CAS: 1464-33-1; 5-(Hydroxymethyl)-4-(Methoxymethyl)-2-Methylpyridin-3-Ol

该化合物是pyridoxine(vitamin B6)的衍生物,其特征是:在环的4欧元位置上存在一个甲氧基组,这种改变可影响其溶性,稳定性和生物活动,与其母体化合物相比,这种物质一般是白色的,非白色的晶状粉,在有机溶剂中溶解,但水溶解性有限. 4 欧元-O-甲基丙烯酮在生物化学研究中很受关注,因为它在代谢工艺中的潜在作用及其对酶活动的影响.它可能表现出抗氧化性,并可能参与各种生理功能,包括氨酸代谢和...

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CAS号67-56-1 甲醇 | CAS号65-23-6 维生素B6 | CAS号65-23-6 维生素B6

合成工艺路线路线简述

    📜3-Hydroxy-5-Hydroxymethyl-4-Methyxymethyl-2-Methylpyridine 3-O-β-D-Glucopyranoside 反应生成5-羟基-4-甲氧甲基-6-甲基-3-吡啶甲醇
    参考文献:Orsini,Fulvia;Pelizzoni,Francesca;Pulici,Maurizio;Verotta,Luisella,Gazz. Chim. Ital.,119,(1989) N,C. 63-64
    标题:Orsini,Fulvia;Pelizzoni,Francesca;Pulici,Maurizio;Verotta,Luisella,Gazz. Chim. Ital.,119,(1989) N,C. 63-64

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    专利信息


    专利号:US-2005287169-A1
    优先权日:2003-06-17
    标 题 :Methods of use of genes of pyridoxal 5'-phosphate biosynthesis in Bacillus subtilis: avirulent strains for vaccines, and methods for identification of antibacterial agents
    发明人:BELITSKY BORIS R
    权利人:BELITSKY BORIS R
    摘要:Methods and compositions comprising a pathogenic bacterial strain having a non-reverting mutation in a pdx gene encoding an enzyme involved in pyridoxal-5′-phosphate synthesis are provided, for use in vaccines, and methods for identification of inhibitors of the enzyme for use as an antibacterial agent are provided.

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    主要参考文献


    1: Zou M, Zhang W, Dong Q, Tang C, Cao F, Su E. Submerged fermentation of Ginkgo biloba seed powder using Eurotium cristatum for the development of ginkgo seeds fermented products. J Sci Food Agric. 2020 Sep 6. doi: 10.1002/jsfa.10792. Epub ahead of print. 59(12):1555-1558. doi: 10.2169/internalmedicine.4196-19. Epub 2020 Mar 5.
    4: Are S, Gatreddi S, Jakkula P, Qureshi IA. Structural attributes and substrate specificity of pyridoxal kinase from Leishmania donovani. Int J Biol Macromol. 2020 Jun 1;152:812-827. doi: 10.1016/j.ijbiomac.2020.02.257. Epub 2020 Feb 24.
    2020:5072954. doi: 10.1155/2020/5072954.

    合成参考文献


    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
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