专利号:US-4565896-A 优先权日:1984-10-22 标 题 :Process for low pressure synthesis of ethylene glycol from synthesis gas 发明人:KNIFTON JOHN F; DURANLEAU ROGER G 权利人:TEXACO INC 摘要:This invention relates to the manufacture of ethylene glcyol and more particularly to a low pressure process for making ethylene glycol comprising reacting synthesis gas, i.e. a mixture of carbon monoxide and hydrogen, plus formaldehyde in the presence of a homogeneous liquid catalyst containing an effective amount of cobalt-containing compound and a silicon or germanium-containing promoter and a solvent at a temperature of at least 50 DEG C. and a pressure of at least 500 psi wherein said ethylene glycol product separates as a separate liquid phase from the solvent.
专利号:US-4568780-A 优先权日:1984-10-22 标 题 :Process for low pressure synthesis of ethylene glycol from synthesis gas plus 1,3-dioxolane 发明人:KNIFTON JOHN F 权利人:TEXACO INC 摘要:This invention relates to the manufacture of ethylene glycol and more particularly to a low pressure process for making ethylene glycol comprising reacting synthesis gas, i.e. a mixture of carbon monoxide and hydrogen, plus 1,3-dioxolane in the presence of a homogenous liquid catalyst containing an effective amount of cobalt-containing compound and a silane or germane-containing promoter dispersed in a hydrocarbon solvent at a temperature of at least 50 DEG C. and a pressure of at least 500 psi, where the particular solvents used allow the desired product to be separated from the reaction mixture by phase separation.
专利号:US-7019127-B2 优先权日:1997-08-13 标 题 :Solution phase synthesis of oligonucleotides 发明人:REESE COLIN BERNARD; SONG QUANLAI 权利人:AVECIA LTD 摘要:A process for the synthesis in solution phase of a phosphorothioate triester is provided. The process comprises the solution phase coupling of an H-phosphonate with an alcohol in the presence of a coupling agent to form an H-phosphonate diester. The H-phosphonate diester is oxidised in situ with a sulfur transfer agent to produce the phosphorothioate triester. Preferably, the H-phosphonate and alcohol are protected nucleosides or oligonucleotides. Oligonucleotide H-phosphonates which can be used in the formation of phosphorothioate triesters are also provided.
专利号:US-7129357-B2 优先权日:2003-09-15 标题:Synthesis of quinoline 5-carboxamides useful for the preparation of PDE IV inhibitors 发明人:ANDREWS DAVID R; TANG SUHAN; WU WENXUE; KALLINEY SAMI Y; SUDHAKAR ANANTHA; NIELSEN CHRISTOPHER 权利人:SCHERING CORP 摘要:In one embodiment, the present application discloses a process for making the compound of the formula:
专利号:US-9951095-B2 优先权日:2014-05-16 标 题:Chromium metal organic frameworks and synthesis of metal organic frameworks 发明人:ZHOU HONG-CAI; Liu tian-fu; LIAN XIZHEN; ZOU LANFANG; FENG DAWEI 权利人:TEXAS A & M UNIV SYS 摘要:The present invention relates to monocrystalline metal organic frameworks comprising chromium ions and carboxylate ligands and the use of the same, for example their use for storing a gas. The invention also relates to methods for preparing metal organic frameworks comprising chromium, titanium or iron ions and carboxylate ligands. The methods of the invention allow such metal organic frameworks to be prepared in monocrystalline or polycrystalline forms.
专利号:WO-9919297-A9 优先权日:1997-10-15 标题 :Synthesis of azetidine derivatives 发明人:CHEN ZHENGMING; KOLB HARTMUTH C; RICHARDSON PAUL; HUANG ZHI-MIN 权利人:COELACANTH CHEMICAL CORP; CHEN ZHENGMING; KOLB HARTMUTH C; RICHARDSON PAUL; HUANG ZHI MIN 摘要:The present invention provides compound having formula (I) useful as building blocks for combinatorial libraries and methods of making such compounds. Also provided are compositions comprising the compounds.
摘要:Song, Z.; Takahashi, T., Science of Synthesis Knowledge Updates, (2013) 1, 105. 摘要:Clark, K. F.; Dimitrova, D.; Murphy, J. A., Science of Synthesis, (2020) , 42. 摘要:Ghosh, I., Science of Synthesis: Photocatalysis in Organic Synthesis, (2018) 1, 415. 参考文献:10.1007/bf01369601 摘要:Imamura T, Kage S, Kudo K, Jitsufuchi N, Nagata T. A case of drowning linked to ingested sulfides — a report with animal experiments. International Journal of Legal Medicine. 1996 Mar;109(1):42–4. doi: 10.1007/bf01369601.