CAS: 557-61-9; Octacosan-1-Ol

上下游产品

ethyl °Ctacosanoate methyl °Ctacosanoate sodium °Ctacosanoate °Ctacos-9-yn-1-ol °Ctacosanoic acid °Ctacosanol acetate 1-bromo-°Ctacosane °Ctacosanal aldehyde

14-[tert-Butyl(Diphenyl)Silyl]Oxytetradecanal置于palladium 10% On Activated Carbon,四丁基氟化铵,氢气,Sodium Hexamethyldisilazane体系中,用 四氢呋喃,乙酸乙酯 作为反应溶剂,化学反应生成 二十八烷醇
参考文献:Synthesis Of Long-Chain Fatty Acid Derivatives As A Novel Anti-Alzheimer's Agent
标题:Synthesis Of Long-Chain Fatty Acid Derivatives As A Novel Anti-Alzheimer's Agent
摘要:In Order To Develop New Drugs For Alzheimer'S Disease,We Prepared 17 Fatty Acid Derivatives With Different Chain Lengths And Different Numbers And Positions Of Double Bonds By Using Wittig Reaction And Stereospecific Hydrogenation Of Triple Bonds As Key Reactions. Among Them,(4Z,15Z)-octadecadienoic Acid (10) And (23Z,34Z)-Heptatriacontadienoic Acid (16) Showed The Most Potent Neurite Outgrowth Activities On A Beta(25-35)-Treated Rat Cortical Neurons,Which Activities Were Comparable To That Of A Positive Control,Ngf. Both Fatty Acids 10 And 16 Possess Two (Z)-Double Bonds At The N-3 And N-14 Positions,Which Might Be Important For The Neurite Outgrowth Activity. (C) 2013 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Bmcl.2013.12.008

专利信息

专利号:US-2022305176-A1
优先权日:2019-08-30
标题 :Biodegradable soft elastomers for regenerative engineering
发明人：AMEER GUILLERMO A; SHARMA ARUN K; WANG XINLONG; BURY MATTHEW I
权利人:UNIV NORTHWESTERN; ANN AND ROBERT H LURIE CHILDRENS HOSPITAL OF CHICAGO
摘要:Provided herein are materials and methods related to scaffolds and uses thereof. In some embodiments, provided herein are poly (octamethylene-octanol citrates) (POOC) scaffolds with native mechanical properties that are comparable to urinary bladder tissue. In some embodiments, provided herein are methods for the synthesis of POOC scaffolds with native mechanical properties that are comparable to urinary bladder tissue by including octanol in the polycondensation synthesis of POC. In some embodiments, provided herein are methods of use of the disclosed scaffolds, including for urinary bladder tissue regeneration.

专利号:US-8067465-B2
优先权日:2002-01-15
标题:Tricyclic-bis-enone derivatives and methods of use thereof
发明人：HONDA TADASHI; FAVALORO FRANK G; GRIBBLE GORDON W; SPORN MICHAEL B; SUH NANJOO
权利人:HONDA TADASHI; FAVALORO FRANK G; GRIBBLE GORDON W; SPORN MICHAEL B; SUH NANJOO; DARTMOUTH COLLEGE
摘要:Novel tricyclic-bis-enone derivatives (TBEs) as well as the process for the preparation of such TBEs are provided. Also provided are methods for prevention and/or treatment of cancer, Alzheimer's disease, Parkinson's disease, multiple sclerosis, amyotropic lateral sclerosis, rheumatoid arthritis, inflammatory bowel disease, and all other diseases whose pathogenesis is believed to involve excessive production of either nitric oxide (NO) or prostaglandins or the overexpression of iNOS or COX-2 genes or gene products. Further, methods for the synthesis of the TBE compounds of the invention utilize cheap commercially available reagents and are highly cost effective and amenable to scale-up. Additional high efficiency synthetic methods that utilize novel intermediates as well as the synthesis of these intermediates are also provided. Furthermore, the invention also provides methods for designing novel and water-soluble TBEs.

专利号:US-4367346-A
优先权日:1981-04-23
标 题 :Method for synthesis of long-chain alcohols
发明人：PARKER DANE K
权利人:GOODYEAR TIRE & RUBBER
摘要:This invention is concerned with the preparation of long-chain carboxylic acids and alcohols from cyclododecanone and acyl chlorides. More specifically, this invention relates to a process for the preparation of 1-triacontanol, CH 3 (CH 2 ) 28 CH 2 OH. Triacontanol acts as a growth stimulant on a wide range of plants to increase dry weight gains, water uptake, water use efficiency and protein synthesis in treated plants.

