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CAS号769-92-6 4-叔丁基苯胺 | CAS号127-68-4 间硝基苯磺酸钠 | CAS号56-81-5 甘油 | CAS号3282-56-2 1-叔丁基-4-硝基苯 | CAS号75413-98-8 6-(tert-butyl)-... | CAS号75414-04-9 6-(tert-butyl)-...1-特-丁基-4-硝基苯置于arsenic(V) Oxide,硫酸体系中,化学反应生成 6-(1,1-二甲基乙基)喹啉
参考文献:Hoenel,Michael; Vierhapper,Friedrich W.,Journal Of The Chemical Society. Perkin Transactions I,1980,P. 1933-1939
标题:Hoenel,Michael; Vierhapper,Friedrich W.,Journal Of The Chemical Society. Perkin Transactions I,1980,P. 1933-1939
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专利信息
专利号:US-11661406-B2
优先权日:2018-08-13
标 题 :Method for producing intermediate useful for synthesis of SGLT inhibitor
发明人:LI QING RI; YOON HEE KYOON
权利人:DAEWOONG PHARMACEUTICAL CO LTD
摘要:A method of preparing an intermediate useful for the synthesis of a diphenylmethane derivative that can be used as an SGLT inhibitor is described. A method of synthesizing a compound of Formula 7 can address problems of existing synthesis processes requiring the synthesis of the Grignard reagent and management of related substances. In addition, the method can minimize the generation of related substances, and thus does not require reprocessing of reaction products, thereby simplifying the process. Accordingly, the production yield of a diphenylmethane derivative can be maximized.
专利号:US-9988488-B2
优先权日:2013-03-26
标 题:Catalyst for poly(lactide) synthesis and uses thereof
发明人:CHAKRABORTY DEBASHIS; GHOSH SWARUP; RAMKUMAR VENKATACHALAM
权利人:INDIAN INSTITUTE OF TECH MADRAS
摘要:A catalysts for poly(lactide) synthesis having the structure of Formula I: n nwherein R 1 and R 2 is, independently, C 1 -C 6 alkoxy, and R 3 arylalkyl or substituted phenyl are disclosed. Method of synthesizing the catalysts and method of using the catalysts to prepare poly(lactides) and compositions comprising the catalyst are also disclosed.
专利号:US-10995078-B2
优先权日:2013-03-13
标 题:Compounds and compositions for inhibition of FASN
发明人:BAIR KENNETH W; LANCIA JR DAVID R; LI HONGBIN; LOCH JAMES; LU WEI; MARTIN MATTHEW W; MILLAN DAVID S; SCHILLER SHAWN E R; TEBBE MARK J
权利人:FORMA THERAPEUTICS INC
摘要:The present invention relates to compounds and composition for inhibition of FASN, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:
专利号:US-11066447-B2
优先权日:2016-08-08
标 题:Aureobasidium derivatives and methods of synthesis
发明人:WUTS PETER; ELHAMMER AKE P
权利人:AUREOGEN BIOSCIENCES INC; AUEROGEN BIOSCIENCES INC
摘要:In general, the invention relates to AbA derivatives that are useful for treating infection. These novel compounds are shown to be effective in treating various fungal infections. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various fungal infections.
专利号:US-2021292291-A1
优先权日:2018-08-13
标 题:Method for producing intermediate useful for synthesis of sglt inhibitor
专利号:US-10889574-B2
优先权日:2016-06-17
标 题 :Method for producing diphenylmethane derivative
发明人:YOON HEE-KYOON; PARK SE-HWAN; YOON JI-SUNG; CHOI SOONGYU; SEO HEE JEONG; PARK EUN-JUNG; KONG YOUNGGYU; SONG KWANG-SEOP; KIM MIN JU; PARK SO OK
权利人:DAE WOONG PHARMA; GREEN CROSS CORP
摘要:The present invention relates to an improved method for producing a diphenylmethane derivative which is effective as a sodium-dependent glucose cotransporter (SGLT) inhibitor, the method being carried out by means of a convergent synthesis method in which each major group is separately synthesized and then coupled. As such, in comparison to a linear synthesis method disclosed in existing documents, the synthesis pathway is compact and yield can be increased, and risk factors inherent in the linear synthesis pathway can be reduced. Furthermore, the crystal form of the compound produced according to the method has superb physicochemical characteristics, and thus can be effectively utilized in fields such as pharmaceutical manufacturing.