1-Isocyanato-2-(3,3,3-Trifluoroprop-1-En-2-yl)Benzene 以 氘代苯 用作溶剂,化学反应生成4-三氟甲基-2-羟基喹啉 参考文献:Kinetic And Computational Studies Of A Novel Pseudopericyclic Electrocyclization. The First Evidence For Torquoselectivity In A 6-π System 标题:Kinetic And Computational Studies Of A Novel Pseudopericyclic Electrocyclization. The First Evidence For Torquoselectivity In A 6-π System 摘要: Doi:10.1021/ja972701A
专利号:US-7696246-B2 优先权日:1999-08-27 标题:Bicyclic androgen and progesterone receptor modulator compounds and methods 发明人:ZHI LIN; VAN OEVEREN CORNELIS ARJAN; MARTINBOROUGH ESTHER 权利人:LIGAND PHARM INC 摘要:The present invention is directed to compounds, pharmaceutical compositions, and methods for modulating processes mediated by AR and PR. More particularly, the invention relates to nonsteroidal compounds and compositions that are high affinity, high specificity agonists, partial agonists (i.e., partial activators and/or tissue-specific activators) and antagonists for AR and PR. Also provided are methods of making such compounds and pharmaceutical compositions, as well as critical intermediates used in their synthesis.