CAS: 115-32-2; Dicofol

该化合物是一种有机氯化合物,主要用作农药,特别是用于控制各种作物的,其特点是化学结构,包括一个氯化酚类,有助于其作为杀螨剂的功效.三氯杀螨醇一般是无色的,可粉黄,有微弱的气味,在正常条件下相对稳定.在水中表现出低溶性,但可溶于有机溶剂,便于其在农业环境中应用.该化合物对水生生物具有中度至高毒性,引起人们对使用该化合物的环境问题的关注.此外,三氯杀螨醇在食物链中生物累积,导致潜在的长期生态影响.多年来,由于在环境中的持久性以及对人类和野生动物的潜在健康风险,监管性审查增加了.结果,一些国家限制或禁止使用该物质,从而促使在虫害管理中寻找更安全的替代品.

结构式图片

欧盟法规

欧盟《事先知情同意法规》附件五《欧盟PIC法规》统一分类与标签ECHA物质工作场所安全标识要求ECHA物质OtherC&L通报欧盟《水框架指令》附件XREACH预注册废弃物危险特性清单

上下游产品

CAS号3563-45-9 氯化滴滴涕 | CAS号3567-16-6 [2,2,2-trichlor... | CAS号90-98-2 4,4'-二氯二苯甲酮 | CAS号67-66-3 氯仿 | CAS号3567-18-8 4,4'-dichloro-a... | CAS号39144-63-3 methyl chlorobe... | CAS号3547-04-4 1-chloro-4-[1-(... | CAS号81012-95-5 Acetamide,N-[2,...

合成工艺路线路线简述

  • 合成目标产物 Dicofol 主要起始原料 4,4'-Ddt
  • (文献来源)合成步骤主要原料 4,4'-Ddt
📜氯化滴滴涕置于硫酸,对甲苯磺酸体系中,化学反应生成三氯杀螨醇
参考文献:Preparation Of Bis (Chlorophenyl)-Trichloroethanol
标题:Preparation Of Bis (Chlorophenyl)-Trichloroethanol

海关参考信息

专利信息


专利号:US-6770436-B1
优先权日:1996-11-14
标题:Chemical amplification for the synthesis of patterned arrays
发明人:BEECHER JODY E; GOLDBERG MARTIN J; MCGALL GLENN H
权利人:AFFYMETRIX INC
摘要:Radiation-activated catalysts (RACs), autocatalytic reactions, and protective groups are employed to achieve a highly sensitive, high resolution, radiation directed combinatorial synthesis of pattern arrays of diverse polymers. When irradiated, RACs produce catalysts that can react with enhancers, such as those involved in autocatalytic reactions. The autocatalytic reactions produce at least one product that removes protecting groups from synthesis intermediates. This invention has a wide variety of applications and is particularly useful for the solid phase combinatorial synthesis of polymers.

专利号:US-2004110133-A1
优先权日:2002-12-06
标 题 :Functionated photoacid generator for biological microarray synthesis
发明人:XU GUANGYU; GOLDBERG MARTIN
权利人:AFFYMETRIX INC
摘要:In some embodiment of the invention, methods are provided for the synthesis of polymer arrays. In one embodiment, a chemically amplified polymer matrix is used for the synthesis of polymer arrays.

专利号:US-7053198-B2
优先权日:2002-12-06
标题 :Functionated photoacid generator and functionated polymer system for biological microarray synthesis
发明人:GOLDBERG MARTIN; XU GUANGYU
权利人:AFFYMETRIX INC
摘要:In some embodiment of the invention, methods are provided for the synthesis of polymer arrays. In one embodiment, a reactive polymer and a photo acid generator is used for the photodirected polymer array synthesis.

专利号:US-5245091-A
优先权日:1990-06-22
标 题 :Process for the preparation of 1,1-bis(chlorophenyl)-2,2,2-trichloroethanol
发明人:CASTELLA SOLA JAUME; PALENCIA ADRUBAU JAIME; COMMANDEUR RAYMOND; GORNY BERNARD
权利人:ATOCHEM ELF SA
摘要:The invention relates to a process for the synthesis of 1,1-bis(chlorophenyl)-2,2,2-trichloroethanol in (dicofol) from chlorol and chlorobenzene, in which process the acid by-products formed during the condensation reaction of the chloral and the chlorobenzene are used as reaction medium in the final step for synthesis of dicofol.

