CAS: 23783-42-8; 2,5,8,11-Tetraoxatridecan-13-Ol

该化合物是一种无色,无味的液体,在水和有机溶剂中可溶解,是甘蓝醚家族的成员,其特点是其醚功能组和长水益乙基甘醇链.TEGME的沸点相对较高,挥发性较低,适合各种应用,包括油漆,涂料和清洁产品的溶剂.其结构允许其作为表面活性剂,增强制剂的湿润和扩散特性.此外,TEGME具有低毒性,被认为是有利的环境特征,因此在安全和环境影响引起关注的制剂中是一种首选选择,还用于生产墨水和粘合剂,以及制药和化妆业.适当的处理和储存对于保持其应用的稳定性和有效性至关重要.

结构式图片

相似化合物

143-24-8 86259-87-2 112-60-7

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

CAS号87117-61-1 2-[2-[2-(2-meth... | CAS号112-60-7 三缩四乙二醇 | CAS号74-88-4 碘甲烷 | CAS号77-78-1 硫酸二甲酯 | CAS号74654-05-0 m-PEG3-OMs | CAS号107-21-1 乙二醇 | CAS号112-35-6 三乙二醇单甲醚 | CAS号86259-87-2 四甘醇单苄醚 | CAS号727986-31-4 2-(2-{2-[2-(2-m... | CAS号73159-12-3 sodium 2,5,8,11... | CAS号104779-02-4 1-[2-[2-[2-[2-(... | CAS号16024-66-1 m-PEG4-CH2COOH | CAS号16024-60-5 m-PEG3-CH2COOH | CAS号1191-91-9 2,5,8,11,14,17,... | CAS号78463-25-9 2-[2-[2-(2-meth... | CAS号85030-56-4 氨基四甘醇单甲醚 | CAS号87117-60-0 1-[2-[2-[2-(2-m... | CAS号848589-21-9 11-[2-[2-[2-(2-... | CAS号89769-11-9 1-[2-[2-(2-etho... | CAS号96220-75-6 Allyloxy(tetrae...

合成工艺路线路线简述

  • 合成目标产物 Tetraethyleneglycol Monomethyl Ether 主要起始原料 2H-Pyran, Tetrahydro-2-(3,6,9,12-Tetraoxatridec-1-Yloxy)-
  • (文献来源)合成步骤主要原料 2H-Pyran, Tetrahydro-2-(3,6,9,12-Tetraoxatridec-1-Yloxy)-
四甘醇单苄醚置于palladium On Activated Charcoal 氢气,Sodium体系中,用 二乙二醇二甲醚,甲苯 用作溶剂,25.0~60.0 °C,455.96 Kpa 条件下,反应 30.0H,反应生成四乙基乙二醇单甲酯
参考文献:单官能(二甲基氨基)硅烷作为硅烷化剂
标题:单官能(二甲基氨基)硅烷作为硅烷化剂
摘要:研究了三有机基(二甲基氨基)硅烷与表面水合二氧化硅的反应.这些甲硅烷基化剂易于由相应的氯硅烷或溴硅烷与二甲胺制备.所得产物是热稳定的和相对挥发性的.在150-250oc下与表面水合二氧化硅制备物反应170 H,得到致密的接枝层.然而,对于具有强极性取代基的(二甲基氨基)硅烷而言,为了获得最大的覆盖率,似乎有必要对表面改性的二氧化硅进行重新处理.
Doi:10.1002/hlca.19840670813

海关参考信息

专利信息


专利号:US-2025236633-A1
优先权日:2022-03-28
标 题:Synthesis of isomerically pure polyol-based phosphoramidites
发明人:BANASIK BRENT; DIAZ CORRAL JULIAN ANDRES; JACOBS AARON; JUD LUKAS; KUCHELMEISTER HANNES; NBAVI MELUD; PFAFFENEDER TONI; SIMONYIOVA SONA; TABONE JOHN C; THUER WILMA
权利人:ROCHE SEQUENCING SOLUTIONS INC
摘要:The present disclosure relates to a process for the regiochemically and enantiomerically controlled synthesis of phosphoramidite-containing monomers, and to intermediate products of this process. In some embodiments, the phosphoramidite-containing monomers or their precursors are regioisomerically and/or enantiomerically pure and may be polymerized into polymers or copolymers.

专利号:US-9273184-B1
优先权日:2009-12-24
标题:Synthesis of highly fluorinated amines for use in polymers and biomaterials
发明人:WILLIAMS TRAVIS J; BOZ EMINE
权利人:WILLIAMS TRAVIS J; BOZ EMINE; UNIV SOUTHERN CALIFORNIA
摘要:A method for forming a fluorinated compound includes a step of forming a sulfonate ester of a polyethylene glycol. The sulfonate ester is then reacted with a fluorinated diol in the presence of a base such that the polyethylene glycol is attached to one of the hydroxyl groups in the fluorinated diol. The other hydroxyl group in the fluorinated diol is reacted is converted into a leaving group and reacted with an number of nucleophiles. Complexes of the fluorinated compounds that as useful in Magnetic Resonance Imaging are also provided.

