CAS: 10461-98-0; 2-Cyclohexylidene-2-Phenylacetonitrile

📜环己酮,苯乙腈置于potassium Tert-Butylate体系中,化学反应 1.0H,以88%的收率获得2-环亚己基-2-苯基乙腈
参考文献:无磷的空气稳定铱(III)配合物催化仲醇高效催化芳基乙腈的α-烷基化反应
标题:无磷的空气稳定铱(III)配合物催化仲醇高效催化芳基乙腈的α-烷基化反应
摘要:报导了一种定义明确且易于获得的空气稳定的二聚铱(III)络合物,使用仲醇催化芳基乙腈的α-烷基化,并释放出水作为唯一的副产物.α-烷基化反应是在无溶剂条件下于120oc高效进行的,催化剂负载量非常低(0.1-0.01 Mol%).包括环和无环醇在内的各种仲醇以及带有不同官能团的多种芳基乙腈都以高收率转化为相应的α-烷基化产物.机理研究表明,反应通过金属与配体的相互作用,通过活化醇与反应性氢化铱物质的形成而进行的.
Doi:10.1021/acs.Joc.0C02400

专利信息

专利号:US-10647942-B2
优先权日:2016-12-22
标题:Fragrance and flavor materials
发明人：BLANDINO MAUREEN; LANKIN MICHAEL E
权利人:TAKASAGO PERFUMERY CO LTD
摘要:The present disclosure is directed to the synthesis and application of undecavertol derivatives having unique and desired flavor and/or fragrant characteristics. The compounds of the present disclosure can be employed alone or incorporated as fragrance or flavor ingredients in fragrance or flavor compositions. The present disclosure is also directed to consumer products comprising such derivatives and/or fragrance or flavor compositions.

专利号:US-2025091984-A1
优先权日:2022-04-07
标题:Fragrance and flavor materials
发明人：DICKERSON THALIA S; TURESKI ROBERT; BLANDINO MAUREEN
权利人:TAKASAGO PERFUMERY CO LTD
摘要:The present disclosure is directed to the synthesis and application of novel compounds having unique and desired flavor and/or fragrance characteristics. The compounds of the present disclosure can be employed alone or incorporated as fragrance or flavor compounds in fragrance or flavor compositions. The present disclosure is also directed to consumer products comprising such fragrance or flavor compounds and/or fragrance or flavor compositions.

专利号:US-12114681-B2
优先权日:2018-06-04
标题:Fragrance and flavor materials
发明人：BLANDINO MAUREEN; TANUMA KENJI
权利人:TAKASAGO PERFUMERY CO LTD
摘要:The synthesis and application of compounds having unique and desired flavor and/or fragrance characteristics are provided herein. The compounds herein can be employed alone or incorporated as fragrance or flavor ingredients in fragrance or flavor compositions. The application is also directed to consumer products comprising such derivatives and/or fragrance or flavor compositions.

专利号:US-2021198229-A1
优先权日:2018-03-08
标 题 :Fragrance and flavor materials from 1-(2-hydroxy-4-methylcyclohexyl)-ethanone
发明人：DICKERSON THALIA S; LOMBARDO LOUIS J; LANKIN MICHAEL E
权利人:TAKASAGO PERFUMERY CO LTD
摘要:The present disclosure is directed to 1-(2-hydroxy-4-methycyclohexyl)-ethanone derivatives having unique and desired flavor and/or fragrance characteristics, as well as the synthesis and application of the derivatives. The compounds of the present disclosure can be employed alone or incorporated as fragrance or flavor ingredients to modify or enhance already existing fragrance compositions, solvents, media, and the like.

专利号:US-2020062687-A1
优先权日:2016-12-22
标 题:Fragrance and flavor materials
发明人：BLANDINO MAUREEN; LANKIN MICHAEL E
权利人:TAKASAGO PERFUMERY CO LTD
摘要:The present disclosure is directed to the synthesis and application of ethyl linalool derivatives having unique and desired flavor and/or fragrance characteristics. The compounds of the present disclosure can be employed alone or incorporated as fragrance or flavor ingredients in fragrance or flavor compositions. The present disclosure is also directed to consumer products comprising such derivatives and/or fragrance or flavor compositions.

专利号:US-2019350826-A1
优先权日:2016-12-22
标题:Fragrance and flavor materials
发明人：BLANDINO MAUREEN; LANKIN MICHAEL E
权利人:TAKASAGO PERFUMERY CO LTD
摘要:The present disclosure is directed to the synthesis and application of an ethyl linalool derivative having unique and desired flavor and/or fragrant characteristics. Specifically, the compound is represented by Formula (I). The compound of Formula (I) can be employed alone or incorporated as fragrance or flavor ingredients in fragrance or flavor compositions. The present disclosure is also directed to consumer products comprising such derivatives and/or fragrance or flavor compositions.