CAS: 14307-43-8; (2R,3R)-2,3-Dihydroxysuccinic Acid, Ammonia Salt(1:X)

L-(+)-酒石酸二乙酯置于ammonium Hydroxide,盐酸体系中,用 水 用作溶剂,化学反应生成Dl-重酒石酸胆碱
参考文献:一种d-乙酯生产中回收和套用l-(+)-酒石酸的 方法
标题:一种d-乙酯生产中回收和套用l-(+)-酒石酸的 方法
摘要:本发明公开了一种d‑乙酯生产中回收和套用l‑(+)‑酒石酸的方法,包括如下步骤:1),L‑乙酯母液回收l‑(+)‑酒石酸钙晶体;2),D‑乙酯母液回收l‑(+)‑酒石酸双盐水溶液;3),L‑(+)‑酒石酸双盐酸化;4),L‑(+)‑酒石酸单盐酸化回收l‑(+)‑酒石酸;5),减压浓缩,结晶,分离,干燥等处理.本发明采用惰性有机溶剂取代常规水相法回收l‑(+)‑酒石酸,避免了发生副反应的几率,所得产品的纯度和比旋光度均可达到原料质量标准,可直接循环用于d‑乙酯的手性拆分.本发明对d‑乙酯生产过程中的两种组分不同的母液釆取不同的回收处理工艺,显著提高了产品的品质,整个回收条件温和,操作较简单,易于控制.

专利信息

专利号:US-7462470-B2
优先权日:2005-06-17
标 题 :Method for the producing vanillic acid and vanillin from waste residue of rice bran oil by fermentation and biotransformation
发明人：SUN ZHIHAO; ZHENG PU; GUO XINFU; LIN GUANYU; YIN HANGHUA; WANG JUN; BAI YANBING
权利人:ZHEJIANG HANGZHOU XINFU PHARMA
摘要:A method for the production of vanillic acid and vanillin from waste residue (niger) of rice bran oil by microbial fermentation and biotransformation is provided. The method of the present invention comprises the steps of hydrolization of ferulic acid esters in waste residue of rice bran oil to ferulic acid and further conversion into vanillic acid using microbial strain Aspergillus niger CGMCC 0774 screened and preserved by the present inventor, followed by conversion of vanillic acid to produce vanillin using another microbial strain Pycnoporus cinnabarinus CGMCC 1115. The method for the production of vanillin according to the present invention utilizes renewable source from rice processing and alleviates the environmental pollution caused by the chemical synthesis of vanillin.

专利号:CN-111018805-A
优先权日:2019-12-26
标 题 :Synthesis and separation method of pramipexole intermediate