CAS: 521973-99-9; Tert-Butyl 2-((4S,6R)-6-(Chloromethyl)-2,2-Dimethyl-1,3-Dioxan-4-yl)Acetate

该化合物是带有受保护碳基的手性中间体,广泛用于有机合成和制药应用,其主要优势包括:由于定义的(4S,6R)配置和反应性氯甲基组的存在,具有较高的立体化学纯度,能够进一步实现功能化;二氧烷环形结构具有僵硬性,在立体选择性反应中具有优势;该化合物在合成复杂分子方面特别有用,需要精确控制立体化和再活性;其坚固的结构使其适合多步合成途径.

英文名称Tert-Butyl 2-((4S,6R)-6-(Chloromethyl)-2,2-Dimethyl-1,3-Dioxan-4-yl)Acetate
中文名称罗舒伐他汀相关化合物6
IUPAC名称tert-butyl 2-((4S,6R)-6-(chloromethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
其它别名Rosuvastatin Related Compound 6; Rosuvastatin Impurity 93; Rosuvastatin Related Compound; 1,3-Dioxane-4-Acetic Acid, 6-(Chloromethyl)-2,2-Dimethyl-, 1,1-Dimethylethyl Ester, (4S,6R)-; Tert-Butyl 2-((4S,6R)-6-(Chloromethyl)-2,; Tert-Butyl 2-((4S,6R)-6-(Chloromethyl)-2,2-Dimethyl-1,3-Dioxan-4-yl)Acetate? (Rosuvastatin Impurity）
CAS编号521973-99-9
FDA UNII编号:A9TY3V37TB
分子式:C13H23ClO4分子量:278.78
产品CID: 1512842

相似结构搜索
InChIKey: TXLXWCARAPIXGH-VHSXEESVSA-N
InChI=1S/C13H23ClO4/c1-12(2,3)18-11(15)7-9-6-10(8-14)17-13(4,5)16-9/h9-10H,6-8H2,1-5H3/t9-,10+/m0/s1
计算化学: 氢键受体数*氢键供体数*可旋转键数*

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2,2-dimethoxy-propane 1,1-dimethylethyl (3R,5S)-6-chloro-3,5-dihydroxy-4-hexanoate tert-butyl (5S)-6-chloro-3,5-dihydroxyhexanoate tert-butyl acetoacetate[(4R,6S)-2,2-dimethyl-6-(1-phenyl-1H-tetrazole-5-sulfonylmethyl)[1,3]dioxan-4-yl]acetic acid tert-butyl ester tert-butyl 2-[(4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate (4R,6S)-(E)-{6-[2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-vinyl]-2,2-dimethyl-1,3-dioxan-4-yl}acetic acid tert-butyl ester (4R-cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester