CAS: 137-17-7; 2,4,5-Trimethylaniline

该化合物是一种芳香的芳香矿,其分子式为C9H13N,其特征为三个甲基组,替代在葵线环的2,4和5位置上,该化合物通常用作有机合成的中间体,特别是在染料,颜料和农用化学物的生产中,其结构特征增强了电益替代反应的回活性和选择性,使其对精细化学应用很有价值.该化合物在有机溶剂中表现出中等溶性,由于其潜在毒性需要谨慎处理.该化合物在受控条件下的一贯纯度和稳定性确保了工业和研究环境中的可靠性能.建议适当的储存和安全措施以保持其完整性.

结构式图片

相似化合物

610-91-3 767-77-1 1467-35-2

欧盟法规

统一分类与标签压力设备指令-第1组危险流体ECHA物质ECHA物质工作场所安全标识要求化妆品禁用物质清单C&L通报食品接触材料-禁用CMR物质REACH预注册废弃物危险特性清单

上下游产品

CAS号610-91-3 5-硝-1,2,4-三甲苯 | CAS号95-63-6 1,2,4-三甲苯 | CAS号121-72-2 N,N-二甲基间甲苯胺 | CAS号67-56-1 甲醇 | CAS号638-03-9 间甲苯胺盐酸盐 | CAS号7356-54-9 3,4-二甲基苯胺盐酸盐 | CAS号5435-44-9 N-(1-ethoxycarb... | CAS号7647-01-0 盐酸 | CAS号95-78-3 2,5-二甲基苯胺 | CAS号50-00-0 甲醛 | CAS号496-78-6 2,4,5-三甲基苯酚 | CAS号5469-19-2 5-溴-1,2,4-三甲基苯 | CAS号2234-75-5 1,2,4-三甲基环己烷 | CAS号95-63-6 1,2,4-三甲苯 | CAS号58260-83-6 2,4,5-三甲基苯甲腈 | CAS号610-91-3 5-硝-1,2,4-三甲苯 | CAS号528-90-5 2,4,5-三甲基苯甲酸 | CAS号15460-08-9 2-bromo-3,4,6-t... | CAS号158815-55-5 1,2,4-trimethyl... | CAS号117174-87-5 1-(2,4,5-三甲基苯基)-2-硫脲

合成工艺路线路线简述

    1,2,4-三甲基苯置于palladium On Activated Charcoal 盐酸,硫酸,氢气,硝酸体系中,25.0 °C,3.04 Mpa 条件下,反应生成2,4,5-三甲基苯胺
    参考文献:合成von Plectranthonen,Diterpenoiden Phenanthren-1,4-Chinonen
    标题:合成von Plectranthonen,Diterpenoiden Phenanthren-1,4-Chinonen
    摘要:Lect香,双萜菲-1,4-二酮的合成
    Doi:10.1002/hlca.19900730105

    海关参考信息

    专利信息


    专利号:WO-2011106986-A1
    优先权日:2010-03-02
    标题:Inhibitors of hepatitis c virus ns5b polymerase
    发明人:MCCOMAS CASEY CAMERON; LIVERTON NIGEL J; SOLL RICHARD; LI PENG; PENG XUANJIA; WU HAO
    权利人:MERCK SHARP & DOHME; MCCOMAS CASEY CAMERON; LIVERTON NIGEL J; SOLL RICHARD; LI PENG; PENG XUANJIA; WU HAO
    摘要:Compounds of formula (I) that are used as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and /or viral production in a cell-based system. Wherein Z, R 30 , R 40 , R 50 and R 60 of compounds of formula (I) are herein defined as in the description.

    专利号:US-12071388-B2
    优先权日:2020-12-24
    标 题:Full continuous flow synthesis process of fluorine-containing aromatic hydrocarbon compounds
    发明人:YUAN QILIANG; MIAO YONGYI; SHI YONGGEN; ZHANG YIQIANG; CHEN YINHAO; WANG CHAO
    权利人:FUJIAN ZHONGXIN FLUORIDE MATERIAL GAOBAO TECH CO LTD; ZHEJIANG ZHONGXIN FLUORIDE MAT CO LTD
    摘要:A full continuous flow synthesis process of fluorine-containing aromatic hydrocarbon compounds. Aromatic amine and hydrogen fluoride are respectively pumped into thermostats A and B, then flow into micro-channel reactor C for salt forming reaction whose temperature is kept constant; sulfuric acid solution of nitrosylsulfuric acid is pumped into thermostat D; after keeping the temperature constant, the sulfuric acid solution of nitrosylsulfuric acid and salt forming product flowing out from the micro-channel reactor C flow into micro-channel reactor E for diazotization reaction; the obtained product flows into micro-channel reactor F for thermal decomposition reaction, is cooled in cooler G, then enters three-phase separator H for continuous separation, fluorine-containing aromatic hydrocarbon crude product is subjected to continuous alkaline washing, drying and rectification to obtain fluorine-containing aromatic hydrocarbon finished product, and mixture of hydrofluoric acid and sulfuric acid is continuously distilled to obtain hydrogen fluoride and sulfuric acid.

    专利号:WO-2009143405-A2
    优先权日:2008-05-22
    标 题:Synthesis of graphene sheets and nanoparticle composites comprising same

    专利号:US-2011186789-A1
    优先权日:2008-05-22
    标题:Synthesis of graphene sheets and nanoparticle composites comprising same
    发明人:SAMULSKI EDWARD T; SI YONGCHAO; DINGEMANS THEO
    权利人:UNIV NORTH CAROLINA
    摘要:A method for producing isolatable and dispersible graphene sheets, wherein the graphene sheets may be tailored to be soluble in aqueous, non-aqueous or semi-aqueous solutions. The water soluble graphene sheets may be used to produce a metal nanoparticle-graphene composite having a specific surface area that is 20 times greater than aggregated graphene sheets. Graphene sheets that are soluble in organic solvents may be used to make graphene-polymer composites.

    专利号:CN-112608212-A
    优先权日:2020-12-24
    标题 :A kind of fully continuous flow synthesis process of fluorine-containing aromatic compounds

    专利号:US-2022204427-A1
    优先权日:2020-12-24
    标 题:Full continuous flow synthesis process of fluorine-containing aromatic hydrocarbon compounds
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    合成参考文献


    摘要:Mortelmans K et al; Environ Mutagen 8:1-119 (1986)
    摘要:Franke C et al; Chemosphere 29: 1501-14 (1994)
    摘要:WEISBURGER EK ET AL; J ENVIRON PATHOL TOXICOL 2(2) 325-356 (1978)
    摘要:Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 13th ed. New York, NY: John Wiley & Sons, Inc. 1997., p. 938
    摘要:USEPA; EMMI. EPA's Environmental Monitoring Methods Index. Version 1.1. PC# 4082. Rockville, MD: Government Institutes (1997)
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