CAS: 79233-15-1; 3-(2-((4As,5R,6R,8Ar)-6-Hydroxy-5-(Hydroxymethyl)-2,5,8A-Trimethyl-3,4,4A,5,6,7,8,8A-Octahydronaphthalen-1-yl)Ethyl)Furan-2(5H)-One
该化合物是一种天然化合物,来自以其药性而著称的Andragistis Paniculata植物,属于被称为二苯胺的化合物类别,具有复杂的双环结构特征,该化合物展示了一系列生物活动,包括抗炎,抗氧化剂和抗微生物特性,使其对药理学研究感兴趣.脱氧和血清分泌物在包括感染和炎症在内的各种条件下的潜在治疗作用进行了研究,其行动机制往往涉及调控与炎症和免疫反应有关的信号路径.该化合物通常从安德洛基斯植物叶和根部提取,其功效和安全特征是正在进行的研究的主题.与许多自然产品一样,其具体特征,如溶性与稳定性,可以因环境条件和提取方法而不同.
- 英文名称3-(2-((4As,5R,6R,8Ar)-6-Hydroxy-5-(Hydroxymethyl)-2,5,8A-Trimethyl-3,4,4A,5,6,7,8,8A-Octahydronaphthalen-1-yl)Ethyl)Furan-2(5H)-One
- 中文名称去氧穿心莲内酯
- IUPAC名称3-(2-((4aS,5R,6R,8aR)-6-hydroxy-5-(hydroxymethyl)-2,5,8a-trimethyl-3,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)ethyl)furan-2(5H)-one
- 其它别名Andrographolide, Deoxy-; Deoxyandrographolide; 4-[2-[(4As,5R,6R,8Ar)-6-Hydroxy-5-(Hydroxymethyl)-2,5,8A-Trimethyl-3,4,4A,6,7,8-Hexahydronaphthalen-1-Yl]Ethyl]-2H-Furan-5-One; 2(5H)-Furanone, 3-[2-[(4As,5R,6R,8Ar)-3,4,4A,5,6,7,8,8A-Octahydro-6-Hydroxy-5-(Hydroxymethyl)-2,5,8A-Trimethyl-1-Naphthalenyl]Ethyl]-; 3-[2-[(4As,5R,6R,8Ar)-3,4,4A,5,6,7,8,8A-Octahydro-6-Hydroxy-5-(Hydroxymethyl)-2,5,8A-Trimethyl-1-Naphthalenyl]Ethyl]-2(5H)-Furanone; 3-(2-((4As,5R,6R,8Ar)-6-Hydroxy-5-(Hydroxymethyl)-2,5,8A-Trimethyl-3,4,4A,5,6,7,8,8A-Octahydronaphthalen-1-yl)Ethyl)Furan-2(5H)-One; Deoxyandrographolide, 10 Mm In Dmso
- CAS编号79233-15-1
- MFCD编号:MFCD03093713
- 分子式:C20H30O4分子量:334.46
- 产品CID: 1786904
物理性质
MSDS等安全信息
- 警示词warning
- 危险描述H303 may be harmful by ingestion +H313 may be harmful by skin contact +h2413 may be harmful by inhalation
- 防范说明P264 wash thoroughly after treatmentp280 wear protective gloves / wear protective clothing / wear protective eye masks / wear protective masksp305 if in eyesp351 rinse carefully with water for a few minutesp338 remove contact lenses (if any) and easy to operate, continue rinsingp337 if eye irritation persistsp2393 get medical advice / care
- 安全声明H303 may be harmful by ingestion +h313 may be harmful by skin contact +h2413 may be harmful by inhalation
上下游产品
CAS号82209-72-1 穿心莲内酯糖苷 | CAS号4176-97-0 14-去氧穿心莲内酯合成工艺路线路线简述
- 42895-61-4 = 79233-15-1
反应条件:1.1 Reagents: Hydrochloric Acid Solvents: Methanol; 1.5 H,Rt
标题:Synthesis Of Andrographolide Analogues And Their Neuroprotection And Neurite Outgrowth-Promoting Activities
作者:Xu,Yuanzhen; Wei,Hongbo; Wang,Jianping; Wang,Weiwei; Gao,Jinming
参考文献:Bioorganic & Medicinal Chemistry 日期:2019 卷标:27(11) 页码:2209-2219
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
2905399001-1,3-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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供应商参考报价(招募中)
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📌 第三方产品分析报告
合成参考文献
参考文献:10.3109/13880209209054010
摘要:Misra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial Activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. International Journal of Pharmacognosy. 1992 Jan;30(4):263–74. doi: 10.3109/13880209209054010.
参考文献:10.1007/978-981-16-8858-4_8
摘要:Pai SR. In Vitro Production of Terpenoids. 2022. In: Nutraceuticals Production from Plant Cell Factory.
参考文献:10.1134/s1021443722602919
摘要:Qu SC, Zeng LJ, Yu SQY, Zhang XY, Zhou YY, Feng XY, Huang JL. Effects of Changeable Ambient UV-B Irradiation on the Accumulation of Diterpene Lactones and Flavonoids in Andrographis paniculata (Burm.f.) Nees. Russ J Plant Physiol. 2023 Jun 22;70(4). doi: 10.1134/s1021443722602919.
参考文献:10.1186/s43066-023-00248-w
摘要:Pandey B, Baral R, Kaundinnyayana A, Panta S. Promising hepatoprotective agents from the natural sources: a study of scientific evidence. Egypt Liver Journal. 2023 Mar 29;13(1). doi: 10.1186/s43066-023-00248-w.
参考文献:10.1007/978-3-031-22075-3_11
摘要:Dev S. Andrographis paniculata. 2023. In: Prime Ayurvedic Plant Drugs.
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