 arylalkyl or substituted phenyl are disclosed. Method of synthesizing the catalysts and method of using the catalysts to prepare poly(lactides) and compositions comprising the catalyst are also disclosed.

    专利号:US-10995078-B2
    优先权日:2013-03-13
    标 题:Compounds and compositions for inhibition of FASN
    发明人:BAIR KENNETH W; LANCIA JR DAVID R; LI HONGBIN; LOCH JAMES; LU WEI; MARTIN MATTHEW W; MILLAN DAVID S; SCHILLER SHAWN E R; TEBBE MARK J
    权利人:FORMA THERAPEUTICS INC
    摘要:The present invention relates to compounds and composition for inhibition of FASN, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:

    专利号:US-11066447-B2
    优先权日:2016-08-08
    标 题:Aureobasidium derivatives and methods of synthesis
    发明人:WUTS PETER; ELHAMMER AKE P
    权利人:AUREOGEN BIOSCIENCES INC; AUEROGEN BIOSCIENCES INC
    摘要:In general, the invention relates to AbA derivatives that are useful for treating infection. These novel compounds are shown to be effective in treating various fungal infections. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various fungal infections.

    专利号:US-2021292291-A1
    优先权日:2018-08-13
    标 题:Method for producing intermediate useful for synthesis of sglt inhibitor

    专利号:US-10889574-B2
    优先权日:2016-06-17
    标 题 :Method for producing diphenylmethane derivative
    发明人:YOON HEE-KYOON; PARK SE-HWAN; YOON JI-SUNG; CHOI SOONGYU; SEO HEE JEONG; PARK EUN-JUNG; KONG YOUNGGYU; SONG KWANG-SEOP; KIM MIN JU; PARK SO OK
    权利人:DAE WOONG PHARMA; GREEN CROSS CORP
    摘要:The present invention relates to an improved method for producing a diphenylmethane derivative which is effective as a sodium-dependent glucose cotransporter (SGLT) inhibitor, the method being carried out by means of a convergent synthesis method in which each major group is separately synthesized and then coupled. As such, in comparison to a linear synthesis method disclosed in existing documents, the synthesis pathway is compact and yield can be increased, and risk factors inherent in the linear synthesis pathway can be reduced. Furthermore, the crystal form of the compound produced according to the method has superb physicochemical characteristics, and thus can be effectively utilized in fields such as pharmaceutical manufacturing.
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    合成参考文献


    摘要:Zeitler, K., Science of Synthesis, (2019) , 321.
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