CAS: 3368-16-9; 2-Propenoic Acid, 2,3-Diphenyl

该化合物是一种有机化合物,其结构特征是其结构,其特征是附于一个恶性酸碱的苯基组,该化合物一般是白色的至黄色的晶状固体,以其在有机合成中的作用和作为生产各种药品和农用化学产品的潜在中间体而著称. -苯丙胺酸在乙醇和丙酮等有机溶剂中表现出中等溶解性,同时在水中较不易溶解,其熔点和沸点可因纯度和特定条件而不同.该化合物具有酸性和芳香特性,允许其参与各种化学反应,包括化和聚合.此外,它可能展示生物活动,使其对医药化学具有兴趣.应当参考安全数据,以便处理,与所有化学物质一样,确保使用期间采取适当的预防措施.

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2,3-Diphenylacrylic Acid Methyl Ester
2-苯基丙烯酸 2-Phenylacrylic Acid 492-38-6

合成工艺路线路线简述

    📜2-苯基丙烯酸置于吡啶,Lithium Hydroxide Monohydrate,Palladium Diacetate,Potassium Carbonate,盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺体系中,用 乙醇,水,甲苯 作为反应溶剂,化学反应 57.0H,反应生成 Alpha-苯基-顺-肉桂酸
    参考文献:钯催化的8-氨基咪唑并[1,2-A]吡啶(aip)定向选择性β-C(sp2)-h芳基化
    标题:钯催化的8-氨基咪唑并[1,2-A]吡啶(aip)定向选择性β-C(sp2)-h芳基化
    摘要:本文首次报道了羧酸衍生物的惰性β-C(sp 2)-H键的钯催化的芳基化反应,首次使用8-氨基咪唑并[1,2-A]吡啶(aip)作为有效的新型内嵌化合物6,5-稠合的双环可移动导向基团.该协议是可扩展的,具有高水平的β-位点选择性,并能耐受各种官能团.
    DOI:10.1039/d0Ob02134B

    海关参考信息

    专利信息


    专利号:US-8101804-B2
    优先权日:2006-07-28
    标 题 :Process for the synthesis of (E)-stilbene derivatives which makes it possible to obtain resveratrol and piceatannol
    发明人:SCHOUTEETEN ALAIN; JUS SEBASTIEN; VALLEJOS JEAN-CLAUDE
    权利人:SCHOUTEETEN ALAIN; JUS SEBASTIEN; VALLEJOS JEAN-CLAUDE; CLARIANT SPECIALTY FINE CHEM F
    摘要:A subject-matter of the present invention is a novel process for the synthesis of (E)-stilbene derivatives targeted at obtaining in particular resveratrol and piceatannol.

    专利号:US-6764842-B2
    优先权日:2001-03-28
    标题 :Enantioselective bioreduction for the preparation of integrin receptor antagonist intermediates
    发明人:STURR MICHAEL G; BOYD RUSSELL FIELDON; GBEWONYO KODZO; NTI-GYABAAH JOSEPH; POLLARD DAVID J; MCWILLIAMS JAMES CHRISTOPHER; TELARI KATHLEEN A
    权利人:MERCK & CO INC
    摘要:The present invention relates to a novel enantioselective bioreduction using a yeast microorganism for the preparation of the chiral allylic alcohols of structural formula I (R is hydrogen or methyl) which are useful in the asymmetric synthesis of integrin αvβ 3 receptor antagonists.

    专利号:US-6531470-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-2010004483-A1
    优先权日:2006-07-28
    标 题 :Novel Process For The Synthesis Of (E)-Stilbene Derivatives Which Makes It Possible To Obtain Resveratrol And Piceatannol

    专利号:US-6562844-B2
    优先权日:1998-01-23
    标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:CA-2658652-A1
    优先权日:2006-07-28
    标 题 :Novel process for the synthesis of (e)-stilbene derivatives which makes it possible to obtain resveratrol and piceatannol

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Ager, D., Science of Synthesis: Stereoselective Synthesis, (2011) 1, 228.
    摘要:Takaya, J.; Iwasawa, N., Science of Synthesis: C-1 Building Blocks in Organic Synthesis, (2013) 1, 295.
    摘要:Tan, X.; Lv, H.; Zhang, X., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 1, 43.
    摘要:Hudson, R.; Moores, A., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 1, 72.
    摘要:Fujihara, T., Science of Synthesis: Special Topics, (2022) 1, 361.
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