📜邻溴苯甲醛置于对甲苯磺酸体系中,用 乙二醇,甲苯 用作溶剂,以94%的收率获得2-溴苯甲醛乙烯醛 参考文献:Esters Of (Triarylphosphoranylidene)Carbamic Acid For Effecting Diuresis 标题:Esters Of (Triarylphosphoranylidene)Carbamic Acid For Effecting Diuresis 摘要:这项披露描述了(Triarylphosphoranylidene)Carbamic Acid的新型酯类化合物,这些化合物可作为利尿剂.
专利号:US-8957230-B2 优先权日:2011-06-30 标 题 :Synthesis of cleistanthin A and derivatives thereof 发明人:MULIK NILESH SHRIDHAR; PANGHAVANE KAILASH DATTATRAYA 权利人:MULIK NILESH SHRIDHAR; PANGHAVANE KAILASH DATTATRAYA 摘要:The present invention provides a method for preparing Cleistanthin A, a diphyllin glycoside, derivatives thereof and intermediates thereto. In particular the present invention provides in one of the aspect a method for synthesis of compound of formula D a key intermediate of diphyllin, which can be carried out in a shorter duration and at an ordinary temperature.
专利号:US-9650355-B2 优先权日:2013-01-31 标 题 :Method for preparation of justicidin a derivatives of arylnaphthalene lignan structure 发明人:HAM JUNGYEOB; KIM TAE JUNG; KWON HAK CHEOL; JEONG KYU HYUK; SONG JUNGHO; CHUNG BONG CHUL 权利人:KOREA INST SCI & TECH 摘要:The present disclosure relates to a novel method for preparing an arylnaphthalene lignan compound. In synthesis of arylnaphthalene lignan compounds and derivatives according to the present disclosure, a naphthalene backbone may be constructed first and an aryl group may be introduced at the final stage. Through this, various kinds of derivatives that could not be prepared from the existing methods can be synthesized effectively. Further, the synthesis method according to the present disclosure is appropriate for large-scale production.
专利号:US-10111867-B2 优先权日:2015-02-17 标题:Process and intermediates for the preparation of perampanel 发明人:MAROM EHUD; RUBNOV SHAI 权利人:MAPI PHARMA LTD 摘要:The present invention describes a process for the synthesis of 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-di-hydro-pyridin-2-one (Perampanel) represented by the structure of formula (1), and salts thereof, especially salts with pharmaceutically acceptable acids. The present invention further relates to certain intermediates formed and/or used in such process.
专利号:US-2013012727-A1 优先权日:2011-06-30 标题 :Synthesis of cleistanthin a and derivatives thereof
专利号:RU-2014320-C1 优先权日:1987-09-15 标题:Method of synthesis of propenoic acid derivatives and their stereoisomers
专利号:RU-2024511-C1 优先权日:1986-04-17 标 题 :Method of synthesis of e-isomers of acrylic acid derivatives
参考标题:Vinyl Azides In Heterocyclic Synthesis. Part 6. Synthesis Of Isoquinolines By Intramolecular Aza-Wittig Reaction 作者:Deirdre M. B. Hickey,A. Roderick Mackenzie,Christopher J. Moody,Charles W. Rees 摘要:Azidocinnamates Containing Ortho-Carbonyl Substituents Are Versatile Intermediates For Heterocyclic Synthesis. Isoquinolines (8) And (9) Are Formed Under Mild Neutral Conditions By Intramolecular Aza-Wittig Reactions Of Iminophosphoranes, Readily Derived From Azides (1) And (2), Respectively, With Triethyl Phosphite. The Azafluoranthene (10) Can Also Be Prepared From The Azide (3)Via The Isolable Iminophosphoranes
合成参考文献
摘要:Pilgrim, B. S.; Tucker, M. J., Science of Synthesis Knowledge Updates, (2019) 1, 188. 摘要:Pilgrim, B. S.; Tucker, M. J., Science of Synthesis Knowledge Updates, (2019) 1, 186. 摘要:Pilgrim, B. S.; Tucker, M. J., Science of Synthesis Knowledge Updates, (2019) 1, 184. 摘要:Pilgrim, B. S.; Tucker, M. J., Science of Synthesis Knowledge Updates, (2019) 1, 189.