CAS: 77772-72-6; 2-Fluoro-3-Methylphenol

该化合物是一种属于酚类的有机化合物,其特点是附于苯环的氢氧基(-OH)组,该化合物具有氟原子和一个甲基组,分别是芳香环上的替代物,具体地说在2和3个位置上;它一般没有颜色,可粉黄黄色液体或固体,视其纯度和形态而定;氟原子的存在会增强它的再活动性,并能影响其物理特性,例如沸点和熔点,以及各种溶剂中的溶性. 2-Fluoro-3-甲基酚对各种化学应用都有意义,包括作为制药和农用化学合成的中间体.此外,它可能表现出抗微生物特性,使其与易受感染性物质防腐蚀剂的发展有关.许多化学物质,由于潜在的毒性或环境影响,应当按照适当的安全准则谨慎处理.

英文名称2-Fluoro-3-Methylphenol
中文名称2-氟-3-甲基苯酚
IUPAC名称2-fluoro-3-methylphenol
其它别名Phenol, 2-Fluoro-3-Methyl-; Qtcqbpowswcjlq-Uhfffaoysa-N; 2-Fluoro-3-Methylphenol; 2-Fluoro-3-Methyl-Phenol; 2-Fluoro-3-Methylphenol, Aldrichcpr
CAS编号77772-72-6
MFCD编号:MFCD09835186
EINECS号:963-356-4
分子式:C7H7FO
分子量:126.13
产品CID: 1772026
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
产品信息参考
InChIKey: QTCQBPOWSWCJLQ-UHFFFAOYSA-N
InChI=1S/C7H7FO/c1-5-3-2-4-6(9)7(5)8/h2-4,9H,1H3…
计算化学: 氢键受体数1.0氢键供体数1.0可旋转键数0.0

MSDS等安全信息

GHS象形图
GHS符号GHS07;
注释: Exclamation mark
危险类别急性毒性类别4(经口)
急性毒性类别4(吸入)
急性毒性类别4(经皮)
特定目标器官毒性 - 单次接触类别3
皮肤腐蚀/刺激类别2
严重眼损伤类别1
警示词Warning(警告)
危险描述H302 |吞咽有害.
H332 |吸入有害.
H312 |皮肤接触有害.
H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H318 |造成严重眼损伤.
防范说明P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P501
危险等级3
UN编号1993.0
危险品标志F+
包装等级Ⅲ
安全声明H303+H313+H333

欧盟法规

C&L通报

上下游产品

3-methyl-phenol 2-tert-Butyl-5-methylphenol 2-fluoro-4,4-dimethoxy-3-methylcyclohexa-2,5-dienone 6-chloro-2-fluoro-4-methoxy-3-methylphenol

合成工艺路线路线简述

6-叔丁基间甲酚置于三氯化铝,乙酰基次氟酸酯体系中,用一氟三氯甲烷,甲苯作为反应溶剂,化学反应 5.0H,反应生成 2-氟-3-甲基苯酚
参考文献:Takemoto,Ichiki; Yamasaki,Kaori,Bioscience,Biotechnology And Biochemistry,1994,Vol. 58,# 3,P. 594-595
标题:Takemoto,Ichiki; Yamasaki,Kaori,Bioscience,Biotechnology And Biochemistry,1994,Vol. 58,# 3,P. 594-595

海关参考信息

2902300000-甲苯
2908199090-其他酚的卤化衍生物
2908999090-其他酚的硝化衍生物
2918290000-其他含酚基羧酸
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-11512062-B2
优先权日:2018-10-15
标题:Process for the synthesis of piperazinyl-ethoxy-bromophenyl derivates and their application in the production of compounds containing them
发明人：BEAUREGARD LOUIS-PHILIPPE; BERTRAND MARTIAL; GIGUERE PASCALL; HARDOUIN CHRISTOPHE; SCHIAVI BRUNO
权利人:SERVIER LAB
摘要:Process for the industrial synthesis of the compound of formula (I):

专利号:WO-2020078875-A1
优先权日:2018-10-15
标题:New process for the synthesis of piperazinyl-ethoxy-bromophenyl derivates and their application in the production of compounds containing them

专利号:EP-3867233-A1
优先权日:2018-10-15
标题:New process for the synthesis of piperazinyl-ethoxy-bromophenyl derivates and their application in the production of compounds containing them

专利号:TW-I856981-B
优先权日:2018-10-15
标题:New process for the synthesis of piperazinyl-ethoxy-bromophenyl derivatives and their application in the production of compounds containing them

专利号:US-2021380549-A1
优先权日:2018-10-15
标题 :New process for the synthesis of piperazinyl-ethoxy-bromophenyl derivates and their application in the production of compounds containing them

专利号:CA-3115608-A1
优先权日:2018-10-15
标题 :Process for the synthesis of piperazinyl-ethoxy-bromophenyl derivatives