CAS: 29477-54-1; Norepinephrine Impurity 3

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2-(3',4'-dihydroxyphenyl)-3-acetylamino-6-(N-acetyl-2''-aminoethyl)-2,3-dihydro-1,4-benzodioxin 2-chloro-3',4'-dihydroxyacetophenone 3,4-dihydroxyphenylethyleneglycol hydroxytyrosolhydroxytyrosol 3,4-dihydroxyphenylethyleneglycol

📜羟基酪醇置于sodium Tetrahydroborate,Sodium Periodate,高氯酸,维生素 C,酪氨酸酶体系中,用 Aq. Phosphate Buffer 用作溶剂,化学反应 0.56H,反应生成1-(2,3,4-三羟基苯基)乙酮
参考文献:从儿茶酚胺代谢产物衍生的邻喹诺酮类的代谢命运.
标题:从儿茶酚胺代谢产物衍生的邻喹诺酮类的代谢命运.
摘要:邻奎宁酮是通过酶(例如酪氨酸酶)或过渡金属离子氧化邻苯二酚底物而在体内产生的.神经黑素是存在于大脑黑质和大脑蓝斑中的一种深色色素,是通过多巴胺(da)和去甲肾上腺素(ne)与半胱氨酸的相互作用而产生的,但它也掺入了它们的酒精和酸性代谢产物.在这项研究中,我们研究了儿茶酚胺代谢物,3,4-二羟基苯基乙醇(dope),3,4-二羟基苯基乙二醇(dopeg),3,4-二羟基苯基乙酸(dopac)和3,4衍生的邻醌的代谢命运.-二羟基苯基扁桃酸(doma).蘑菇酪氨酸酶氧化邻苯二酚底物,然后进行紫外可见分光光度法.用nabh 3或抗坏血酸还原后进行HPLC分析,可以测量邻醌的半衰期并鉴定其反应产物.分光光度检查表明,最初形成的邻醌在ph 6.8时发生了广泛的降解.HPLC分析表明,Dope-醌和dopeg-醌在ph 6.8下分别以15和30分钟的半衰期降解,在ph 5.3下> 100分钟的半衰期
Doi:10.3390/ijms17020164

专利信息

专利号:CN-115612114-A
优先权日:2021-07-14
标 题:Method and application of copolymer film and its enzymatic self-assembly synthesis

专利号:US-7427690-B2
优先权日:2004-06-05
标 题 :Multifunction “crown complexesâ€? from amino acids and peptides for skin and hair restoration
发明人：GUPTA SHYAM K
权利人:BIODERM RESEARCH
摘要:This invention relates to Schiff's bases derived from amino acids and hydroxyaryl alkyl ketones, or a plant extract containing the same, having general chemical structure in FIG. 1 for topical application. This invention also relates to certain metal complex of said Schiff's bases, which have a crown-like appearance in their three-dimensional chemical structure, as in FIG. 2 . The Schiff's bases and their metal complexes of the present invention are useful for the modulation of metal-activated enzymes and metalloenzymes, such as Phenylalanine Hydroxylase, Tyrosine Transaminase, Phenylalanine Transaminase, Tyrosinase, various MMP (Matrix metalloproteases), Superoxide dismutase, 5-Alpha Reductase, and citrate lyase. These are further suitable for multifunctional topical methods for skin whitening, skin wrinkles reduction, skin antiaging, collagen synthesis, acne control, hair loss prevention, hair graying control, and facial oil control.

专利号:CN-1882602-A
优先权日:2003-10-10
标 题 :Modulation and degradation of hyaluronan synthesis in the treatment of disease