CAS: 521-52-8; Methyl (E)-2-(3-Hydroxy-5-Oxo-4-Phenylfuran-2(5H)-Ylidene)-2-Phenylacetate

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CAS号79-37-8 草酰氯 | CAS号40195-27-5 Diethoxy(phenyl... | CAS号67-56-1 甲醇 | CAS号6273-79-6 Pulvinic anhydride | CAS号15206-55-0 苯甲酰甲酸甲酯 | CAS号57740-69-9 6-Benzyliden-3-... | CAS号6838-54-6 3-hydroxy-1,4-d... | CAS号548-59-4 2,5-Dihydroxy-3... | CAS号122-78-1 2-苯基乙醛 | CAS号26548-70-9 (αE)-α-[3-Hydro...

📜3-羟基-1,4-二苯基丁烷-2-酮置于sodium Hydroxide,溴,Sodium Ethanolate,乙酸酐,三溴化硼,三乙胺,1,5-Diazabicyclo[5.4.0]Undec-5-Ene体系中,用 四氢呋喃,乙醚,乙醇,正己烷,二氯甲烷,溶剂黄146,二甲基亚砜,N,N-二甲基甲酰胺,苯 作为反应溶剂,化学反应 8.08H,反应生成 吴耳酸
参考文献:Pattenden,Gerald; Pegg,Neil A.; Kenyon,Ronald W.,Journal Of The Chemical Society. Perkin Transactions I,1991,# 10,P. 2363-2372
标题:Pattenden,Gerald; Pegg,Neil A.; Kenyon,Ronald W.,Journal Of The Chemical Society. Perkin Transactions I,1991,# 10,P. 2363-2372

专利信息

专利号:US-8008459-B2
优先权日:2001-01-25
标 题 :Concatemers of differentially expressed multiple genes
发明人：GOLDSMITH NEIL; SORENSEN ALEXANDRA M P SANTANA; NIELSEN SOREN V S; NAESBY MICHAEL
权利人:EVOLVA SA
摘要:In the present invention are disclosed concatemers of concatenated expression cassettes and vectors that enable the synthesis of such concatemers. The concatemer comprises in the 5′→3′ direction a cassette of nucleotide sequence of the general formula [rs2-SP-PR-X-TR-SP-rs1]n wherein rs1 and rs2 together denote a functional restriction site, SP individually denotes a spacer of at least two nucleotide bases, PR denotes a promoter, capable of functioning in a cell, X denotes an expressible nucleotide sequence, TR denotes a terminator, and SP individually denotes a spacer of at least two nucleotide bases, and n>/=2, and wherein at least a first cassette is different from a second cassette. The main purpose of these concatemers is the controllable and co-ordinated expression of large numbers of heterologous genes in a single host. Furthermore, the invention relates to a concatemer of cassettes of nucleotide sequences and a method for preparing the concatemers. In a further aspect, the invention relates to transgenic host cells comprising at least one concatemer according to the invention, as well as to a method for preparing the transgenic host cells. Finally, the invention relates to a vector comprising a cassette of nucleotides, a method for preparing said vector, a nucleotide library comprising at least two primary vectors each comprising a cassette of nucleotides, a method for preparing the library.