CAS: 79-63-0; (3S,5R,10S,13R,14R,17R)-4,4,10,13,14-Pentamethyl-17-((R)-6-Methylhept-5-En-2-yl)-2,3,4,5,6,7,10,11,12,13,14,15,16,17-Tetradecahydro-1H-Cyclopenta[a]Phenanthren-3-Ol

上下游产品

CAS号2671-68-3 lanosteryl acetate | CAS号14050-42-1 2,3-Oxidosqualene | CAS号469-38-5 环阿尔廷醇 | CAS号124770-75-8 [(3S,5R,10S,13R... | CAS号63976-67-0 24(R,S)-3β-acet... | CAS号13553-26-9 24-Ketolanoster... | CAS号68612-49-7 3β-acetoxy-(24E... | CAS号1255-26-1 Lanost-8-en-3-one | CAS号111420-56-5 32-hydroxylanosterol | CAS号64284-64-6 FF-MAS

24,25-Dihydrolanosteryl Acetate置于氢氧化钾,乙酸酐体系中,用 乙醇,二氯甲烷 作为反应溶剂,化学反应 8.0H,反应生成 羊毛甾醇
参考文献:A Low-Toxicity Method For The Separation Of Lanosterol And Dihydrolanosterol From Commercial Mixtures
标题:A Low-Toxicity Method For The Separation Of Lanosterol And Dihydrolanosterol From Commercial Mixtures
摘要:We Describe An Inexpensive,Low-Toxicity And High-Yielding Method For The Production Of Pure Lanosterol And Dihydrolanosterol From The Commercially Available Mixture. Optimum Conditions Are Presented For The One-Pot Production Of The Intermediate 24,25 Vicinal Diol Of Lanosterol Acetate (Via Either Epoxidation Or Hydroxyhalogenation) Which Is Readily Separated From The Unreacted Dihydrolanosterol Acetate. The Lanosterol Diol Can Then Be Converted To Pure (>97%) Lanosterol. Hypophosphorous Acid Was Used For Both The Conversion Of The Epoxide To The Diol,And As A Catalyst For The Hydroxyhalogenation By N-Halosuccinimides Of The Olefinic Bond. (C) 2004 Elsevier Inc. All Rights Reserved.
DOI:10.1016/j.Steroids.2004.07.003

专利信息

专利号:US-9943544-B2
优先权日:2015-03-18
标 题:Process for bio synthesis of nano arsenic trioxide and its use in treatment of diseases including cancer
发明人：BENDALE YOGESH NARAYAN; BENDALE VINEETA YOGESH
权利人:BENDALE YOGESH NARAYAN; BENDALE VINEETA YOGESH
摘要:The present invention is a process for bio synthesis of nano arsenic trioxide defined by its low toxicity, higher bio availability and nano particle size with the aid of buttermilk, goat urine, dolichos biflorous and other plant materials such as ginger, momordica charantia and musa paradisiaca . The invention is carried out in different steps involving purification of crude form of arsenic trioxide by boiling it with buttermilk, goat urine and extract of dolichos biflorous in subsequent steps, followed by the trituration of the bio purified arsenic trioxide with extracts of ginger and momordica charantia in subsequent steps and heating of the dry product obtained after trituration with musa paradisiaca resulting in the production of novel nano arsenic trioxide. The product is effective in the treatment of various diseases including different types of cancer in animals and humans. The product obtained through the process is less toxic with higher bio availability.

专利号:WO-2021019558-A1
优先权日:2019-07-30
标题 :An efficient method for synthesis of 5-(3-pyridyl)-2,2'-bithiophene(sensitizer)
发明人：DATLA ANUPAMA; NAGRE PRASHANT; TAMORE JAGDISH; PRABHU MANOJKUMAR SADANAND; KADAM SACHIN VASANT
权利人:FERMENTA BIOTECH LTD
摘要:The present invention discloses an efficient process for synthesis of photosensitizer, 5-(3-pyridyl)-2,2'-bithiophene in high yield and purity.

专利号:WO-2021019559-A1
优先权日:2019-07-30
标题 :Synthesis of 5-(3-pyridyl)-2,2'-bithiophene(sensitizer)
发明人：DATLA ANUPAMA; NAGRE PRASHANT; TAMORE JAGDISH; PRABHU MANOJKUMAR SADANAND; KADAM SACHIN VASANT
权利人:FERMENTA BIOTECH LTD
摘要:Disclosed herein is a novel simple, short process for synthesis of the photosensitizer, 5-(3-pyridyl)-2,2'-bithiophene.

专利号:WO-2025109557-A1
优先权日:2023-11-24
标题:Process for the synthesis of monoesters of ethylenediaminetetraacetic acid
发明人：TERAZONO YUICHI
权利人:NUTRIEN AG SOLUTIONS CANADA INC
摘要:A process for the synthesis of a compound of Formula (I) is provided. (I) wherein R is selected from the group consisting of alkyl, alkenyl, alkynyl, and steroidyl. The process comprises reacting a compound of Formula (IIa), Formula (IIb) or a mixture thereof with a compound of Formula R-X, to obtain a compound of Formula (IIIa), a compound of Formula (IIIb) or a mixture thereof, wherein A+ is a cesium cation, a quaternary ammonium cation or a quaternary phosphonium cation, and X is a leaving group; and reacting the compound of Formula (IIIa), compound of Formula (IIIb) or mixture thereof with an acid to obtain a reaction product which comprises the compound of Formula (I). (IIa) (IIb) (IIIa) (IIIb)

专利号:US-12358871-B2
优先权日:2019-05-15
标 题:Photochemical synthesis of vitamin D3 using sensitizers
发明人：DATLA ANUPAMA; NAGRE PRASHANT; TAMORE JAGDISH; TRIVIKRAM SREENATH; DEGAONKAR GAJANAN
权利人:FERMENTA BIOTECH LTD
摘要:The present invention discloses an improved photochemical synthesis of vitamin D3 from 7-dehydrocholesterol alone or in combination with sterol precursors in presence of the photosensitizer of Formula I in high yield and with reduced levels of impurities.

专利号:US-12220411-B1
优先权日:2023-07-25
标题 :Application of PTGDS inhibitor in preparation of drug for treating cataracts
发明人：LI JIN; LIU JIASHENG; XU YITONG; ZHU MENGCHAO; SUN HAISEN
权利人:THE EYE HOSPITAL OR WENZHOU MEDICAL UNIV; THE EYE HOSPITAL OF WENZHOU MEDICAL UNIV
摘要:Application of a PTGDS inhibitor in preparation of a drug for treating cataracts is provided. As an effective and selective PTGDS inhibitor, AT-56 competitively inhibits production of PGD2 by occupying a catalytic site of PTGDS. The PTGDS catalyzes synthesis of the PGD2 to cause an oxidative stress injury of human lens epithelial cells, thereby promoting occurrence and development of aging and opacity of a lens. By reducing apoptosis caused by the oxidative stress injury, a degree of the cataracts can be effectively reduced.