CAS: 54751-01-8; 4-(Bromomethyl)Pyridine

相似化合物

73870-24-3 4916-55-6 843673-58-5

上下游产品

pyridine-4-methanol picoline pyridine-4-carboxylic acid 4-bromomethyl pyridine hydrobromide(1-{[1-Phenyl-meth-(E)-ylidene]-amino}-2-pyridin-4-yl-ethyl)-phosphonic acid diethyl ester pyridine4-(diethylphosphono)methylpyridine Triphenyl(4-picolyl)phosphoniumbromid 3-methyl-3-pyridin-4-ylmethyl-1-(toluene-4-sulfonyl)-pyrrolidin-2-one

📜4-甲基吡啶置于溴体系中,化学反应 1.0H,反应生成 4-溴甲基吡啶
参考文献:一种4-甲氧基甲基吡啶的合成方法
标题:一种4-甲氧基甲基吡啶的合成方法
摘要:本发明涉及有机化学领域,特别是一种4‑甲氧基甲基吡啶的合成方法,以4‑甲基吡啶为原料,通过溴化反应得到4‑溴‑甲基吡啶;所述4‑溴‑甲基吡啶与三甲胺反应得到(4‑吡啶甲基)三甲基溴化铵;将所述(4‑吡啶甲基)三甲基溴化铵溶于甲醇,再加入甲醇钠,在氮气下加热回流1H,得到4‑甲氧基甲基吡啶.采用上述合成方法后,本发明以4‑甲基吡啶为原料,经溴化反应得到4‑溴‑甲基吡啶,三甲胺反应得到(4‑吡啶甲基)三甲基溴化铵,最后与甲醇钠反应得到4‑甲氧基甲基吡啶.本发明的合成方法总收率高,原料价格便宜,反应时间短,条件温和,工艺操作简单.

专利信息

专利号:US-4500535-A
优先权日:1979-10-15
标 题:Method of regulating the immune response with pyridine derivatives
发明人：LOMBARDINO JOSEPH G; HARBERT CHARLES A
权利人:PFIZER
摘要:A series of 4-(2-carboxymethylthiomethyl)pyridines and related compounds, and their pharmaceutically acceptable salts, are disclosed as having immunoregulatory activity. Preferred compounds include 4-(2-carboxymethylthiomethyl)pyridine [alternatively named 2-(4-picolylthio)acetic acid] and (C 1 -C 4 )alkyl esters thereof, and 4-(1-formylmethylthiomethyl)-pyridine [alternatively named 2-(4-picolylthio)acetaldehyde] and bis(C 1 -C 4 )alkyl or cyclic acetals thereof. These acids, esters, aldehydes and acetals also have utility as intermediates in the synthesis of the corresponding 4-(2-hydroxyethylthiomethyl)pyridines.

专利号:US-8895741-B2
优先权日:2003-06-03
标 题:Process for the synthesis of biaryl oxazolidinones
发明人：WU YUSHENG; CHEN SHILI; CHEN YI; HANSELMANN ROGER; LOU RONGLIANG; ZHOU JIACHENG
权利人:WU YUSHENG; CHEN SHILI; CHEN YI; HANSELMANN ROGER; LOU RONGLIANG; ZHOU JIACHENG; MELINTA THERAPEUTICS INC
摘要:The present invention relates to processes for the preparation of biaryl oxazolidinones. These compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.

专利号:US-10730037-B2
优先权日:2015-12-25
标题:Compound and method for manufacturing organic material
发明人：MIYAZAWA TAKASHI; SAKAGUCHI KEN-ICHI
权利人:TOYO GOSEI CO LTD
摘要:Synthesis of organic compounds that has chirality is an important technique in the fields of pharmaceuticals, agrichemicals, health foods and the like. However, raw materials of a catalyst used for the synthesis of such compounds are expensive, and the synthesis needs many steps, so that it is difficult to reduce the cost. Linking a catalyst center to a polymer chain or a resin through an organic group enables to use the catalyst repeatedly and produce a chiral compound at low cost.

专利号:US-9562037-B2
优先权日:2014-02-26
标题:Synthesis and use of amine-containing flavonoids as potent anti-leishmanial agents
发明人：CHOW LARRY MING-CHEUNG; CHAN WILLIAM TAK HANG; CHAN KIN-FAI; WONG IRIS LAI KING; KAN WING-YIU
权利人:UNIV HONG KONG POLYTECHNIC
摘要:The present invention relates to novel series of amine-containing flavonoids and compositions containing the compounds, as well as the synthesis and the use of the same. The invention also relates to methods of treatment and prevention of diseases, in particular, parasitic infections including Leishmaniasis, comprising administration of the compounds.

专利号:US-2010022772-A1
优先权日:2003-06-03
标 题:Process for the synthesis of biaryl oxazolidnones

专利号:US-7371852-B2
优先权日:2003-01-22
标 题 :Alkyl-linked nucleotide compositions
发明人：HARDEMAN KLASS P; HALL STEVEN E; WARE ROY W; HINKLEY LINDSAY A; JENKS MATTHEW G
权利人:SERENEX INC
摘要:Alkyl-linked nucleotide non-homogeneous solid supports and nucleotide affinity media comprising an alkyl-linked nucleotide are provided. The linker is generally a hydrophobic linker that can be a 3, 4, 5, 6, 7, 8, 9, 10, or a longer carbon chain. Also included in the invention are methods for synthesis of an alkyl-linked nucleotide, nucleotide affinity media and methods of use thereof for affinity chromatography and screening methods.