专利号:US-9068192-B2
优先权日:2009-01-28
标 题:Compositions and methods for conversion of aldehydes to alkanes
发明人：ZENG WEIQING; HE SHENG YANG
权利人:ZENG WEIQING; HE SHENG YANG; UNIV MICHIGAN STATE
摘要:The invention provides the discovery that SCD2 (Susceptible to Coronatine-Deficient Pst DC3118-2) protein converts aldehydes to alkanes, thereby changing the composition and/or amount of synthesized waxes. The invention additionally provides homologs, orthologs and paralogs of SCD2 protein, and nucleotide sequences encoding these proteins. Also provided are expression vectors, transgenic cells, transgenic plants, transgenic seeds, methods for altering alkane production in cells, methods for identifying the function of a nucleotide sequence in the synthesis of plant surface wax, and methods for identifying plant tissue that has an altered surface wax composition. The invention's compositions and methods are useful for altering the amount and/or composition of wax produced by cells, including plants and seeds, that have been transformed with the invention's sequences.

专利号:US-8329854-B2
优先权日:2010-09-27
标题 :Synthesis of tri-component resins
发明人：BIRAU MARIA; ALLEN C GEOFFREY
权利人:BIRAU MARIA; ALLEN C GEOFFREY; XEROX CORP
摘要:A resinous compound of the formulas or a salt thereof, wherein G1 is —X1C(O)OR1, —X2OC(O)R2, or —X2OH; G2 is R4, R12, —C(O)R2, —C(O)X1C(O)OR1, or —C(O)X2OC(O)R2; R1 is an alkyl having from 10 to 80 carbon atoms; R2 is an alkyl having from 2 to 40 carbon atoms; each R3 and R4 is independently hydrogen, alkyl, arylalkyl or alkylaryl; each R5 and each R6 is independently hydrogen or alkyl; X1 and X2 are both a straight or branched alkylene group; t1 is 1 to 20; t2 and t3 is independently 0 to 20; u1 is 1 to 30; u2 and u3 is independently 0 to 30; each R7 and each R8 is independently hydrogen, alkyl, or alkoxyl; each R9 and each R10 is independently hydrogen, alkyl, or alkoxyl; Ar is a substituted or unsubstituted aromatic moiety; p is 1 to 5; q is 1 to 12; A⊖ is selected from the group consisting of Cl−, Br−, I−, HSO4−, HSO3−, CH3SO3−, NO3−, HCOO−, CH3COO−, H2PO4−, SCN−, BF4−, ClO4−, SSO3−, PF6−, and SbCl6−; and J is alkyl, arylalkyl, or alkylaryl.

专利号:US-9365532-B1
优先权日:2011-02-14
标题:Synthesis, composition and use of novel therapeutic and cosmetic Schiff base products formed by reaction of a carbonyl containing moeity with a transimination nucleophilic catalyst and the use of transimination nucleophilic catalysts to increase the rate at which carbonyl containing therapeutic and cosmetic actives form Schiff base products with biological amines
发明人：ISAACMAN STEVEN
权利人:ISAACMAN STEVEN; NANOMETICS LLC
摘要:The present invention relates to the synthesis, composition and use of novel moieties formed by reacting a transimination nucleophilic catalyst, molecular or polymeric, with carbonyl-containing therapeutic or cosmetic moieties. The resultant Schiff base product is highly reactive towards transimination with a biological amine. The catalyst and carbonyl-containing moiety can be molecular or polymeric, and the resultant chemical and physical properties of the Schiff base products can be engineered by appropriate selection of said catalyst. The present invention also relates to the synthesis, composition and use of novel moieties that are used as actives in sunless tanning preparations. The present invention also relates to the use of transimination nucleophilic catalysts to increase the rate at which a carbonyl-containing moiety reacts with a biological amine. The present invention also relates to the use of transimination nucleophilic catalysts to increase the rate and efficacy of commercial sunless tanning preparations. Improvements on stability and efficacy of said preparations are disclosed. While the invention has been described in terms of its preferred embodiments, those skilled in the art will recognize that the invention can be practiced with modification within the spirit and scope of the appended claims. Accordingly, the present invention should not be limited to the embodiments as described above, but should further include all modifications and equivalents thereof within the spirit and scope of the description provided herein.