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专利信息
专利号:US-6149924-A
优先权日:1998-07-20
标题 :Composition for enhancing lipid production, barrier function, hydrogen peroxide neutralization, and moisturization of the skin
发明人:PAUL HARBHAJAN S
权利人:BIOMED RES & TECHNOLOGIES INC
摘要:Increased production of skin lipids, increased barrier function, hydrogen peroxide neutralization, prevention of loss of the natural moisturizing factor from the stratum corneum and moisturization of the skin is provided by a topically applicable composition which includes one or more components selected from the group consisting of branched chain amino acids, derivatives of branched chain amino acids and mixtures thereof, which one or more components are capable of being catabolized in epidermal cells to form lipid precursors for epidermal lipid synthesis. The composition can also include one or more enzyme activators which increase the rate of catabolism of the one or more components.
专利号:CA-2640585-A1
优先权日:2003-02-05
标题 :Synthesis of 2-butyl-3-(2'-(1-trityl-1h-tetrazol-5-yl)biphenyl-4-yl)-1,3-diazaspirol{4,4}-non-ene-4-one
专利号:EP-0728471-B1
优先权日:1995-02-24
标题 :Cosmetic compositions for enhancing the collagen synthesis of the skin
专利号:US-5595730-A
优先权日:1994-12-20
标 题 :Lactate dehydrogenase inhibitors in cosmetic compositions
发明人:BARTOLONE JOHN B; PENKSA CHRISTINE M; SANTHANAM UMA; LANG BRIAN D
权利人:CHESEBROUGH PONDS USA
摘要:Certain combinations of lactate dehydrogenase inhibitors and specific carboxylic acids stimulate keratinocyte proliferation and collagen synthesis in skin.
专利号:US-5853742-A
优先权日:1994-12-20
标题:Cosmetic compositions containing lactate dehydrogenase inhibitors
发明人:BARTOLONE JOHN BRIAN; PENKSA CHRISTINE MARIE; SANTHANAM UMA; LANG BRIAN DAVID
权利人:CHESEBROUGH PONDS USA
摘要:Inhibitors of lactate dehydrogenase stimulate keratinocyte proliferation and collagen synthesis in cutaneous tissues. The inhibitors are used preferably with certain co-active ingredients such as pyruvic acid, acetic acid, acetoacetic acid, beta -hydroxybutyric acid, a Krebs cycle pathway metabolite, an aliphatic saturated or an unsaturated fatty acid containing from 8 to 26 carbon atoms, an omega -hydroxy acid containing from 22 to 34 carbon atoms, glutamic acid, glutamine, valine, alanine, leucine, and mixtures thereof.