CAS: 7783-13-3; Sodium Ammonium Hydrogen Phosphate Tetrahydrate

该化合物是一种无机化合物,既用作铵离子又用作磷酸盐的来源,一般是白色晶状固体,在水中高度溶解,在化肥和食品添加剂等各种应用中有用;四氢酸钠形式表明,它每个配方单元含有4个水分子,有助于其稳定性和溶解性;这种化合物经常用于生物化学应用,特别是缓冲溶液,因为它能够保持pH水平;此外,它可以作为微生物媒介的一种营养来源;虽然一般认为在粮食和农业中使用是安全的,但必须谨慎处理,因为过度接触可能会引起健康问题;总的来说,磷酸钠四氢酸盐因其在工业和实验室环境中的多功能特性而具有价值.

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13011-54-6 7722-76-1 10101-89-0

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    专利信息


    专利号:US-4886910-A
    优先权日:1987-02-17
    标题 :Cyanoguanidine derivative and process for preparation thereof
    发明人:TAN HIROAKI; KATO KOJI; IMUTA JUNICHI; KIHARA NORIAKI
    权利人:MITSUI PETROCHEMICAL IND
    摘要:The present invention provides a cyanoguanidine derivtive which is a precursor for the synthesis of N-cyano-N'-methyl-N'-[2-{(5-methyl-1H-imidazol-4-yl)methylothio}ethyl]-guanidine (Cimetidine) or its relted compound, which has an action of controlling secretion of acid in the stomach based on the histamine H 2 receptor antagonism and is valuable as a drug for treating gastric ulcer. This cyanoguanidine derivative is prepared by reacting a haloketone derivative with an ammonium salt and a lower fatty acid salt or by reacting other cyanoguanidine derivative with an ammonium salt.

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    主要参考文献

    [参考文献]: Keiko Inami, Et Al. Transnitrosation Of Non-Mutagenic N-Nitrosoproline Forms Mutagenic N-Nitroso-N-Methylurea. Bioorg Med Chem. 2015 Jul 1;23(13):3297-302.
    [参考文献]: Toine F H Bovee, Et Al. Are Effects Of Common Ragwort In The Ames Test Caused By Pyrrolizidine Alkaloids. Mutat Res. 2015 Aug:778:1-10.

    合成参考文献


    参考文献:10.1186/s41021-019-0137-4
    摘要:Inami K, Asada Y, Harada T, Okayama Y, Usui N, Mochizuki M. Antimutagenic components in Spatholobus suberectus Dunn against N-methyl-N-nitrosourea. Genes and Environment. 2019 Dec 11;41(1):22. doi: 10.1186/s41021-019-0137-4.
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