CAS: 928-45-0; Butyl Nitrate

上下游产品

1-bromo-butane 1-iodo-butane ethene sodium butanolate1-butyl-piperidine butyraldehyde N-butyl-4-methylaniline para-methyl anilinium nitrate

📜正丁醇置于n-Nitro-2,4,6-Trimethylpyridinium Tetrafluoroborate体系中,用 乙腈 作为反应溶剂,化学反应 2.0H,以100%的收率获得产物硝酸丁酯
参考文献:与气候有关的高效异戊二烯硝酸盐和(1R,5S)-(-)-美登醇硝酸盐的有效合成.
标题:与气候有关的高效异戊二烯硝酸盐和(1R,5S)-(-)-美登醇硝酸盐的有效合成.
摘要:在这里,我们报告了几种重要的,与气候相关的硝酸异戊二烯的化学选择性合成,这些合成的硝酸异戊二烯使用硝酸银来介导"卤化物取代硝酸盐".利用易于获得的起始原料,试剂和霍纳-沃兹沃思-埃蒙斯化学方法合成易于分离的,合成通用的"关键构件"(e)-和(z)-3-甲基-4-氯丁-2-En-1-使用便宜的"现货"材料已经获得了醇以及(e)-和(z)-1-(((2-甲基-4-溴丁-2-烯氧基)甲基)-4-甲氧基苯.利用它们的反应性,我们研究了它们进行"硝酸烯丙基卤代烯丙基卤"取代反应的能力,我们证明了反应生成(e)-和(z)-3-甲基-4-羟基丁-2-烯基硝酸酯,以及(e)-和(z)-2-甲基-4-羟基丁-2-烯基硝酸盐('异戊二烯硝酸盐'),总产率为66-80%.使用noesy实验,已经建立了纯化的异戊二烯硝酸盐中的碳-碳双键构型的阐明.进一步举例说明我们的"硝酸盐卤化物"取代化学,我们概述了(1R,2
DOI:10.3762/bjoc.12.103

专利信息

专利号:WO-2006040676-A1
优先权日:2004-10-12
标题 :Nitrosated benzopyran compounds as novel cyclooxygenase-2 selective inhibitors
发明人：TJOENG FOE SIONG; CARTER JEFFERY; SPRINGER JOHN ROBERT; ZUPEC MARK E
权利人:PHARMACIA & UPJOHN CO LLC; TJOENG FOE SIONG; CARTER JEFFERY; SPRINGER JOHN ROBERT; ZUPEC MARK E
摘要:This invention specifically relates to novel cyclooxygenase 2 (COX-2) selective inhibitor compounds that donate, transfer or release nitric oxide, stimulate endogenous synthesis of nitric oxide, elevate endogenous levels of endothelium-derived relaxing factor or is a substrate for nitric oxide synthase. Compounds of particular interest and their analogs defined by formula (I) wherein Z, X, R1, R2, R3, and R4 are as described in the specification. This invention also relates to pharmaceutical compositions and methods for treating COX-2 mediated disorders, such as inflammation and inflammation related disorders.

专利号:US-3862113-A
优先权日:1972-09-22
标 题 :Process for the selective elimination of aralkyloxycarbonyl and trityl n-protecting groups with 2,2,2-trifluoroethanol
发明人：RINIKER BERNHARD; KAMBER BRUNO; SIEBER PETER
权利人:CIBA GEIGY CORP
摘要:A process for the selective elimination of amino protective groups in peptide synthesis, wherein the trityl group and/or an aralkyloxycarbonyl group such as the 2-(p-bi-phenylyl)-2propyloxycarbonyl group is (are) split off in trifluorethanol at a pH of about 4 or 1, respectively.

专利号:RU-1838313-C
优先权日:1987-09-04
标 题:Method of synthesis of spirocompound azolone or its n-oxide derivative or its basic salt with pharmacologically usable cation

专利号:CN-104760939-A
优先权日:2015-03-16
标 题:A kind of synthesis process of sodium azide aqueous phase that n-butanol is recycled

专利号:KR-20000069654-A
优先权日:1996-12-23
标题:Cycloalkyl, Lactam, Lactone and Related Compounds, Pharmaceutical Compositions Comprising Same and Methods for Inhibiting β-Amyloid Peptide Release and/or Its Synthesis by Use of Such Compounds

专利号:CN-104760939-B
优先权日:2015-03-16
标题 :A kind of synthesis process of sodium azide aqueous phase that n-butanol is recycled