CAS: 37942-07-7; 3,5-Di-Tert-Butyl-2-Hydroxybenzaldehyde

上下游产品

para-tert-butylphenol 2,4-di-tert-Butylphenol hexamethylenetetramine methanol 3-[1-(3,5-Di-tert-butyl-2-hydroxy-phenyl)-meth-(Z)-ylidene]-dihydro-furan-2-one 2,4-di-tert-butyl-6-({[(1S)-1-(hydroxymethyl)-2-methylpropyl]imino}methyl)phenol (R,R)-N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine 2,4-di-tert-butyl-6-(1-hydroxy-2-methylpropyl)phenol

2,4-二叔丁基苯酚置于铁粉,Iron(II) Chloride 氧气体系中,用 1,4-二氧六环,甲醇 用作溶剂,25.0~70.0 °C,607.95 Kpa 条件下,反应 96.0H,反应生成3,5-二叔丁基水杨醛
参考文献:Ii-Fecl 2 / Fe 0 / O 2体系中的氧化'氨基甲基-2'酚
标题:Ii-Fecl 2 / Fe 0 / O 2体系中的氧化'氨基甲基-2'酚
摘要:在铁和氯化铁(II)的催化量存在下,氧被分子氧氧化的2-氨基甲基苯酚1(a:R = Ch 3 ; B:R = H)主要提供醛2,甲酰胺4和恶嗪5.讨论了这些氧化的机理和反应性的性质.尤其是叔胺氧化物1C在叔胺1A的氧化脱烷基中的可能的中间作用.
Doi:10.1016/s0040-4020(01)81363-6

专利信息

专利号:WO-2017051326-A1
优先权日:2015-09-23
标 题 :New processes and intermediates useful in synthesis of nep inhibitors
发明人：MARTIN BENJAMIN; PENN GERHARD; SCHENKEL BERTHOLD; BOURNE SAMUEL; LAU SHING-HING; LEY Steven
权利人:NOVARTIS AG; MARTIN BENJAMIN; PENN GERHARD; SCHENKEL BERTHOLD; BOURNE SAMUEL; LAU SHING-HING; LEY Steven
摘要:The invention relates to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, in particular neutral endopeptidase (NEP) inhibitors such as sacubitril, and prodrugs thereof.

专利号:US-9951096-B2
优先权日:2008-08-22
标 题 :Catalysts and methods for polymer synthesis
发明人：ALLEN SCOTT D; CHERIAN ANNA E; SIMONEAU CHRIS A; FARMER JAY J; COATES GEOFFREY W; GRIDNEV ALEXEI; LAPOINTE ROBERT E
权利人:SAUDI ARAMCO TECH CO
摘要:The present invention provides unimolecular metal complexes having increased activity in the copolymerization of carbon dioxide and epoxides. Also provided are methods of using such metal complexes in the synthesis of polymers. According to one aspect, the present invention provides metal complexes comprising an activating species with co-catalytic activity tethered to a multidentate ligand that is coordinated to the active metal center of the complex.

专利号:US-11629223-B2
优先权日:2018-01-11
标 题:Synthesis of polymers from cyclic diolides
发明人：CHEN EUGENE Y; TANG XIAOYAN
权利人:UNIV COLORADO STATE RES FOUND
摘要:Biodegradable polymers with advantageous physical and chemical properties are described, as well as methods for making such polymers. In one embodiment, a new chemical synthesis route to technologically important biodegradable poly(3-hydroxybutyrate) (P3HB) with high isotacticity and molecular weight required for a practical use is described. The new route can utilize racemic eight-membered cyclic diolide (rac-DL), meso-DL, or a rac-DL and meso-DL mixture, derived from bio-sourced dimethyl succinate, and enantiomeric (R,R)-DL and (S,S)-DL, optically resolved by metal-based catalysts. With a stereoselective racemic molecular catalyst, the ROP of rac-DL under ambient conditions produces rapidly P3HB with essentially perfect isotacticity ([mm]>99%), high crystallinity and melting temperature (T m =171° C.), as well as high molecular weight and low dispersity (M n =1.54×10 5 g/mol, Ã?=1.01).

专利号:US-9382288-B2
优先权日:2010-10-06
标题 :Derivatives of steroid benzylamines, having an antiparasitic antibacterial, antimycotic and/or antiviral action
发明人：BECKER KATJA; KRIEG REIMAR; SCHÖNECKER BRUNO
权利人:BECKER KATJA; KRIEG REIMAR; SCHÖNECKER BRUNO; UNIV GIESSEN JUSTUS LIEBIG
摘要:The present invention relates to compounds derived from steroids of the general formula (I) n nwherein L represents a linker and R # represents a steroid residue, the use of compounds of the general formula (I) in medicine and for the prophylaxis and/or the treatment of infectious diseases. Furthermore described are pharmaceutical compositions containing at least one compound of the general formula (I). A further aspect of the invention relates to the synthesis of said compounds of the general formula (I).

专利号:US-9242955-B2
优先权日:2007-04-25
标题 :Synthesis of cyclic carbonates
发明人：NORTH MICHAEL
权利人:NORTH MICHAEL; UNIV YORK
摘要:A process for the production of cyclic carbonates comprising contacting an epoxide with carbon dioxide in the presence of a dimeric aluminum(salen) catalyst, and a co-catalyst capable of supplying Y − , where Y is selected from Cl, Br and I, where the dimeric aluminum(salen) catalyst is of formula I:

专利号:WO-2024121335-A1
优先权日:2022-12-07
标题:Synthesis of sulfoximine compounds having a stereogenic sulfur atom
发明人：WILLIAMS SIMON; SMITS HELMARS
权利人:SYNGENTA CROP PROTECTION AG
摘要:A process for the preparation of compound of formula (I) which process comprises: (A) stereoselectively oxidizing a sulfanyl compound of formula (II) followed by (B) stereospecific imination of a sulfinyl compound of formula (III) is disclosed wherein the substituents are as defined in claim 1.