CAS: 77029-83-5; 11-Acetyl-3,8,12-Trihydroxy-1,5,6,10-Tetramethoxy-12-Methyl-12,13-Dihydro-2H-Cyclohepta[ghi]Perylene-2,9(11H)-Dione

该化合物具有强大的抗氧化剂和抗炎特性.它独特的结构赋予高度稳定性和生物利用率,使它成为各种炎症的治疗应用的有希望的候选体.Hypocrellin的选择性行动和最小副作用将它定位为有价值的研究工具和潜在治疗剂.

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合成工艺路线路线简述

    海关参考信息

    专利信息


    专利号:US-7157477-B2
    优先权日:2000-10-25
    标题 :Aliphatic amino-substituted demethoxylated hypocrellins and their synthesis
    发明人:ZHANG MANHUA; XU SHANGJIE; WU TAO; CHEN SHEN; SHEN TAO
    权利人:INST OF PHOTOGRAPHIC CHEMISTRY
    摘要:The invention involves a methods and compositions for use in photodynamic therapy. Novel perylenequinone derivatives, conjugates comprising perylenequinone derivatives and a binding agent, and methods of treatment using these compositions are disclosed. The present invention relates to the field of photosensitizers possessing photodynamic activities. They possess high photodynamic activities and low dark toxicities, which makes them as more potent photodynamic agents than HPD against cancer and AIDS virus.

    专利号:US-2008050747-A1
    优先权日:2006-03-30
    标题:Articles having localized molecules disposed thereon and methods of producing and using same
    发明人:KORLACH JONAS; TURNER STEPHEN
    权利人:PACIFIC BIOSCIENCES CALIFORNIA
    摘要:Sequencing methods and compositions, substrates, devices and systems are provided. Methods include synthesizing a nascent nucleic acid sequence that is greater than 100 bases in length and sequencing the nucleic acids by detecting synthesis. Compositions and substrates that include polymerization complexes for the methods are included.

    专利号:CN-1295341-C
    优先权日:2005-01-17
    标 题 :Biologic synthesis of perylene quinone compound

    专利号:CN-1680562-A
    优先权日:2005-01-17
    标 题 :Biologic synthesis of perylene quinone compound

    专利号:KR-20050099397-A
    优先权日:2004-04-10
    标 题:Method of labeling translated protein in cell-free protein synthesis using the complex composed of non-radioactive fluorescent dye and aminoacylated trna

    专利号:CN-115216480-A
    优先权日:2022-04-08
    标题 :A kind of oleocanthin synthesis gene Omef and its utilization

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1021/acs.jnatprod.0c00492
    摘要:Al Subeh ZY, Raja HA, Monro S, Flores-Bocanegra L, El-Elimat T, Pearce CJ, McFarland SA, Oberlies NH. Enhanced Production and Anticancer Properties of Photoactivated Perylenequinones. J. Nat. Prod. 2020 Aug 10;83(8):2490–500. doi: 10.1021/acs.jnatprod.0c00492.
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