CAS: 4232-27-3; 2,4-Dinitrophenyl Acetate

上下游产品

2,4-Dinitrophenol acetic anhydride 1-ethoxy-2-(trimethylsilyl)vinyl acetate potassium 2,4-dinitrophenolate 2,4-Dinitrophenol 1-acetoxy-2-acetylamino-4-nitro-benzene 1-acetoxy-4-acetylamino-2-nitro-benzene 1-piperidin-1-yl-ethanone

📜2,4-二硝基酚,乙酰氯置于吡啶体系中,用 乙醚 作为反应溶剂,化学反应 12.0H,以55%的收率获得产物2,4-二硝基苯酯
参考文献:Investigations On Substituent And Solvent Effects On Solvolysis Reactions Part Ix. The Influence Of Polar Substituents On The Imidazole Catalyzed Hydrolysis Of 2,4-Dinitrophenyl Acetates In Water
标题:Investigations On Substituent And Solvent Effects On Solvolysis Reactions Part Ix. The Influence Of Polar Substituents On The Imidazole Catalyzed Hydrolysis Of 2,4-Dinitrophenyl Acetates In Water
摘要:咪唑催化水解极性取代的2,4-二硝基苯乙酸酯的反应在不同温度下已被研究.观测到的速率与咪唑在羧基碳原子上的双分子亲核加成相一致,随后在水中快速水解n-乙酰咪唑.酯分子酸部分中极性取代基对水解反应的影响可以通过电荷间的偶极-偶极相互作用来描述,正如极性取代乙酸乙酯的中性水解一样.
DOI:10.1039/a901004A

专利信息

专利号:US-5786448-A
优先权日:1996-11-07
标题:Combinatorial libraries of cyclic urea and cyclic thiourea derivatives and compounds therein
发明人：NEFZI ADEL; OSTRESH JOHN M; HOUGHTEN RICHARD
权利人:TREGA BIOSCIENCES INC
摘要:The invention provides a rapid approach for combinatorial synthesis and screening of libraries of cyclic urea and cyclic thiourea compounds. The present invention further provides the compounds made by the combinatorial synthesis.