CAS: 56255-31-3; (S)-2-Palmitamidopropanoic Acid
该化合物是氨酸丙氨酸丙氨酸的脂肪酸衍生物,其特点是氨酸的长链脂肪丙酰(xadecanyny),具有独特的特性,分子具有独特的特性;该化合物的特征是其疏水尾,来自六十二硝酸(palmitic),它有助于其非phyphicical性质,使它能与水生生物和缺水环境互动;N-hexacony-aline经常在生物化学和分子生物学背景下研究,特别是因其在药物运载系统,表面活性剂和作为膜研究的模型化合物的潜在应用而研究;其结构影响其溶性,熔点和再活性,使其与各种化学和生物过程相关;此外,扬辛醇运动的存在可能影响其生物活动,包括与蛋白质和细胞膜相互作用;
- 英文名称(S)-2-Palmitamidopropanoic Acid
- 中文名称N-十六碳酰基-L-丙氨酸
- IUPAC名称palmitoyl-L-alanine
- 其它别名(S)-2-Palmitamidopropanoic Acid; N-Hexadecanoyl-Alanine; N-Hexadecanoyl-L-Alanine; 2-(1-Oxohexadecylamino)Propanoic Acid; L-Alanine, N-(1-Oxohexadecyl)-; (2S)-2-(Hexadecanoylamino)Propanoicaci; N-Hexadecanoyl-L-Alanine Usp/ep/bp; Codeage Pa
- CAS编号56255-31-3
- MFCD编号:MFCD00756938
- FDA UNII编号:68HNC9TLVC
- 分子式:C19H37NO3分子量:327.5
- 产品CID: 1535494
- 产品分类生物化工 → 氨基酸及其衍生物 → 丙氨酸类衍生物
上下游产品
CAS号81912-48-3 methyl N-hexade... | CAS号112-67-4 棕榈酰氯 | CAS号56-41-7 L-丙氨酸 | CAS号57-10-3 棕榈酸 | CAS号14464-31-4 棕榈酸N-羟基琥珀酰亚胺酯 | CAS号338-69-2 D-丙氨酸合成工艺路线路线简述
📜棕榈酰氯置于sodium Hydroxide,Potassium Hydrogencarbonate,三乙胺体系中,用 四氢呋喃,甲醇,氯仿,水 作为反应溶剂,化学反应 7.0H,反应生成 N-十六碳酰基-L-丙氨酸
参考文献:Molecular Mechanism Of Physical Gelation Of Hydrocarbons By Fatty Acid Amides Of Natural Amino Acids
标题:Molecular Mechanism Of Physical Gelation Of Hydrocarbons By Fatty Acid Amides Of Natural Amino Acids
摘要:A Variety Of Fatty Acid Amides Of Different Naturally occurring L-Amino Acids Have Been Synthesized And They Are Found To Form Gels With Various Hydrocarbons. The Gelation Properties Of These Compounds Were Studied By A Number Of Physical Methods Including Ftir Spectroscopy,X-Ray Diffraction,Scanning Electron Microscopy,Differential Scanning Calorimetry,Rheology,And It Was Found That Gelation Depended Critically On The Fatty Acid Chain Length And The Nature Of The Amino Acid. Among Them L-Alanine Based Gelators Were Found To Be The Most Efficient And Versatile Gelators As They Self-Assemble Into A Layered Structure To Form The Gel Network. Mechanisms For The Assembly And Formation Of Gels From These Molecules Are Discussed. (C) 2007 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Tet.2007.05.028
海关参考信息
- 2905121000-正丙醇
2912110000-甲醛
2912120000-乙醛
2915110000-甲酸 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
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主要参考文献
1: Musgrave RA, Choi P, Harniman RL, Richardson RM, Shen C, Whittell GR, Crassous J, Qiu H, Manners I. Chiral Transmission to Cationic Polycobaltocenes over Multiple Length Scales Using Anionic Surfactants. J Am Chem Soc. 2018 May 30. doi: 10.1021/jacs.8b03112. [Epub ahead of print] doi: 10.1007/s11095-018-2433-2. doi: 10.1016/j.cbpc.2018.03.003. Epub 2018 Mar 17. doi: 10.1155/2017/8641535. Epub 2017 Dec 26.
5: Fredericks GJ, Hoffmann FW, Hondal RJ, Rozovsky S, Urschitz J, Hoffmann PR. Selenoprotein K Increases Efficiency of DHHC6 Catalyzed Protein Palmitoylation by Stabilizing the Acyl-DHHC6 Intermediate. Antioxidants (Basel). 2017 Dec 29;7(1). pii: E4. doi: 10.3390/antiox7010004.
6: Kharbanda A, Runkle K, Wang W, Witze ES. Induced sensitivity to EGFR inhibitors is mediated by palmitoylated cysteine 1025 of EGFR and requires oncogenic Kras. Biochem Biophys Res Commun. 2017 Nov 4;493(1):213-219. doi: 10.1016/j.bbrc.2017.09.044. Epub 2017 Sep 9.
合成参考文献
摘要:International Journal of Toxicology 36(Suppl. 1):17-56, 2017
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