CAS: 1260-17-9; 3,5,6,8-Tetrahydroxy-1-Methyl-9,10-Dioxo-7-((2S,3R,4R,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)-9,10-Dihydroanthracene-2-Carboxylic Acid

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CAS号76173-05-2 4-chloro-N-meth... | CAS号137410-42-5 3,5,8-trihydrox... | CAS号485-47-2 茚三酮

📜葡萄糖置于engineered Escherichia Coli Strain Bap1 Harboring Antdefbg (Encoding Type Ii Polyketide Synthase From Photorhabdus Luminescens),Zhuij (Encoding Cyclases From Streptomyces Sp. R1128),Dnrf[p217K] (Encoding Aklavinone 12-Hydroxylase[p217K] From Streptomyces Peucetius),And Gtcgt[v93Q/y193F] (Encoding Udp-Glucosyltransferase[v93Q/y193F] From Gentiana Triflora),With Overexpression Of Corynebacterium Glutamicum Accbcd1体系中,用 Aq. Phosphate Buffer 用作溶剂,化学反应生成胭脂红酸
参考文献:代谢工程大肠杆菌生产胭脂红酸
标题:代谢工程大肠杆菌生产胭脂红酸
摘要:胭脂红酸是一种在介壳虫(即指藻)中发现的芳香族聚酮化合物,是一种广泛使用的天然红色着色剂.长期以来,它是通过繁琐的昆虫养殖和多步纯化过程生产的.因此,人们对通过工程细菌发酵生产胭脂红酸产生了很大的兴趣.在这里,我们报道了工程大肠杆菌中葡萄糖完全生物合成胭脂红酸的过程.我们首先优化了发光杆菌 ( Photorhabdus Luminescens ) 的 Ii 型聚酮合酶机制,通过链霉菌(Streptomyces Sp) 环化酶 Zhui 和 Zhuj 的共表达,能够高水平生产黄酮酮酸. R1128.为了发现负责其余两个反应(羟基化和c-葡萄糖基化)的酶,通过测试报告执行类似反应的候选酶来进行生化反应分析.两种鉴定的酶,来自链霉菌的aklavinone 12-羟化酶(dnrf)和来自三花龙胆的c-葡萄糖基转移酶(gtcgt),分别可以成功地进行黄酮酸的羟基化和c-葡萄糖基化.然后,进行同源建模
Doi:10.1021/jacs.0C12406

专利信息

专利号:US-5424421-A
优先权日:1990-07-17
标 题:Synthesis of carminic acid and principal intermediates
发明人：TYMAN JOHN H P; FIECCHI ALBERTO
权利人:EUROP COLOUR PLC
摘要:The invention relates to the synthesis of 6-deoxykermesates, 6-deoxykermesic acid, and carminic acid, based on a reaction of a 2-halogenonapthazarin with a bis-trimethylsilyl-diene.

专利号:US-2023097824-A1
优先权日:2020-05-08
标 题:Semi-synthesis and use of racemic hematoxylin
发明人：DURRANT EDWARD E; HEINDL DIETER; HUBER FLORIAN MAURITIUS ERASUMU; KLEIN ERIC; KOSMEDER II JEROME W; VOSS EDGAR
权利人:VENTANA MED SYST INC; ROCHE DIAGNOSTICS OPERATIONS INC
摘要:A racemic hematoxylin formulation is disclosed that includes one or both of a stabilizer compound and an antioxidant. The disclosed composition exhibits sufficient stability to be utilized in an automated staining process. Methods of using and making the stabilized composition also are disclosed.

专利号:US-10772990-B2
优先权日:2014-04-01
标题 :Tissue filler compositions and methods of use
发明人：NIKOLIS ANDREAS; HERBERT LISE
权利人:KLOX TECH INC
摘要:The present disclosure relates to methods for stimulating collagen synthesis, cosmetic enhancement of soft tissue and/or inhibiting or treating scarring comprising administering a composition to an area to be treated within a soft tissue, wherein the composition comprises a tissue filler medium and a fluorophore; and illuminating the area with light having a wavelength which can be absorbed by the fluorophore.

专利号:US-8012220-B2
优先权日:2006-04-13
标题 :Specific monocationic monochromophoric compounds of hydrazone type comprising a 2-, 4-pyridinium or 2-, 4-quinolinium unit, synthesis thereof, dye compositions containing them, and method for dyeing keratin fibres
发明人：DAVID HERVE; MURGUET NADEGE; GREAVES ANDREW
权利人:OREAL
摘要:The present disclosure relates to monocationic monochromophoric compounds of formula (I) and (II) and dyeing compositions and multicompartment devices comprising monocationic monochromophoric compounds of formula (I) and (II). The disclosure also relates to methods for preparing monocationic monochromophoric compounds of formula (I) and (II), and also to methods for dyeing comprising applying monocationic monochromophoric compounds of formula (I) and (II) to keratin fibers.

专利号:US-2003186237-A1
优先权日:2001-02-14
标题:Methods and compositions of amplifying RNA
发明人：GINSBERG STEPHEN D; CHE SHAOLI
权利人:BAYLOR COLLEGE MEDICINE
摘要:The present invention pertains to a method that will increase the efficiency of second strand cDNA synthesis through a mechanism of “terminal continuationâ€? before further RNA amplification by RNA transcription using, for example, a bacteriophage promoter. In a specific embodiment, a transcription promoter is attached to the 5′ region of cDNA through the same mechanism of “terminal continuationâ€?. Genetic signals are subsequently amplified in a linear manner through RNA transcription. In specific embodiments, the orientation of the transcribed RNA is either sense or antisense, depending on the desired downstream application. In other embodiments, the present invention pertains to methods for extraction and amplification of RNA, particularly mRNA, from histologically stained tissues and cells.

专利号:GB-2332428-A
优先权日:1997-12-12
标题:Synthesis of 1-methyl-7-(1rs,2r,3s,4s,5s)-2,3,4,5,6-pentabenzyloxy-1-hydroxyhexyl-3,5,8-trihydroxyanthra-9,10-quinone-2-carboxylic acid and intermediates