专利号:US-7932311-B2
优先权日:2005-12-23
标题 :Synthesis of particles in dendritic structures
发明人:AYMONIER CYRIL; CANSELL FRANCOIS; MECKING STEFAN; MOISAN SANDY; MARTINEZ VICTOR
权利人:CENTRE NAT RECH SCIENT
摘要:The invention relates to a method of preparing a particle-based composition, comprising: (i) bringing into contact a mixture comprising a dendritic structure and a metal compound precursor in a fluid, under temperature and pressure conditions such that the mixture is not soluble in the fluid; and (ii) chemically converting the metal compound precursor.

专利号:US-9175026-B2
优先权日:2011-03-23
标题:Synthesis of thioether containing trialkoxysilanes
发明人:GARRELL ROBIN L; TUCKER-SCHWARTZ ALEXANDER K
权利人:GARRELL ROBIN L; TUCKER-SCHWARTZ ALEXANDER K; UNIV CALIFORNIA
摘要:The invention relates to a radical-initiated thiol-ene or thiol-yne “clickâ€? reaction that provides a simple and efficient route to diverse trialkoxysilanes. Trialkoxysilanes made in this way are obtained in quantitative to near-quantitative yields with high purity without any or minimal purification. A wide range of functional groups is tolerated in this approach, and even complex alkenes click with the silane precursors. The modular nature of these radical-based thiol-ene or thiol-yne “clickâ€? reactions allows a wide variety of pendant groups to be coupled to silane compounds that can then be coupled to a wide variety surfaces in order to modify their material properties. Consequently, such radical initiated thiol-ene and thiol-yne reactions provide facile and efficient methods for preparing an enormous number of surface-active functional trialkoxysilanes.

专利号:US-6822121-B2
优先权日:2000-06-07
标题:Production process of cyclohexenyl ketones
发明人:WATANABE SHINYA; UJIHARA HIDEO; YAMAMOTO TAKESHI; HAGIWARA TOSHIMITSU
权利人:TAKASAGO PERFUMERY CO LTD
摘要:An economical process for producing (2- and/or 1-)cyclohexenyl methyl ketones which are intermediates for the synthesis of alpha- or beta-damascone. In the presence of a catalyst, a 3-cyclohexenyl methyl ketone represented by the following formula (1a):wherein, R1, R2 and R3 each independently represents a hydrogen atom or a methyl group and at least two of R1, R2 and R3 are methyl groups, is isomerized.

专利号:US-10787576-B2
优先权日:2015-04-30
标 题 :Method for the preparation of a coating comprising oligomeric alkynes
发明人:FRAUENRATH HOLGER; SCHRETTL STEPHEN; SCHULTE BJOERN; LETERRIER YVES
权利人:ECOLE POLYTECHNIQUE FED DE LAUSANNE EPFL EPFL TTO
摘要:The invention relates to a method for the preparation of a coating comprising at least one coating layer on a substrate, the method comprising the steps of a. providing monomers of the type R—(N) x -(L) m -(Câ•?C) n -(L′) o -(N′) y —R′, wherein R is a head moiety, R′ is a tail moiety, (C≡C) n is an oligoyne moiety, L and L′ are linker moieties, N and N′ independently are branched or unbranched optionally substituted C 1 -C 25 alkyl moieties optionally containing 1 to 5 heteroatoms, x, m, o, and y are independently 0 or 1, n is 4 to 12, and wherein the head moiety allows for an interaction with the surface of the substrate; b. bringing the monomers into contact with the substrate wherein the interaction of the head moieties of the monomers with the surface of the substrate induces at least a part of the monomers to align in a defined manner thereby forming a film on the surface and bringing the oligoyne moieties of the monomers into close contact with each other; c. inducing a reaction between oligoyne moieties by providing an external stimulus so as to at least partially cross-link the aligned monomers, thereby forming a coating layer on the substrate. The invention further relates to a coating obtainable according to the method of the invention, the use of a coating obtainable according to the method of the invention, a substrate comprising a coating obtainable according to the invention and the use of solid substrate. The invention further relates to a method for the synthesis ofthe monomers according to the invention.
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主要参考文献


1: Brown A, Patel S, Ward C, Lorenz A, Ortiz M, DuRoss A, Wieghardt F, Esch A, Otten EG, Heiser LM, Korolchuk VI, Sun C, Sarkar S, Sahay G. PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder. Sci Rep. 2016 Aug 30;6:31750. doi: 10.1038/srep31750.
2: Saifer MG, Williams LD, Sobczyk MA, Michaels SJ, Sherman MR. Selectivity of binding of PEGs and PEG-like oligomers to anti-PEG antibodies induced by methoxyPEG-proteins. Mol Immunol. 2014 Feb;57(2):236-46. doi: 10.1016/j.molimm.2013.07.014. Epub 2013 Nov 5. doi: 10.1517/17425247.2012.720969. Epub 2012 Aug 30.

合成参考文献


摘要:International Journal of Toxicology 31(Suppl. 2):169-244, 2012
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