CAS: 10387-13-0; 9,10-Bis(Chloromethyl)Anthracene

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CAS号50-00-0 甲醛 | CAS号120-12-7 蒽 | CAS号7647-01-0 盐酸 | CAS号64-19-7 冰醋酸 | CAS号108365-87-3 N,N'-Bis(2-(dim... | CAS号307554-62-7 9,10-蒽二基-二(亚甲基)二丙二酸 | CAS号19926-08-0 2-[[10-[[bis(2-... | CAS号781-43-1 9,10-二甲基蒽 | CAS号34373-96-1 9,10-双(溴甲基)蒽 | CAS号60974-92-7 9,10-双(二乙基膦甲基)蒽 | CAS号7044-91-9 蒽-9,10-二甲醛 | CAS号10273-85-5 9,10-二(羟甲基)蒽 | CAS号10273-84-4 蒽-9,10-二基双(亚甲基) 二乙酸酯 | CAS号13417-34-0 9,10-dimethyl-9...

📜聚合甲醛,蒽置于盐酸体系中,用 1,4-二氧六环,水 用作溶剂,化学反应 5.0H,以38%的收率获得9,10-二(氯甲基)蒽
参考文献:杂原子辅助聚集诱导的增强发射(aiee)化合物的溶剂变色,可逆色差和自组装效应
标题:杂原子辅助聚集诱导的增强发射(aiee)化合物的溶剂变色,可逆色差和自组装效应
摘要:合成并研究了两种化合物,9,10-双[2-(喹啉基)乙烯基]蒽(bqva)和9,10-双[2-(萘-2-基)乙烯基]蒽(bnva).它们都具有聚集诱导的增强发射(aiee)特性.杂原子辅助的bqva表现出溶剂变色,可逆的变色性质和自组装效应.当增加溶剂极性时,Bqva的绿色溶液变为橙色,荧光发射波长从λ = 527到565 Nm发生红移.值得注意的是,Bqva具有可逆的色差特性,包括机械色差和热色差.所制备的粉末bqva显示绿色荧光(λ Em = 525纳米)和颜色可以变成橙(λ Em= 573Nm).有趣的是,橙色可以在高温下返回.基于这些可逆的色度特性,设计了一种简单方便的可擦除板.与bqva不同,非杂原子辅助的bnva没有清晰的发色过程.X射线衍射,差示扫描量热法,单晶分析和理论计算得出的结果表明,铬化过程取决于bqva中的杂原子.此外,Bqva在不同溶剂中也表现出出色的自组装效果.
Doi:10.1002/chem.201501902

专利信息

专利号:US-10597342-B2
优先权日:2017-03-29
标 题 :Method for the synthesis of 9,10-bis(chloromethyl)anthracene
发明人：ORTEGA HIGUERUELO FRANCISCO JOSÉ; LANGA DE LA PUENTE FERNANDO
权利人:UNIV CASTILLA LA MANCHA
摘要:The invention relates to a method for the synthesis of 9,10-bis(chloromethyl) anthracene, comprising the mixing of the reagents, anthracene and 1,3,5-trioxane, a phase transfer catalyst selected from the group comprising quarternary ammonium salt and crown ether with hydrochloric acid and acetic acid.

专利号:US-7189864-B2
优先权日:1990-11-19
标 题:Method of preparing intermediates useful in synthesis of retroviral protease inhibitors
发明人：NG JOHN S; PRZYBYLA CLAIRE A; MUELLER RICHARD A; VAZQUEZ MICHAEL L; GETMAN DANIEL P
权利人:SEARLE & CO
摘要:A synthesis is described for intermediates which are readily amenable to the large scale preparation of hydroxyethylurea-based chiral HIV protease inhibitors. The method includes forming a diastereoselective epoxide from a chiral alpha amino aldehyde.

专利号:US-6022996-A
优先权日:1990-11-19
标 题 :Method for making intermediates useful in synthesis of retroviral protease inhibitors
发明人：NG JOHN S; PRZYBYLA CLAIRE A; MUELLER RICHARD A; VAZQUEZ MICHAEL L; GETMAN DANIEL P
权利人:SEARLE & CO
摘要:A synthesis is described for intermediates which are readily amenable to the large scale preparation of hydroxyethylurea-based chiral HIV protease inhibitors. The method includes forming a diastereoselective epoxide from a chiral alpha amino aldehyde.

专利号:EP-0641333-B1
优先权日:1992-05-20
标 题 :Method for making intermediates useful in synthesis of retroviral protease inhibitors
发明人：NG JOHN S; PRZYBYLA CLAIRE A; MUELLER RICHARD A; VAZQUEZ MICHAEL L; GETMAN DANIEL P
权利人:SEARLE & CO; MONSANTO CO
摘要:A synthesis is described for intermediates which are readily amenable to the large scale preparation of hydroxyethylurea-based chiral HIV protease inhibitors. The method includes forming a diastereoselective epoxide compound of formula (I) from a chiral alpha amino aldehyde and halomethyllithium as an organometallic methylene-adding reagent. In formula (I) R<1> is selected from alkyl, aryl, cycloalkyl, cycloalkylalkyl and arylalkyl, which are optionally substituted with a group selected from alkyl, halogen, NO2, OR<9> or SR<9>, where R<9> represents hydrogen or alkyl; and P<1> and P<2> independently are selected from amine protecting groups, including but not limited to, arylalkyl, substituted arylalkyl, cycloalkenylalkyl and substituted cycloalkenylalkyl, allyl, substituted allyl, acyl, alkoxycarbonyl, aralkoxycarbonyl and silyl.

专利号:EP-0855388-B1
优先权日:1993-11-23
标 题 :Method for making intermediates useful in synthesis of retroviral protease inhibitors
发明人：NG JOHN S; PRZYBYLA CLAIRE A; MUELLER RICHARD A; VAZQUEZ MICHAEL L; GETMAN DANIEL P; FRESKOS JOHN J; DECRESCENZO GARY A; BERTENSHAW DEBORAH E; HEINTZ ROBERT M; ZHANG SUHONG; LIU CHIN; LANEMAN SCOTT A
权利人:SEARLE & CO
摘要:A synthesis is described for intermediates which are readily amenable to the large scale preparation of hydroxyethylurea-based chiral HIV protease inhibitors. The method includes forming a cyanohydrin from a chiral alpha amino aldehyde.

专利号:US-2002161234-A1
优先权日:1990-11-19
标 题 :Method of preparing intermediates useful in synthesis of retroviral protease inhibitors