专利号:US-6229055-B1 优先权日:1996-04-12 标题 :Synthesis of fluorinated xanthene derivatives 发明人:KLAUBERT DIETER H; GEE KYLE R 权利人:MOLECULAR PROBES INC 摘要:Facile syntheses for fluorinated resorcinol and aminophenol derivatives are provided that yield isomer-free products in good yield. These novel methods use generally available precursors and standard laboratory reagents and equipment to reproducibly produce these synthetically useful reagents in relatively large quantities. The resulting fluorinated resorcinols and aniinophenols possess utility in the preparation of fluorinated fluorescein and rhodol dyes.
专利号:WO-2005113520-A1 优先权日:2004-05-20 标题 :Substituted 2,3,5-trifluorphenyl oxazolidinones for use as antibacterial agents 发明人:BARBACHYN MICHAEL ROBERT; HARRIS CHRISTINA RENEE; JOSYULA VARA PRASAD VENKATA NA 权利人:PHARMACIA & UPJOHN CO LLC; BARBACHYN MICHAEL ROBERT; HARRIS CHRISTINA RENEE; JOSYULA VARA PRASAD VENKATA NA 摘要:The present invention relates to trifluorphenyl oxazolidinones of formula (I) and to the process for the synthesis of the same. The compounds of the present invention are useful antimicrobial agents, effective against a number of human and veterinary pathogens.
专利号:US-2002077491-A1 优先权日:2000-09-05 标 题 :Methods for forming combinatorial libraries combining amide bond formation with epoxide opening 发明人:SHIPPS GERALD W; ROSNER KRISTIN E; MAKARA GERGELY M; WINTNER EDWARD A; NASH HUW M; FELSCH JASON S; PAL KOLLOL; LENZ GEORGE R 摘要:The invention relates to methods for forming combinatorial libraries. The invention provides methods suitable for the rapid and convenient synthesis of very large combinatorial libraries of small organic molecules. In particular, the invention provides a method for forming combinatorial libraries combining amide bond formation with epoxide opening.
专利号:US-2002115106-A1 优先权日:2000-12-22 标题 :Methods for forming combinatorial libraries using reductive amination 发明人:SHIPPS GERALD W; PAL KOLLOL 权利人:NEOGENESIS PHARMACEUTICALS INC 摘要:The invention relates to methods for forming combinatorial libraries. The invention provides methods suitable for the rapid and convenient synthesis of very large combinatorial libraries of small organic molecules. In particular, the invention provides a method for forming combinatorial libraries combining amide, sulfonamide, or urea bond formation with reductive amination.
专利号:CN-111377826-A 优先权日:2020-03-23 标 题 :A kind of green synthesis process of quinolone key intermediate
专利号:CN-111377826-B 优先权日:2020-03-23 标 题 :Green synthesis process of key intermediate of quinolone