CAS: 131833-92-6; (4S,4'S)-2,2'-(Propane-2,2-Diyl)Bis(4-Isopropyl-4,5-Dihydrooxazole)
- 英文名称(4S,4'S)-2,2'-(Propane-2,2-Diyl)Bis(4-Isopropyl-4,5-Dihydrooxazole)
- 中文名称S-4,5-二氢-2-(2-((S)-4,5-二氢-4-异丙基噁唑-2-基)丙-2-基)-4-异丙基噁唑
- IUPAC名称(4S,4'S)-2,2'-(propane-2,2-diyl)bis(4-isopropyl-4,5-dihydrooxazole)
- 其它别名(S,S)-2,2'-Isopropylidenebis(4-Isopropyl-2-Oxazoline); (4S)-4-(Propan-2-yl)-2-{2-[(4S)-4-(Propan-2-yl)-4,5-Dihydro-1,3-Oxazol-2-Yl]Propan-2-Yl}-4,5-Dihydro-1,3-Oxazole; (4S,4'S)-2,2'-(Propane-2,2-Diyl)Bis(4-Isopropyl-4,5-Dihydrooxazole); (4S)-4-Propan-
- CAS编号131833-92-6
- MFCD编号:MFCD08458310
- EINECS号:693-630-6
- 分子式:C15H26N2O2分子量:266.38
- 产品CID: 485096
- 产品分类有机原料 → 杂环化合物
物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
CAS号2026-48-4 L-缬氨醇 | CAS号7321-55-3 二甲基丙二腈 | CAS号5659-93-8 二甲基丙二酰二氯合成工艺路线路线简述
- 合成目标产物 (S)-4,5-Dihydro-2-(2-((S)-4,5-Dihydro-4-Isopropyloxazol-2-yl)Propan-2-yl)-4-Isopropyloxazole 主要起始原料 Dimethylmalonyl Chloride
- (文献来源)合成步骤主要原料 Dimethylmalonyl Chloride
📜L-缬氨醇置于三乙胺,Sodium Hydroxide体系中,用 甲醇,二氯甲烷,水 用作溶剂,化学反应 27.0H,反应生成S-4,5-二氢-2-(2-((S)-4,5-二氢-4-异丙基噁唑-2-基)丙-2-基)-4-异丙基噁唑
参考文献:铜双(恶唑啉)催化苯并吡啶鎓离子的对映选择性炔基化反应.
标题:铜双(恶唑啉)催化苯并吡啶鎓离子的对映选择性炔基化反应.
摘要:通过在双(恶唑啉)铜催化下向炔丙基三氟甲磺酸盐中添加炔烃,可以实现生物相关的苯并二氢呋喃酮和四氢氧杂蒽酮的立体控制结构.通过将各种炔烃添加到2位氢原子的色农酮中,可以实现优异的对映体控制水平(63-98%ee).色农酮与2位酯的炔基烷基化可实现令人满意的对映体控制水平(54-67%ee),产生类似于天然代谢产物中常见的叔醚立体中心.
Doi:10.1002/chem.201904822
海关参考信息
- 2905121000-正丙醇
2905399001-1,3-丙二醇
2909110000-乙醚
2922110001-单乙醇胺 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2022048879-A1
优先权日:2020-08-13
标 题:Synthesis of small molecules inspired by Phomoxanthone A
发明人：ALI RAMEEZ; MATTSON ANITA
权利人:WORCESTER POLYTECH INST
摘要:Methods, compositions, and kits are provided for synthesizing bioactive chromane, the method including: constructing a tertiary ether stereocenter enantioselectively by catalyzed alkynylation of a substituted chromenone to obtain a chromanone; reducing alkyne and ketone in the chromanone to obtain a chroman; and converting ester to methyl group thereby obtaining chromane.
专利号:CN-115304568-A
优先权日:2022-05-17
标 题 :Asymmetric synthesis of 6-azidomethylene-1-aryl-3-oxabicyclo[3,1,0]hexan-2-ones
专利号:WO-2022036040-A1
优先权日:2020-08-13
标 题 :Synthesis of small molecules inspired by phomoxanthone a
专利号:CN-114031573-A
优先权日:2022-01-10
标 题:Method for recovering ligands in asymmetric synthesis of S-(+)-2,2-dimethylcyclopropanecarboxylic acid
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:Roy, M.-N.; Lindsay, V. N. G.; Charette, A. B., Science of Synthesis: Stereoselective Synthesis, (2011) 1, 786.
摘要:Bietti, M.; Dénès, F., Science of Synthesis, (2021) , 539.
摘要:Chemler, S. R.; Kennedy-Ellis, J. J., Science of Synthesis: Special Topics, (2022) 1, 76.
摘要:Chemler, S. R.; Kennedy-Ellis, J. J., Science of Synthesis: Special Topics, (2022) 1, 79.
摘要:Saha, D.; Aggarwal, T.; Sumii, Y.; Yadav, A. K.; Shibata, N., Science of Synthesis: Modern Strategies in Organofluorine Chemistry, (2025) 2.
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