CAS: 27427-92-5; Pyrimidine-2-Carbaldehyde

相似化合物

14080-23-0 31519-62-7 34253-03-7

上下游产品

嘧啶-2-羧酸 Pyrimidine-2-Carboxylic Acid 31519-62-7
2-羟甲基嘧啶 2-Pyrimidinemethanol 42839-09-8
2-氰基嘧啶 2-Cyanopyrimidine 14080-23-0
2-嘧啶甲酸甲酯 Pyrimidine-2-Carboxylic Acid Methyl Ester 34253-03-7

嘧啶-2-羧酸置于selenium(Iv) Oxide,Sodium Tetrahydroborate,硫酸体系中,用 1,4-二氧六环,乙醇 用作溶剂,化学反应 11.0H,反应生成2-嘧啶甲醛
参考文献:带有三个伪嘧啶中位取代基的不对称锌卟啉衍生物及其对h2的光敏作用
标题:带有三个伪嘧啶中位取代基的不对称锌卟啉衍生物及其对h2的光敏作用
摘要:合成了新的不对称锌卟啉衍生物(znpy-5和znpy-6),其介位带有一个苯甲酸和三个带有两个位于不同位置的n原子的假嘧啶,并用作负载pt的gc 3 N 4( Pcn).相比于模拟(znpy-1轴承一种苯甲酸和三个苯基内消旋-位取代基),Znpy-5和znpy-6显示出在可见光下(显著增强的在pcn光敏λ >=420纳米)的照明.特别地,Znpy-5 / Pcn和znpy-6 / Pcn展览ħ 2的418和585微摩尔ħ进化活动-1,这对应于8845和12 381ħ转换数(ton)-1,分别.这两个值都好于(316μmolh-1)znpy-1 / Pcn,其ton为6687 H-1.此外,Znpy-5 / Pcn和znpy-6 / Pcn在420 Nm单色光下的表观量子产率分别为32.6%和33.1%,这远高于znpy-1 / Pcn的量子产率(10.6%).与znpy-5相比,Znp
Doi:10.1039/d0Nj02056G

专利信息

专利号:US-2007293456-A9
优先权日:2004-12-30
标题:Method for the synthesis of 3-substituted indolizine and benzoindolizine compounds
发明人：HAYFORD ANTHONY; KALOKO JOSEPH
权利人:HAYFORD ANTHONY; KALOKO JOSEPH
摘要:A method of making a compound of Formula I: n n ncomprises reacting a compound of Formula II n n nwith a compound such as R 1 OH or R 1 SH, to produce said compound of Formula I. Compounds of Formula I are useful, among other things, as dyes, spectral sensitizers, glycosidase inhibitors, and as antibacterial, antiviral, and anti-inflammatory agents.

专利号:US-11629150-B2
优先权日:2016-07-01
标题:Synthesis of N-(heteroaryl)-pyrrolo[3,2-d]pyrimidin-2-amines
发明人：SMITH ALEXANDER; WHITE HANNAH S; TAVARES FRANCIS XAVIER; KRASUTSKY SERGIY; CHEN JIAN-XIE; DORROW ROBERTA L; ZHONG HUA
权利人:G1 THERAPEUTICS INC
摘要:This invention is in the area of synthesizing pyrimidine-based compounds useful in the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.

专利号:WO-2004087679-A1
优先权日:2003-04-01
标 题 :2, 4, 6-trisubstituted pyrimidine derivatives useful for the treatment of neoplastic and autoimmune diseases
发明人：OBRECHT DANIEL; ERMERT PHILIPP; LUTHER ANATOL; EBERLE MARTIN; BACHMANN FELIX
权利人:APONETICS AG; OBRECHT DANIEL; ERMERT PHILIPP; LUTHER ANATOL; EBERLE MARTIN; BACHMANN FELIX
摘要:The invention relates to substituted pyrimidines of formula (I) wherein V represents a bond or CR6R7, W represents a bond, NR8 or oxygen, X represents sulfur, or nitrogen substituted by hydrogen or R5, Y represents -CH2-, -CH2CH2-, -CO- or -CS-, R1 represents unsubstituted or substituted aryl or heteroaryl, and the substituents R2, R3, R4, R5, R6, R7 and R8 have the meanings given in the specification. These compounds are selectively inducing apoptosis in cancer cells and can be used for the treatment of neoplastic and autoimmune diseases. The invention relates also to methods of synthesis of such compounds, to their use as medicaments, to pharmaceutical compositions containing same, and to methods of treatment of neoplastic and autoimmune diseases using such compounds of formula (I) or of pharmaceutical compositions containing same.

专利号:US-8138272-B2
优先权日:2006-05-22
标 题:Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds
发明人：KONRADI ANDREI W; SMITH JENIFER L
权利人:KONRADI ANDREI W; SMITH JENIFER L; ELAN PHARM INC
摘要:This invention provides an improved synthesis of polymer conjugates of formula (I), n nof agricultural, therapeutic, and food additive compounds. In particular, a process is described for the preparation of conjugates by treating primary or secondary alcohol substituents of active compounds with polymeric nucleophiles using “Mitsunobuâ€? or related reaction conditions.

专利号:US-9845282-B1
优先权日:2016-08-12
标题 :Palladium catalyzed synthesis of ester compounds
发明人：EL ALI BASSAM M; IBRAHIM MANSUR B; SULEIMAN RAMI K
权利人:UNIV KING FAHD PET & MINERALS
摘要:A catalytic process for synthesizing an ester compound, and a catalytic process for synthesizing an amide compound, wherein a solid-supported palladium catalyst is used to catalyze an alkoxycarbonylation reaction of an aryl halide to form the ester compound, or to catalyze an aminocarbonylation reaction of an aryl halide to form the amide compound. Various embodiments of each of the processes are also provided.

专利号:US-2009247732-A1
优先权日:2003-11-04
标 题 :Synthesis of glycopeptides with superior pharmacokinetic properties
发明人：DUFFIELD JONATHAN; MARBY KENNETH; O'HARE SEAN; HWANG CHAN-KOU; ICHIKAWA YOSHITAKA
权利人:OPTIMER PHARMACEUTICALS INC
摘要:The present invention relates to novel glycopeptides having improved pharmacokinetic properties, improved stability, methods of preparing said novel glycopeptides, and methods to use said novel glycopeptides.