专利号:WO-2025056767-A1
优先权日:2023-09-15
标题 :Process for the preparation of enantiomerically enriched aliphatic amines
发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
权利人:SYNGENTA CROP PROTECTION AG
摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

专利号:US-2016073631-A1
优先权日:2013-03-04
标 题 :Process for the preparation of dihydropyrrole derivatives
发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
权利人:SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) n n n n n n n n n n n n wherein n P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; n R 1 is chlorodifluoromethyl or trifluoromethyl; n R 2 is optionally substituted aryl or optionally substituted heteroaryl; n n is 0 or 1; n including the process comprising n (a-i) reacting a compound of formula II n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; n with nitromethane in the presence a chiral catalyst to give a compound of formula III n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; and n (a-ii) reductively cyclising the compound of formula III to give the compound of formula I. n n n n n The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献


1: Wang Z, Yang T, Zhai Z, Zhang B, Zhang J. Reaction mechanism of dicofol removal by cellulase. J Environ Sci (China). 2015 Oct 1;36:22-8. doi: 10.1016/j.jes.2015.03.015. Epub 2015 Jun 13. doi: 10.1021/es502092x. Epub 2014 Dec 15. doi: 10.1016/j.foodchem.2014.04.023. Epub 2014 Apr 13. doi: 10.1016/j.jes.2014.12.023. Epub 2015 May 12. doi: 10.1016/j.scitotenv.2013.08.043. Epub 2013 Sep 9. doi: 10.1016/j.chemosphere.2013.09.090. Epub 2013 Oct 22. doi: 10.1016/j.chroma.2014.07.102. Epub 2014 Aug 7. doi: 10.1016/j.chroma.2013.07.054. Epub 2013 Jul 19. doi: 10.1016/j.tox.2011.01.016. Epub 2011 Feb 1. doi: 10.1016/j.talanta.2011.07.061. Epub 2011 Jul 23. doi: 10.1016/j.chemosphere.2010.10.036. Epub 2010 Nov 3. doi: 10.1016/j.jenvman.2010.08.008. Epub 2010 Sep 1. doi: 10.1021/jf400847b. Epub 2013 Mar 11. doi: 10.1089/hyb.2010.0051. Epub 2010 Nov 30. doi: 10.1002/etc.274. doi: 10.1016/j.saa.2011.12.070. Epub 2011 Dec 31. doi: 10.1002/jssc.201600258. Epub 2016 May 24. doi: 10.1007/s10661-010-1863-z. Epub 2011 Jan 21.

合成参考文献


参考文献:10.1007/s11356-011-0561-x
摘要:Turgut C, Atatanir L, Mazmanci B, Mazmanci MA, Henkelmann B, Schramm K. The occurrence and environmental effect of persistent organic pollutants (POPs) in Taurus Mountains soils. Environmental Science and Pollution Research. 2011 Jul 13;19(2):325–34. doi: 10.1007/s11356-011-0561-x.
参考文献:10.3390/ijerph8062265
摘要:Mnif W, Hassine AI, Bouaziz A, Bartegi A, Thomas O, Roig B. Effect of endocrine disruptor pesticides: a review. Int J Environ Res Public Health. 2011 Jun;8(6):2265–303.
参考文献:10.1007/s10493-005-2647-y
摘要:Villa JD, Danka RG. Caste, Sex and Strain of Honey Bees (Apis mellifera) Affect Infestation with Tracheal Mites (Acarapis woodi)*. Experimental and Applied Acarology. 2005 Dec;37(3-4):157. doi: 10.1007/s10493-005-2647-y.
参考文献:10.1007/s10493-005-1423-3
摘要:Pree DJ, Whitty KJ, Van Driel L. Baseline Susceptibility and Cross Resistances of Some New Acaricides in the European Red Mite, Panonychus ulmi*. Experimental and Applied Acarology. 2005 Dec;37(3-4):165. doi: 10.1007/s10493-005-1423-3.
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