CAS: 15785-52-1; 2-Amino-3-Cyclopropylpropanoic Acid

该化合物是一种非蛋白性氨基酸,具有环丙基侧链,具有独特的结构和反应特性,该化合物因其受限环状系统,对药用化学和酸研究具有兴趣,因为这种系统能够加强相容稳定性和影响生物活动,其环丙基化合物组也具有选择性功能化的潜力,使其成为合成应用中有价值的中间体.该化合物的手部中心允许进行对应选择性合成,从而能够研究药物设计中的立体化学影响,其在生理条件下的稳定进一步支持其在生物化学和药理学研究中的效用.

结构式图片

相似化合物

102735-53-5 121786-39-8 214750-76-2

上下游产品

cyclopropylmethyl-formylamino-malonic acid diethyl ester N-acetyl-3-cyclopropylalanine cyclopropylmethyl iodide 2-amino-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-N-methylacetamide (R)-2-((tert-butoxycarbonyl)amino)-3-cyclopropylpropanoic acid (S)-3-Cyclopropyl-2-[((2S,6R)-2,6-dimethyl-piperidine-1-carbonyl)-amino]-propionic acid benzyl ester 2-(S)-hydroxy-3-(cyclopropyl)propanoic acid

合成工艺路线路线简述

    海关参考信息

    专利信息


    专利号:US-2023364251-A1
    优先权日:2020-08-06
    标 题:Methods for the synthesis of protein-drug conjugates
    发明人:BORCHARDT ALLEN; HUGHES ROBERT MICHAEL
    权利人:CIDARA THERAPEUTICS INC
    摘要:The present invention relates to intermediates and methods for synthesizing protein-drug conjugates that can be used for the treatment of diseases and related conditions.

    专利号:WO-2008138621-A2
    优先权日:2007-05-16
    标题:Synthesis of aminocyclopentane carboxylic acids

    专利号:US-9549972-B2
    优先权日:2010-08-18
    标 题 :MHC-I restricted epitopes containing non-natural amino acid residues
    发明人:KYLE DONALD J; SOLTIS DANIEL A; TUSSEY LYNDA G
    权利人:PURDUE PHARMA LP
    摘要:The invention provides for the synthesis of more effective generators of a T-cell immune response by providing peptide derivatives that are MHC class I-restricted antigens. The peptide derivatives of the present invention are prepared or derived from a parent peptide of 8 to 11 amino acid residues in length, wherein the peptide derivative contains a non-natural amino acid substituted in place of a naturally-occurring amino acid residue at one or more primary anchor positions in the parent peptide or at position 6, position 7, or the C-terminus.

    专利号:EP-4192512-A1
    优先权日:2020-08-06
    标题 :Methods for the synthesis of protein-drug conjugates

    专利号:US-7091360-B2
    优先权日:2002-04-16
    标 题:Process for preparing heteroaryl and unsaturated heterocycloalkylmagnesium reagents and uses thereof
    发明人:LI JIAYAO; LINK JOHN O; COLLADANT COLETTE
    权利人:AVENTIS PHARMA SA
    摘要:The present invention is directed to a novel process for preparing heteroaryl and unsaturated heterocycloalkylmagnesium reagents that are useful in the synthesis of a variety of pharmaceuticals, in particular certain cysteine protease inhibitors.

    专利号:EP-1992610-A1
    优先权日:2007-05-16
    标题:New route of synthesis

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1023/a:1017986108720
    摘要:Drehmel DC, Chilton WS. Characterization and Toxicity of Amanita cokeri Extract. Journal of Chemical Ecology. 2002 Feb;28(2):333–41. doi: 10.1023/a:1017986108720.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知