CAS: 1617-49-8; 2,3,8-Tri-O-Methylellagic Acid

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CAS号100-44-7 氯化苄

📜3,3',4'-Tri-O-Methylellagic Acid 4-O-[α-L-Rhamnopyranosyl-(1->2)]-β-D-Glucopyranoside置于盐酸,水体系中,用 甲醇 用作溶剂,化学反应 3.0H,反应生成2,3,8-三邻甲基鞣花酸
参考文献:来自 Pancovia Pedicellaris 的抗菌鞣花酸衍生物和其他成分
标题:来自 Pancovia Pedicellaris 的抗菌鞣花酸衍生物和其他成分
摘要:从 Pancovia Pedicellaris 中分离出两种新的鞣花酸衍生物,命名为 Panconosides A (1) 和 B(2),以及 11 种已知化合物 (3-13).1 和 2 的结构以及已知化合物的结构是通过光谱方法并通过与先前报道的数据进行比较来确定的.在体外测试了化合物 1 和 2 对六种微生物的抗菌潜力:藤黄微球菌,金链球菌,小链球菌,大肠杆菌,枯草芽孢杆菌和琼脂假单胞菌.与标准药物相比,它们被发现对所有测试的菌株表现出中等的抗菌活性.Pancovia Pedicellaris 的图形摘要抗菌鞣花酸衍生物和其他成分
Doi:10.1515/znb-2009-0913

专利信息

专利号:US-2002165207-A1
优先权日:2001-05-02
标题 :Compositions and methods for the treatment of diabetic neuropathy
发明人：ROSENBLOOM RICHARD
摘要:Compositions and a method for the treatment of diabetic neuropathy is disclosed. The compositions comprise a mixture of a compound that promotes synthesis of nerve growth factor, an aldose reductase inhibitor and an antioxidant, optionally formulated in a pharmaceutically acceptable carrier. This combination of active agents provides significant, effective relief of the symptoms of diabetic neuropathy, as well as at least partial recovery of lost neurological function in some cases. In addition, the compositions of the present invention, when used in effective amounts to treat diabetic neuropathy, do not exhibit the severe side effects of many prior art compositions proposed for treatment of this ailment. n In a second aspect, a method for the administration of a composition in accordance with the present invention for the treatment of diabetic neuropathy is disclosed. In the method, an effective amount of the composition of the invention is administered on a regular basis over a period of time sufficient to provide the beneficial effects of relief from the symptoms of diabetic neuropathy, as well as at least some recovery of the damaged nerve tissues.

专利号:US-7914823-B2
优先权日:2000-12-21
标题 :Method and composition for the topical treatment of diabetic neuropathy
发明人：ROSENBLOOM RICHARD ALLEN
权利人:PROPHASE LABS INC
摘要:A method and composition for the treatment of diabetic neuropathy is disclosed. The composition comprises a cold compounded mixture of a compound that promotes synthesis of nerve growth factor, an aldose reductase inhibitor and an antioxidant formulated in a pharmaceutically acceptable carrier. It has been found that this combination of active agents provides significant, effective relief of the symptoms of diabetic neuropathy, as well as at least partial recovery of lost neurological function in some cases. In view of the consensus in the art that effective combinations of various active agents have not been demonstrated to be effective for the treatment of diabetic neuropathy, the present invention provides a surprising and unexpected effect. In addition, the topical compositions of the present invention, when used in effective amounts to treat diabetic neuropathy, do not exhibit the severe side effects of many prior art compositions proposed for treatment of this ailment. n In a second aspect, a method for the topical administration of a composition in accordance with the present invention for the treatment of diabetic neuropathy is disclosed. In the method, an effective amount of the composition of the invention is topically administered to the areas of the body that have been adversely affected by the diabetic neuropathy on a regular basis over a period of time sufficient to provide the beneficial effects of relief from the symptoms and at least some recovery of the damaged nerve tissues.