CAS: 1070-83-3; 3,3-Dimethylbutyric Acid

相似化合物

2987-16-8 624-95-3 5340-78-3

上下游产品

CAS号2987-16-8 3,3-二甲基丁醛 | CAS号624-95-3 3,3-二甲基-1-丁醇 | CAS号75-35-4 1,1-二氯乙烯 | CAS号75-65-0 叔丁醇 | CAS号590-50-1 4,4-二甲基-2-戊酮 | CAS号140614-17-1 tBuCH2CH2B(OH)2 | CAS号507-20-0 氯代叔丁烷 | CAS号7732-18-5 水 | CAS号815-17-8 三甲基丙酮酸 | CAS号5340-78-3 叔丁基乙酸乙酯 | CAS号33509-43-2 4-氨基-6-(叔丁基)-3-... | CAS号21862-63-5 反-4-叔丁基环己醇 | CAS号937-05-3 顺-4-叔丁基环己醇 | CAS号85136-35-2 4-(tert-butyl)c... | CAS号19910-29-3 2,3,3-三甲基丁酸 | CAS号20201-39-2 2-溴-3,3-二甲基丁酸乙酯 | CAS号190260-61-8 2-bromo-3,3-dim... | CAS号19910-30-6 Butanoic acid, ... | CAS号29846-86-4 N,N-dibutyl-3,3...

Neo-Hexylboronic Acid置于chromium(Vi) Oxide体系中,用 二氯甲烷,溶剂黄146 用作溶剂,化学反应 12.0H,以80%的收率获得3,3-二甲基-1-丁酸
参考文献:A Convenient Procedure For The Direct Conversion Of Terminal Alkenes Into Carboxylic Acids
标题:A Convenient Procedure For The Direct Conversion Of Terminal Alkenes Into Carboxylic Acids
摘要:Alkylboronic Acids,Readily Synthesized From A Variety Of Representative Terminal Alkenes Via Hydroboration With Dibromoborane-Methyl Sulfide,Undergo A Facile Oxidation With Chromium Trioxide In 90% Aqueous Acetic Acid To Provide Carboxylic Acids In 80-97% Isolated Yields,Without Rearrangement Or Loss Of Carbon.
Doi:10.1016/s0040-4039(00)91853-7

专利信息

专利号:US-11667658-B2
优先权日:2021-06-30
标 题:Chemical synthesis of the organoarsenical antibiotic arsinothricin
发明人：ROSEN BARRY P; YOSHINAGA MASAFUMI; WNUK STANISLAW F; HOWLADER MD ABU HASAN; SUZOL SK MD SAZZAD HOSSAIN
权利人:ROSEN BARRY P; YOSHINAGA MASAFUMI; WNUK STANISLAW F; HOWLADER MD ABU HASAN; SUZOL SK MD SAZZAD HOSSAIN; THE FLORIDA INTERNATIONAL UNIV BOARD OF TRUSTEES
摘要:The subject invention provides methods for the chemical synthesis of racemic arsinothricin (D,L-AST), the novel organoarsenical antibiotic. One is by condensation of the 2-chloroethyl(methyl)arsinic acid with acetamidomalonate, and the second involves reduction of the N-acetyl-protected derivative of hydroxyarsinothricin (AST-OH) and subsequent methylation of the resulting sodium salt of trivalent arsenic intermediate with methyl iodide. The enzyme AST N-acetyltransferase (ArsN1) was utilized to purify L-AST from racemic AST. This expedient chemical synthesis of AST provides a source of this novel antibiotic for future drug development.

专利号:US-2022298204-A1
优先权日:2019-07-05
标题 :Synthesis of a-amanitin and its derivatives
发明人：SIEGERT MARY-ANN; KNITTEL CAROLINE HERTA; SÃœSSMUTH RODERICH
权利人:PURE BIOORGANICS SIA
摘要:The present invention relates to the chemical synthesis of α-amanitin and its derivatives. The present invention also relates to intermediate products of the α-amanitin synthesis.

专利号:US-11639349-B2
优先权日:2020-05-28
标题:Stereoselective synthesis of intermediate for preparation of heterocyclic compound
发明人：CHEN WEN-CHANG; HSU HAN-PEI; CHOU SHAN-YEN; CHUANG SHIH-CHIEH; YEN CHI-FENG
权利人:TAI GEN BIOTECHNOLOGY CO LTD; TAIGEN BIOPHARMACEUTICALS CO BEIJING LTD; TAIGEN BIOTECHNOLOGY CO LTD
摘要:Provided is a stereoselective synthesis of an intermediate for the preparation of the heterocyclic derivative as a Cap-dependent endonuclease inhibitor. The synthesis process has the advantages of simple operation, higher yield and relatively controllable steroselectivity, such that it is suitable for large-scale production.

专利号:US-6815214-B2
优先权日:2000-12-29
标 题 :Pharmaceutical uses and synthesis of diketopiperazines
发明人：BOYCE JIM P; HOWBERT J JEFFRY; TABONE JOHN C
权利人:CELLTECH R & D INC
摘要:The synthesis of novel diketopiperazines, their use in inhibiting cellular events such as those involving NFK-α, NFK-β and in the treatment of inflammation events, a combinatorial library of diverse diketopiperazines and process for their synthesis as a library and as individual compounds. In particular novel diketopiperazines are disclosed including their synthesis and use in cellular events such as activation of the transcription factor, nuclear factor, TNF-α, TNF-β and also apoptosis.

专利号:US-9957355-B2
优先权日:2013-06-12
标 题 :Device and method for synthesis of a polymer under separation of a gaseous substance
发明人：ZHU NING; STAMMER ACHIM; CLAUSS JOACHIM; KORY GAD
权利人:BASF SE
摘要:The invention relates to a device for synthesis of a polymer under separation of a gaseous substance. Said device comprises a reaction chamber ( 1 ), which has a top section ( 11 ), a middle section ( 12 ) and a bottom section ( 13 ), an inlet opening ( 2 ) which is arranged in the middle section ( 12 ), a first outlet opening ( 3 ) which is arranged in the bottom section ( 13 ), a second outlet opening ( 4 ) which is arranged in the top section ( 11 ), a first return opening ( 51 ), which is arranged in the bottom section ( 13 ), a second outlet opening ( 52 ), which is arranged under the top section ( 11 ), a distribution device ( 6 ), which is arranged between the top section ( 11 ) and the middle section ( 12 ), and a removal device ( 7 ) which is arranged to be movable along the top section ( 11 ). The invention further relates to a method for synthesis of a polymer which can be carried out in said device.

专利号:US-7138526-B1
优先权日:1999-06-15
标 题 :Solid phase synthesis of n,n-disubstituted diazacycloalkylcarboxy derivatives
发明人：HERPIN TIMOTHY F; MORTON GEORGE C; SALVINO JOSEPH M
权利人:AVENTIS PHARMA INC
摘要:A method for the solid phase synthesis of N,N-disubstituted diazacycloalkylcarboxy derivatives of general formula (I) and (II) is claimed. Examples include piperazine-2-carboxamide. The method is applicable to the synthesis or large combinatorial libraries