专利号:US-2018312463-A1 优先权日:2015-10-22 标题:Synthesis of Cyclohexane Carboxamide Derivatives Useful as Sensates in Consumer Products 发明人:YELM KENNETH EDWARD; WOS JOHN AUGUST; BUNKE GREGORY MARK; FREDERICK HEATH; HAUGHT JOHN CHRISTIAN; HOKE STEVEN HAMILTON; SREEKRISHNA KOTI TATACHAR; LIN YAKANG 权利人:PROCTER & GAMBLE 摘要:Synthesis methods to produce a series of carboxamides built off of an (S)-2-amino acid backbone or an (R)-2-amino acid backbone, depending upon the desired diastereomer of the end product.
专利号:US-6309842-B1 优先权日:1996-12-03 标 题:Use of modified tethers in screening compound libraries 发明人:DOWER WILLIAM J; GATES CHRISTIAN M; HEINKEL GREGORY L; LALONDE GUY; MATTHEAKIS LARRY C; PADDON CHRISTOPHER J; SCHATZ PETER J 权利人:GLAXO WELLCOME INC 摘要:The invention provides methods for screening libraries of complexes for compounds having a desired property, especially, the capacity to agonize, bind to, or antagonize a cellular receptor. The complexes in such libraries comprise a compound under test, a tag recording at least one step in synthesis of the compound, and a tether susceptible to modification by a reporter molecule. Modification of the tether is used to signify that a complex contains a compound having a desired property. The tag can be decoded to reveal at least one step in the synthesis of such a compound.
专利号:US-12162853-B2 优先权日:2018-10-22 标题:Synthesis of esuberaprost prodrugs 发明人:BATRA HITESH; GUO LIANG 权利人:UNITED THERAPEUTICS CORP 摘要:Provided are novel prodrugs of esuberaprost and pharmaceutical compositions thereof, as well as methods of making and methods of using these prodrugs.
专利号:US-2024052097-A1 优先权日:2021-02-08 标题 :Synthesis of peg-based thiol-norbornene hydrogels with tunable hydroylitic degradation properties 发明人:LIN CHIEN-CHI; LIN FANG-YI 权利人:UNIV INDIANA TRUSTEES 摘要:Methods for synthesizing a hydrogel having tunable hydrolylic degradation kinetics according to certain embodiments include synthesizing a norborene-functionalized polyethylene glycol macromer having an ester linkage between a polyethylene glycol domain of the macromer and a norbornene domain of the macromer and having a carboxyl group on the norbornene; and reacting a quantity of such macromers with a quantity of dithiol molecules by an ultraviolet-initiated photo-gelation reaction to yield a hydrogel. Such macromers and such hydrogels form additional aspects of the disclosure, as do a wide variety of methods for tuning and for using such hydrogels.
专利号:US-7060678-B2 优先权日:2003-08-08 标 题:Peptides comprising furanoid sugar amino acids for the treatment of cancer 发明人:PRASAD SUDHANAND; CHAKRABORTY TUSHAR KANTI; MATHUR ARCHNA; JAGGI MANU; KUNWAR AJIT CHAND; MUKHERJEE RAMA; BURMAN ANAND C 权利人:DABUR RES FOUNDATION 摘要:Anticancer peptides which incorporate furanoid sugar amino acids and compositions made using these peptides are described. Methods for synthesis of the peptides and for preparing the furanoid sugar amino acids are disclosed. The peptides and compositions made using the peptides have pharmacological applications of these peptides especially in the treatment and prevention of cancer and tumors.
专利号:US-6906158-B2 优先权日:2003-03-13 标 题 :Compositions and methods of vinyl oxazolone polymerization 发明人:TULLY DAVID 权利人:IRM LLC 摘要:This invention provides novel methods for synthesis of narrow polydispersity oxazolone-containing polymers via nitroxide-mediated living free radical polymerization, as well as the products and derivatives thereof.
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合成参考文献
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