专利号:WO-9219616-A1 优先权日:1991-05-06 标题 :Improvements of a pesticidal/insect repellent comprising synthesis of a new pesticidal insect repellent 发明人:GUERRINI VINCENT HENRY 权利人:GUERRINI VINCENT HENRY 摘要:There is provided a novel method to improve the pesticidal and repellent properties of neem extracts or azadirachtin containing compositions comprising the synthesis of a new pesticide repellent. Neem extracts containing azadirachtins or compositions containing neem extracts or neem extracts with azadirachtins, dialkyltoluamides and volatile oils are heated between 30 and 200 degrees centigrade from 1 second to 1000 hours to improve the pesticidal and repellent properties of the compositions or synthesize new pesticides or insect repellents.
专利号:WO-2013001322-A1 优先权日:2011-06-30 标 题:PROCESS FOR THE SYNTHESIS OF (5α,17β)-N-[(2,5-BIS(TRIFLUOROMETHYL)-PHENYL]-3-OXO-4-AZA-5-ANDROST-1-ENE-17-CARBOXAMIDE 发明人:SOEROES BELA; TUBA ZOLTAN; GALIK GYOERGY; MAHO SANDOR; BALOGH LASZLO; VINCZE PETER; HORVATH JANOS; KOVACS ANDRAS; BENI ZOLTAN; VARGA FRIGYES 权利人:RICHTER GEDEON NYRT; SOEROES BELA; TUBA ZOLTAN; GALIK GYOERGY; MAHO SANDOR; BALOGH LASZLO; VINCZE PETER; HORVATH JANOS; KOVACS ANDRAS; BENI ZOLTAN; VARGA FRIGYES 摘要:The synthesis consists of reaction steps as follows: oxidizing the α,β-unsaturated ketone system of ring 'A' of pregn-4-ene-3,20-dion- of formula (II) with sodium metaperiodate in tert-butanol in the presence of potassium permanganate and alkali metal carbonate, reacting the obtained 3,5-seco acid with an ester of chloroformic acid in the presence of tertier organic base below 0°C, reacting the obtained new compound after isolation or without isolation with ammonia or ammonium acetate, cyclization of the resulting carboxamides with an acid, cathalytic hydrogenating the obtained ene lactame, and oxidizing the side chain at position 17 of the obtained pregnane compound with an alkali metal hypobromide in aqueous dioxane below 10°C. Thereafter on one hand the obtained (5α,17β)-3-oxo-4-aza-5-androstane-17-carboxylic acid is reacted with chloroformic acid ester, the obtained new compound is reacted with 2,5-bis(trifluoromethyl)-aniline in the presence of a Lewis acid, the obtained amide is reacted with trimethyl chlorosilane in inert atmosphere in the presence of Î?,Î?,Î?',Î?'-tetramethyl-ethylendiamine, then en excess iodine is added to the reaction mixture and the product of the iodination reaction is crystallized from acetonitrile, then the obtained 2-iodo-3-oxo-4-aza-17β-carboxamide is reacted with potassium tert-butylate to furnish final product. On the other hand, (5α,17β)-3-oxo-4-aza-5-androstane-17-carboxylic acid is transformed into methylester by known method, this latter is transformed into methyl (2α,5α,17β)-2-iodo-3-oxo-4-aza-5-androstane-17-carboxylate according to known method, the obtained compound is reacted with potassium-tert-butylate, the obtained (5α,17β)-3-oxo-4-aza-5-androst-1-ene-17-carboxylic acid is reacted with an ester of chloroformic acid, then the obtained new compound is coupled with 2,5-bis(trifluoromethyl)-aniline in the presence of a Lewis acidcatalyst to gain final product.
专利号:US-9750259-B2 优先权日:2014-11-24 标题:Pyroxasulfone and glutamine synthesis inhibitor compositions for weed control 发明人:REFSELL DAWN 权利人:VALENT U S A; VALENT USA CORP 摘要:The present invention is directed to compositions containing herbicidal mixtures of pyroxasulfone and glutamine synthesis inhibitors. The present invention is further directed to methods of increasing the activity of a glutamine synthesis inhibitor with the compositions of the present invention.
专利号:CN-114989235-A 优先权日:2015-09-28 标题:Design and synthesis of nucleotides based on novel disulfide linkers for use as reversible terminators for DNA sequencing by synthesis
专利号:US-9999223-B2 优先权日:2008-05-21 标 题 :Herbicidal composition comprising glyphosate, glufosinate or their salts 发明人:SIEVERNICH BERND; MOBERG WILLIAM KARL; SIMON ANJA; WALTER HELMUT; EVANS RICHARD R 权利人:BASF SE 摘要:The present invention relates to a herbicidal composition which comprises:n a) at least one herbicide A selected from glyphosate, glufosinate and their salts, and b) a herbicide B which is 3-[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)pyrazol-4-ylmethylsulfonyl]-4,5-dihydro-5,5-dimethyl-1,2-oxazole [common name: pyroxasulfone]. nn The present invention relates in particular to a herbicidal composition comprising:n a) at least one herbicide A selected from glyphosate, glufosinate and their salts, b) a herbicide B which is 3-[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)pyrazol-4-ylmethylsulfonyl]-4,5-dihydro-5,5-dimethyl-1,2-oxazole [common name: pyroxasulfone], and c) at least one further herbicide C, which is selected from the herbicide groups C.1 to C.8:n C.1 herbicides of the group of acetolactate synthase inhibitors (ALS inhibitors), C.2 herbicides of the group of protoporphyrinogen oxidase inhibitors (PPO inhibitors), C.3 herbicides of the group of auxines, C.4 herbicides of the group of 4-hydroxyphenyl-pyruvate-dioxygenase inhibitors (HPPD inhibitors), C.5 herbicides of the group of phytoene desaturase inhibitors (PDS inhibitors), C.6 herbicides of the group of photosystem II inhibitors (PSII inhibitors), C.7 herbicides of the group of microtubulin inhibitors, and C.8 herbicides of the group of inhibitors of the synthesis of very long chain fatty acids (VLCFA inhibitors).
专利号:US-2003082830-A1 优先权日:1996-10-16 标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products
1. Kilsheimer, J.A., and Kaufman, H.A. Pesticidal composition comprising a benzothienyl carbamate and synergist. (1972). 2. Radwan, H.S.A., Riskallah, M.R., and El-Keie, I.A. Synergistic effects on the toxicity of organotins on cotton leafworms. Toxicology 14(3), 193-198 (1979). 3. Singh, K., and Singh, D.K. Effect of different combinations of MGK-264 or piperonyl butoxide with plant-derived molluscicides on snail reproduction. Arch. Environ. Contam. Toxicol. 38(2), 182-190 (2000).
合成参考文献
摘要:Special Publication of the Entomological Society of America., 78-1(5), 1978 摘要:Rodil R et al; Chemosphere 86: 1040-9 (2012) 摘要:Official Methods of Analysis of AOAC International, 18th Edition Online. MGK 264 (113-48-4). Available from, as of February 8, 2011: 摘要:US EPA; Estimation Program Interface (EPI) Suite. Ver. 4.1. Nov, 2012. Available from, as of July 11, 2017: 摘要:Kuney, J.H. and J.N. Mullican (eds). Chemcyclopedia. Washington, DC: American Chemical Society, 1984., p. 359