CAS: 848902-19-2; 2-Azido-1-(3-Fluorophenyl)Ethan-1-One

该化合物是一种氟芳香酮衍生物,具有一个有zido功能组,使其成为有机合成的多用途中间体,3-氟联苯团的存在提高了其在电子和核生殖替代反应中的回活动性,而Azido组允许点击化学应用,如Cu(I)-催化的azide-alkyne循环(CuAAC),该化合物在建立复杂的分子结构的制药和材料科学研究中特别有用,其结构特征使得能够进行选择性的修改,有利于氟化生物活性化合物或高级聚合物的开发,在受控制条件下的高纯度和稳定性确保了合成工作流程的可靠性能.

英文名称2-Azido-1-(3-Fluorophenyl)Ethan-1-One
中文名称2-叠氮基-1-(3-氟苯基)乙烷-1-酮
IUPAC名称2-azido-1-(3-fluorophenyl)ethan-1-one
其它别名2-Azido-1-(3-Fluoro-Phenyl)-Ethanone; 2-Azido-1-(3-Fluorophenyl)Ethan-1-One
CAS编号848902-19-2
MFCD编号:MFCD03790999
分子式:C8H6FN3O分子量:179.15
产品CID: 1839992

相似结构搜索
InChIKey: FINVHPDIWMTLSD-UHFFFAOYSA-N
InChI=1S/C8H6FN3O/c9-7-3-1-2-6(4-7)8(13)5-11-12-10/h1-4H,5H2
计算化学: 氢键受体数3.0氢键供体数*可旋转键数3.0

MSDS等安全信息

上下游产品

2-bromo-1-(3-fluorophenyl)ethanone 1-(3-fluorophenyl)ethanone 3-fluorostyrene

合成工艺路线路线简述

455-36-7 = 848902-19-2
反应条件:1.1 Reagents: P-Toluenesulfonic Acid,N-Bromosuccinimide Solvents: Acetonitrile; 0 °C; 1 H,Reflux; Reflux -> Rt1.2 Reagents: Sodium Azide; 4 H,Rt
标题:New Carbazole Linked 1,2,3-Triazoles As Highly Potent Non-Sugar α-Glucosidase Inhibitors
作者:Iqbal,Shazia; Khan,Maria Aqeel; Javaid,Kulsoom; Sadiq,Rabia; Fazal-Ur-Rehman,Saba; Et Al
参考文献:Bioorganic Chemistry 日期:2017 卷标:74 页码:72-81]

455-36-7 = 848902-19-2
反应条件:1.1 Reagents: P-Toluenesulfonic Acid,N-Bromosuccinimide Solvents: Acetonitrile1.2 Reagents: Sodium Azide
标题:Indole-Linked 1,2,3-Triazole Derivatives Efficiently Modulate Cox-2 Protein And Pge2 Levels In Human Thp-1 Monocytes By Suppressing Age-Ros-Nf-Kβ Nexus
作者:Jahan,Humera; Siddiqui,Nimra Naz; Iqbal,Shazia; Basha,Fatima Z.; Khan,Maria Aqeel; Et Al
参考文献:Life Sciences 日期:2022 卷标:291]

350-51-6 = 848902-19-2
反应条件:1.1 Reagents: Azidotrimethylsilane,Oxygen Catalysts: Diphenyl Diselenide,Rose Bengal Solvents: Acetonitrile; 2 H,Rt
标题:Visible-Light-Enabled Oxyazidation Of Alkenes Leading To α-Azidoketones In Air
作者:Wei,Wei; Cui,Huanhuan; Yue,Huilan; Yang,Daoshan
参考文献:Green Chemistry 日期:2018 卷标:20(14) 页码:3197-3202]

350-51-6 = 848902-19-2
反应条件:1.1 Reagents: Tetrabutylammonium Tetrafluoroborate,Azidotrimethylsilane,Oxygen Solvents: Methanol; 3 H,10 °C
标题:Electrochemical Difunctionalization Of Styrenes Via Chemoselective Oxo-Azidation Or Oxo-Hydroxyphthalimidation
作者:Ye,Zenghui; Zhu,Rongjin; Wang,Feng; Jiang,Haobin; Zhang,Fengzhi
参考文献:Organic Letters 日期:2021 卷标:23(21) 页码:8240-8245]

53631-18-8 = 848902-19-2
反应条件:1.1 Reagents: Sodium Azide Solvents: Dimethyl Sulfoxide; 20 Min,Rt
标题:Regiodivergent And Stereoselective Hydroxyazidation Of Alkenes By Biocatalytic Cascades
作者:Wu,Jing-Fei; Wan,Nan-Wei; Li,Ying-Na; Wang,Qing-Ping; Cui,Bao-Dong; Et Al
参考文献:Iscience 日期:2021 卷标:24(8)