专利号:US-9957355-B2 优先权日:2013-06-12 标 题 :Device and method for synthesis of a polymer under separation of a gaseous substance 发明人:ZHU NING; STAMMER ACHIM; CLAUSS JOACHIM; KORY GAD 权利人:BASF SE 摘要:The invention relates to a device for synthesis of a polymer under separation of a gaseous substance. Said device comprises a reaction chamber ( 1 ), which has a top section ( 11 ), a middle section ( 12 ) and a bottom section ( 13 ), an inlet opening ( 2 ) which is arranged in the middle section ( 12 ), a first outlet opening ( 3 ) which is arranged in the bottom section ( 13 ), a second outlet opening ( 4 ) which is arranged in the top section ( 11 ), a first return opening ( 51 ), which is arranged in the bottom section ( 13 ), a second outlet opening ( 52 ), which is arranged under the top section ( 11 ), a distribution device ( 6 ), which is arranged between the top section ( 11 ) and the middle section ( 12 ), and a removal device ( 7 ) which is arranged to be movable along the top section ( 11 ). The invention further relates to a method for synthesis of a polymer which can be carried out in said device.
专利号:US-9631051-B2 优先权日:2013-06-12 标 题:Device for the synthesis of a polymer with extraction of a gaseous substance comprising a reaction chamber having at least one circular-cylindrical section 发明人:ZHU NING; STAMMER ACHIM; CLAUSS JOACHIM; KORY GAD 权利人:BASF SE 摘要:An apparatus for synthesis of a polymer with separation of a gaseous substance comprises a reaction space having an essentially circular cylindrical upper section which is bounded by two circular faces and one shell face and has a longitudinal cylinder axis, and a lower section, an inlet orifice disposed in a circular face or the shell face of the upper section, a first outlet orifice disposed in a wall of the lower section, a second outlet orifice disposed in the shell face of the upper section opposite the first outlet orifice, and a removal device which is disposed so as to be rotatable about the longitudinal cylinder axis and is in contact with both circular faces and the shell face. This apparatus can especially be used for performance of a process including the feeding of an oligomer melt into a reaction space through an inlet orifice, the polymerization of the oligomer melt to give a polymer melt, the removal of the polymer melt from the reaction space through a first outlet orifice of the reaction space, and the removal of a gaseous substance from the reaction space through a second outlet orifice of the reaction space, wherein deposits on at least one inner wall of the reaction space are removed by a removal device and transported into the oligomer melt.
专利号:US-10759899-B2 优先权日:2017-08-03 标题 :Recyclable polymers based on ring-fused gamma-butyrolactones 发明人:CHEN EUGENE Y; Zhu jian-bo 权利人:UNIV COLORADO STATE RES FOUND 摘要:The invention discloses a class of new polymers, trans-ring-fused poly(4-hydroxybutyrate)s (RF-P4HB) that exhibit a unique set of properties, including robust thermal stability and mechanical strength, quantitative recyclability to the building block monomers via thermolysis and/or chemical catalysis, and convenient production from the chemical ring-opening polymerization under ambient temperature and pressure. Another unique property is the formation of crystalline stereocomplexed polymers with high melting temperature upon mixing the two enantiomeric RF-P4HB chains via stereocomplexing co-crystallization. This invention also provides the corresponding ring-fused lactone monomer structures that enable the synthesis of the RF-P4HB polymers, through trans-fusing of rings to the parent γ-butyrolactone ring. Furthermore, a polymerization or copolymerization process for the synthesis of RF-P4HB polymers and copolymers is disclosed.
专利号:US-2009111737-A1 优先权日:1999-05-24 标题:Novel antibacterial agents 发明人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES 权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES 摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.
专利号:WO-2020027845-A1 优先权日:2018-08-02 标 题 :Recyclable polymers based on ring-fused gamma-butyrolactones 发明人:CHEN EUGENE Y; Zhu jian-bo 权利人:UNIV COLORADO STATE RES FOUND; CHEN EUGENE Y; Zhu jian bo 摘要:The invention discloses a class of new polymers, trans-ring-fused poly(4-hydroxybutyrate)s (RF-P4HB) that exhibit a unique set of properties, including robust thermal stability and mechanical strength, quantitative recyclability to the building block monomers via thermolysis and/or chemical catalysis, and convenient production from the chemical ring-opening polymerization under ambient temperature and pressure. Another unique property is the formation of crystalline stereocomplexed polymers with high melting temperature upon mixing the two enantiomeric RF-P4HB chains via stereocomplexing co-crystallization. This invention also provides the corresponding ring-fused lactone monomer structures that enable the synthesis of the RF-P4HB polymers, through trans -fusing of rings to the parent γ-butyrolactone ring. Furthermore, a polymerization or copolymerization process for the synthesis of RF-P4HB polymers and copolymers is disclosed.
专利号:US-2013203898-A1 优先权日:2012-02-03 标 题:Hyperbranched polymers for modifying the toughness of cured epoxy resin systems 发明人:MUELLER-CRISTADORO ANNA; STUMBE JEAN-FRANCOIS; SCHERR GUENTER; HENNINGSEN MICHAEL; BRUCHMANN BERND; HABERECHT MONIKA; YU MIRAN; YIN CHUNHONG; KAFFEE ACHIM 权利人:MUELLER-CRISTADORO ANNA; STUMBE JEAN-FRANCOIS; SCHERR GUENTER; HENNINGSEN MICHAEL; BRUCHMANN BERND; HABERECHT MONIKA; YU MIRAN; YIN CHUNHONG; KAFFEE ACHIM 摘要:The invention relates to a curable composition comprising one or more epoxy compounds, one or more amino hardeners, and an addition of one or more dendritic polymers selected from the group of the dendritic polyester polymers, where the dendritic polyester polymers can be produced through an Ax+By synthesis route.
[参考文献]: B A Jnsson, Et Al. Generation Of Hexahydrophthalic Anhydride Atmospheres In A Controlled Human-Use Test Chamber. Am Ind Hyg Assoc J. 1994 Apr;55(4):330-8. [参考文献]: B A Jnsson, Et Al. Occupational Exposure To Hexahydrophthalic Anhydride: Air Analysis, Percutaneous Absorption, And Biological Monitoring. Int Arch Occup Environ Health. 1993;65(1):43-7. [参考文献]: B A Jnsson, Et Al. Toxicokinetics And Biological Monitoring In Experimental Exposure Of Humans To Gaseous Hexahydrophthalic Anhydride. Scand J Work Environ Health. 1993 Jun;19(3):183-90. [参考文献]: B Jnsson, Et Al. Method For The Biological Monitoring Of Hexahydrophthalic Anhydride By The Determination Of Hexahydrophthalic Acid In Urine Using Gas Chromatography And Selected-Ion Monitoring. J Chromatogr. 1991 Dec 6;572(1-2):117-31. [参考文献]: C H Lindh, Et Al. Determination Of Hexahydrophthalic Acid And Methylhexahydrophthalic Acid In Plasma After Derivatisation With Pentafluorobenzyl Bromide Using Gas Chromatography And Mass Spectrometric Detection. J Chromatogr B Biomed Sci Appl. 1997 Apr 11;691(2):331-9.
合成参考文献
摘要:J. Sicher, F. Sipos and J. Jonas, Collect. Czech. Chem. Commun. 26, 262 (1961). 摘要:H. Christol and M. Gaignon, J. Chim. Phys. Phys.-Chim. Biol. 57, 707 (1960).