CAS: 62596-29-6; 2-(2,4-Dihydroxyphenyl)-5-Hydroxy-8,8-Dimethyl-3-(3-Methylbut-2-En-1-yl)Pyrano[2,3-F]Chromen-4(8H)-One

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CAS号1216959-03-3 2-[2-(4-methoxy...

📜2-[2-(4-Methoxybenzyloxy)-4-Hydroxyphenyl]-5-Hydroxy-8,8-Dimethyl-3-(3-Methyl-But-2-Enyl)-Pyrano[2,3-F]Chromen-4-One置于吡啶,乙酰氯,乙硫醇,Tin(Ll) Chloride,一水合肼体系中,用 乙腈,四氢呋喃 作为反应溶剂,化学反应 0.33H,以67%的收率获得产物桑辛素
参考文献:The Synthesis Of Morusin As A Potent Antitumor Agent
标题:The Synthesis Of Morusin As A Potent Antitumor Agent
摘要:Morusin. Which Call Be Isolated From Chinese Herbal Medicine. Is Achieved In Which The Longest Linear Sequence Is Only 13 Steps In 12% Overall Yield From Commercially Available Phloroglucinol In Addition,The Metal/etsh Reagents For Regioselective Demethylation Of Polymethylated Morusin Were Described Consequently This Strategy Provided A Concise Route 10 Synthesize The Morusin Analogues As Well Further Biological Studies Of Morusin. It Exhibited Strong Antitumor Effects With Ic(50) Similar To 3 0 Mu M Oil Three Cancel Cells (C) 2009 Elsevier Ltd All Rights Reserved
DOI:10.1016/j.Tet.2009.12.002

专利信息

专利号:US-2007232495-A1
优先权日:2006-03-24
标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
发明人：NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.

专利号:US-10576057-B2
优先权日:2015-05-26
标 题 :Methods for treating muscle wasting and degeneration diseases
发明人：HWANG JAE-KWAN; KIM MI-BO; KIM CHANGHEE; KIM DOUN; CHUNG HEECHUL
权利人:NEWTREE CO LTD
摘要:The present invention relates to a composition for preventing and treating muscle diseases or improving muscular function, containing, as an active ingredient, at least one selected from the group consisting of morusin, kuwanon G, and a Mori Cortex Radicis extract. The Mori Cortex Radicis extract, morusin, or kuwanon G, according to the present invention, has an effect of remarkably enhancing muscular function by increasing the expression of p-mTOR protein involved in muscular protein synthesis, inhibiting the expression of mRNAs of MuRF-1 and atrogin-1 involved in muscular protein degradation, and increasing the expression of mRNAs of MyoD and myogenin involved in muscular differentiation. In addition, the present invention is a natural product so as to be used safely without side effects, thereby being usable in drugs, food, or cosmetics.