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cyclopropylmethyl-formylamino-malonic acid diethyl ester N-acetyl-3-cyclopropylalanine cyclopropylmethyl iodide 2-amino-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-N-methylacetamide (R)-2-((tert-butoxycarbonyl)amino)-3-cyclopropylpropanoic acid (S)-3-Cyclopropyl-2-[((2S,6R)-2,6-dimethyl-piperidine-1-carbonyl)-amino]-propionic acid benzyl ester 2-(S)-hydroxy-3-(cyclopropyl)propanoic acid 海关参考信息
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专利信息
专利号:US-2023364251-A1
优先权日:2020-08-06
标 题:Methods for the synthesis of protein-drug conjugates
发明人:BORCHARDT ALLEN; HUGHES ROBERT MICHAEL
权利人:CIDARA THERAPEUTICS INC
摘要:The present invention relates to intermediates and methods for synthesizing protein-drug conjugates that can be used for the treatment of diseases and related conditions.
专利号:WO-2008138621-A2
优先权日:2007-05-16
标题:Synthesis of aminocyclopentane carboxylic acids
专利号:US-9549972-B2
优先权日:2010-08-18
标 题 :MHC-I restricted epitopes containing non-natural amino acid residues
发明人:KYLE DONALD J; SOLTIS DANIEL A; TUSSEY LYNDA G
权利人:PURDUE PHARMA LP
摘要:The invention provides for the synthesis of more effective generators of a T-cell immune response by providing peptide derivatives that are MHC class I-restricted antigens. The peptide derivatives of the present invention are prepared or derived from a parent peptide of 8 to 11 amino acid residues in length, wherein the peptide derivative contains a non-natural amino acid substituted in place of a naturally-occurring amino acid residue at one or more primary anchor positions in the parent peptide or at position 6, position 7, or the C-terminus.
专利号:EP-4192512-A1
优先权日:2020-08-06
标题 :Methods for the synthesis of protein-drug conjugates
专利号:US-7091360-B2
优先权日:2002-04-16
标 题:Process for preparing heteroaryl and unsaturated heterocycloalkylmagnesium reagents and uses thereof
发明人:LI JIAYAO; LINK JOHN O; COLLADANT COLETTE
权利人:AVENTIS PHARMA SA
摘要:The present invention is directed to a novel process for preparing heteroaryl and unsaturated heterocycloalkylmagnesium reagents that are useful in the synthesis of a variety of pharmaceuticals, in particular certain cysteine protease inhibitors.
专利号:EP-1992610-A1
优先权日:2007-05-16
标题:New route of synthesis